lipopolysaccharide-mediated signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system. (Gene Ontology, GO_0031663)
External Link http://amigo.geneontology.org/amigo/term/GO:0031663
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Genes

28 genes participating in the lipopolysaccharide-mediated signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
HCK HCK proto-oncogene, Src family tyrosine kinase
IL18 interleukin 18
IL1B interleukin 1, beta
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRF3 interferon regulatory factor 3
LBP lipopolysaccharide binding protein
LY96 lymphocyte antigen 96
LYN LYN proto-oncogene, Src family tyrosine kinase
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MTDH metadherin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS3 nitric oxide synthase 3 (endothelial cell)
PRKCE protein kinase C, epsilon
PTAFR platelet-activating factor receptor
RIPK2 receptor-interacting serine-threonine kinase 2
SCARB1 scavenger receptor class B, member 1
STAT1 signal transducer and activator of transcription 1, 91kDa
TGFB1 transforming growth factor, beta 1
TICAM1 toll-like receptor adaptor molecule 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor