lipid particle Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. (Gene Ontology, GO_0005811)
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Genes

336 proteins co-occuring with the lipid particle cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PLIN1 perilipin 1 2.98407
PLIN2 perilipin 2 2.86508
PLIN3 perilipin 3 2.27208
PLIN5 perilipin 5 2.08963
PNPLA2 patatin-like phospholipase domain containing 2 2.0012
LIPE lipase, hormone-sensitive 1.98337
CIDEC cell death-inducing DFFA-like effector c 1.84429
PPARG peroxisome proliferator-activated receptor gamma 1.74067
PLIN4 perilipin 4 1.6678
LPL lipoprotein lipase 1.52315
INS insulin 1.47004
DGAT1 diacylglycerol O-acyltransferase 1 1.45138
ABHD5 abhydrolase domain containing 5 1.44516
DGAT2 diacylglycerol O-acyltransferase 2 1.40298
FASN fatty acid synthase 1.3896
FABP4 fatty acid binding protein 4, adipocyte 1.31142
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.2905
SREBF1 sterol regulatory element binding transcription factor 1 1.25232
APOB apolipoprotein B 1.22932
POMC proopiomelanocortin 1.21066
APOE apolipoprotein E 1.20705
RAB18 RAB18, member RAS oncogene family 1.14392
CIDEB cell death-inducing DFFA-like effector b 1.13216
FITM2 fat storage-inducing transmembrane protein 2 1.10715
LEP leptin 1.10256
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1.08425
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.02629
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.01784
FITM1 fat storage-inducing transmembrane protein 1 0.969848
CAV1 caveolin 1, caveolae protein, 22kDa 0.966956
CES1 carboxylesterase 1 0.966474
PNLIP pancreatic lipase 0.963107
MTTP microsomal triglyceride transfer protein 0.960707
ALB albumin 0.952096
AUP1 ancient ubiquitous protein 1 0.927483
ALPPL2 alkaline phosphatase, placental-like 2 0.923259
ALPL alkaline phosphatase, liver/bone/kidney 0.922322
APOA5 apolipoprotein A-V 0.921854
ALPP alkaline phosphatase, placental 0.921854
ACPP acid phosphatase, prostate 0.909716
PPARA peroxisome proliferator-activated receptor alpha 0.899962
SPG20 spastic paraplegia 20 (Troyer syndrome) 0.898109
LIPA lipase A, lysosomal acid, cholesterol esterase 0.897183
LPIN2 lipin 2 0.889321
PNPLA3 patatin-like phospholipase domain containing 3 0.870426
G0S2 G0/G1 switch 2 0.841941
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 0.834138
SCARB1 scavenger receptor class B, member 1 0.833679
CD36 CD36 molecule (thrombospondin receptor) 0.827712
LPIN1 lipin 1 0.825418
NCEH1 neutral cholesterol ester hydrolase 1 0.809817
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.789649
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.787359
SOAT1 sterol O-acyltransferase 1 0.778669
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.768171
LDLR low density lipoprotein receptor 0.765893
SCARB2 scavenger receptor class B, member 2 0.747737
ELOVL3 ELOVL fatty acid elongase 3 0.746833
APOA1 apolipoprotein A-I 0.732422
LPA lipoprotein, Lp(a) 0.729284
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.726152
METTL7A methyltransferase like 7A 0.715902
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 0.713238
FAF2 Fas associated factor family member 2 0.707924
ACACA acetyl-CoA carboxylase alpha 0.69427
METRNL meteorin, glial cell differentiation regulator-like 0.692516
ASCL3 achaete-scute family bHLH transcription factor 3 0.692516
PRDM16 PR domain containing 16 0.686827
ACSL3 acyl-CoA synthetase long-chain family member 3 0.683335
CAT catalase 0.662935
CAV2 caveolin 2 0.657326
GIMAP2 GTPase, IMAP family member 2 0.656895
LTF lactotransferrin 0.656033
CFD complement factor D (adipsin) 0.643144
BTN1A1 butyrophilin, subfamily 1, member A1 0.643144
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6 0.636295
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 0.63544
CEL carboxyl ester lipase 0.63544
ATG2B autophagy related 2B 0.635013
RETN resistin 0.631598
CSN1S1 casein alpha s1 0.631171
APOC2 apolipoprotein C-II 0.622229
BGLAP bone gamma-carboxyglutamate (gla) protein 0.612471
CES3 carboxylesterase 3 0.612471
FAAH2 fatty acid amide hydrolase 2 0.611625
ACOT2 acyl-CoA thioesterase 2 0.605284
PNPLA1 patatin-like phospholipase domain containing 1 0.601909
CLEC3B C-type lectin domain family 3, member B 0.596435
APOC3 apolipoprotein C-III 0.588037
KRAS Kirsten rat sarcoma viral oncogene homolog 0.585105
CLPS colipase, pancreatic 0.576329
SQLE squalene epoxidase 0.569248
CSN2 casein beta 0.568832
RUNX2 runt-related transcription factor 2 0.565508
CARS cysteinyl-tRNA synthetase 0.563847
APOA4 apolipoprotein A-IV 0.559285
AQP7 aquaporin 7 0.555145
ACSL1 acyl-CoA synthetase long-chain family member 1 0.547297
LYPD2 LY6/PLAUR domain containing 2 0.538238
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.536183
OSBPL2 oxysterol binding protein-like 2 0.530438
SREBF2 sterol regulatory element binding transcription factor 2 0.528798
CD34 CD34 molecule 0.52675
LMLN leishmanolysin-like (metallopeptidase M8 family) 0.523476
THY1 Thy-1 cell surface antigen 0.522659
METRN meteorin, glial cell differentiation regulator 0.519389
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.512862
CD44 CD44 molecule (Indian blood group) 0.51164
PLA2G1B phospholipase A2, group IB (pancreas) 0.499447
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.496205
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.496205
PNLIPRP1 pancreatic lipase-related protein 1 0.488923
ARFRP1 ADP-ribosylation factor related protein 1 0.475223
ACADVL acyl-CoA dehydrogenase, very long chain 0.472412
SOD2 superoxide dismutase 2, mitochondrial 0.466399
CCR3 chemokine (C-C motif) receptor 3 0.466399
ALOX5 arachidonate 5-lipoxygenase 0.461998
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.461998
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.461998
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.459203
FABP12 fatty acid binding protein 12 0.454816
FABP3 fatty acid binding protein 3, muscle and heart 0.454418
VAMP4 vesicle-associated membrane protein 4 0.453621
AWAT1 acyl-CoA wax alcohol acyltransferase 1 0.447656
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 0.445275
CIDEA cell death-inducing DFFA-like effector a 0.444085
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.441708
SCP2 sterol carrier protein 2 0.44052
AADAC arylacetamide deacetylase 0.438937
LPIN3 lipin 3 0.437356
HM13 histocompatibility (minor) 13 0.43617
RAB40C RAB40C, member RAS oncogene family 0.43538
STAR steroidogenic acute regulatory protein 0.433407
UBAC2 UBA domain containing 2 0.427497
CTSC cathepsin C 0.422389
FANK1 fibronectin type III and ankyrin repeat domains 1 0.417294
CXCL6 chemokine (C-X-C motif) ligand 6 0.414555
PNPLA5 patatin-like phospholipase domain containing 5 0.414164
CRTC2 CREB regulated transcription coactivator 2 0.412992
BTN3A1 butyrophilin, subfamily 3, member A1 0.412601
DLK1 delta-like 1 homolog (Drosophila) 0.410649
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.405971
SNAP23 synaptosomal-associated protein, 23kDa 0.405193
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.402081
CPT2 carnitine palmitoyltransferase 2 0.401693
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 0.400527
OSM oncostatin M 0.398975
ARF1 ADP-ribosylation factor 1 0.39471
FOXO1 forkhead box O1 0.393162
CD68 CD68 molecule 0.390455
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.389296
APOA2 apolipoprotein A-II 0.387751
BORA bora, aurora kinase A activator 0.387365
MCAM melanoma cell adhesion molecule 0.383895
RBP1 retinol binding protein 1, cellular 0.381199
BTN2A1 butyrophilin, subfamily 2, member A1 0.380045
TRIM38 tripartite motif containing 38 0.37697
TLR2 toll-like receptor 2 0.372749
TRIM56 tripartite motif containing 56 0.363567
VCAM1 vascular cell adhesion molecule 1 0.363567
ADD1 adducin 1 (alpha) 0.363567
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 0.362804
PLA2G12B phospholipase A2, group XIIB 0.358609
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.355944
ACAT1 acetyl-CoA acetyltransferase 1 0.351762
INSIG1 insulin induced gene 1 0.351382
REEP1 receptor accessory protein 1 0.348346
LOX lysyl oxidase 0.347587
STARD4 StAR-related lipid transfer (START) domain containing 4 0.346071
ATG2A autophagy related 2A 0.344178
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.340017
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.336241
LYZ lysozyme 0.33511
CCL2 chemokine (C-C motif) ligand 2 0.334356
STX5 syntaxin 5 0.330966
ACOX1 acyl-CoA oxidase 1, palmitoyl 0.328332
LALBA lactalbumin, alpha- 0.326078
AEBP1 AE binding protein 1 0.32195
IRF6 interferon regulatory factor 6 0.321575
TF transferrin 0.318205
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.316334
CCNF cyclin F 0.315586
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.313344
TP63 tumor protein p63 0.312597
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.308867
FAR2 fatty acyl CoA reductase 2 0.308494
SH3GLB2 SH3-domain GRB2-like endophilin B2 0.308494
CAV3 caveolin 3 0.308122
GPR84 G protein-coupled receptor 84 0.308122
GIMAP7 GTPase, IMAP family member 7 0.305143
RBP5 retinol binding protein 5, cellular 0.304771
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.30254
LGALS12 lectin, galactoside-binding, soluble, 12 0.300682
PRL prolactin 0.29994
ESR1 estrogen receptor 1 0.299197
IRS1 insulin receptor substrate 1 0.298826
SNCAIP synuclein, alpha interacting protein 0.298826
MC5R melanocortin 5 receptor 0.297713
TPD52L2 tumor protein D52-like 2 0.296601
ALPI alkaline phosphatase, intestinal 0.294007
IGF1 insulin-like growth factor 1 (somatomedin C) 0.293267
OSBP oxysterol binding protein 0.290678
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.285876
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.283663
NSL1 NSL1, MIS12 kinetochore complex component 0.283295
LTB4R leukotriene B4 receptor 0.282926
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.281821
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.281085
PPP1R3B protein phosphatase 1, regulatory subunit 3B 0.275202
PATL1 protein associated with topoisomerase II homolog 1 (yeast) 0.273734
LTC4S leukotriene C4 synthase 0.273
TLR4 toll-like receptor 4 0.270068
LARP1 La ribonucleoprotein domain family, member 1 0.269701
ACACB acetyl-CoA carboxylase beta 0.269701
ARL1 ADP-ribosylation factor-like 1 0.269701
MIR26B microRNA 26b 0.263485
ATG7 autophagy related 7 0.26166
RBP4 retinol binding protein 4, plasma 0.260202
LYPLA1 lysophospholipase I 0.258016
PLA2G16 phospholipase A2, group XVI 0.256925
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.254743
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.25438
CXCL3 chemokine (C-X-C motif) ligand 3 0.253291
DDHD2 DDHD domain containing 2 0.250026
SNX3 sorting nexin 3 0.250026
PTGFRN prostaglandin F2 receptor inhibitor 0.248578
CLC Charcot-Leyden crystal galectin 0.245685
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.243158
PROM1 prominin 1 0.240276
RDH10 retinol dehydrogenase 10 (all-trans) 0.239557
FTH1 ferritin, heavy polypeptide 1 0.238119
ERBB2 erb-b2 receptor tyrosine kinase 2 0.23776
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 0.236324
FN1 fibronectin 1 0.236324
FNTA farnesyltransferase, CAAX box, alpha 0.235966
KRT18 keratin 18, type I 0.234891
ENO2 enolase 2 (gamma, neuronal) 0.234891
MRI1 methylthioribose-1-phosphate isomerase 1 0.232744
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 0.229176
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 0.229176
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 0.228464
LPCAT2 lysophosphatidylcholine acyltransferase 2 0.228464
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.228108
TLR6 toll-like receptor 6 0.227752
LYRM1 LYR motif containing 1 0.225267
PON1 paraoxonase 1 0.224913
AR androgen receptor 0.224558
BMP2 bone morphogenetic protein 2 0.22385
TNF tumor necrosis factor 0.222083
FAR1 fatty acyl CoA reductase 1 0.219265
APOBR apolipoprotein B receptor 0.217511
PHB prohibitin 0.21646
IL6 interleukin 6 0.216111
ADGRL1 adhesion G protein-coupled receptor L1 0.215761
MFGE8 milk fat globule-EGF factor 8 protein 0.215063
ACAN aggrecan 0.213669
F8 coagulation factor VIII, procoagulant component 0.212974
CBY1 chibby homolog 1 (Drosophila) 0.212974
ANXA5 annexin A5 0.211587
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 0.210203
OSBPL9 oxysterol binding protein-like 9 0.209858
G6PD glucose-6-phosphate dehydrogenase 0.209858
INSR insulin receptor 0.207108
PTH parathyroid hormone 0.206423
ITCH itchy E3 ubiquitin protein ligase 0.20574
NT5E 5'-nucleotidase, ecto (CD73) 0.204378
HMGA2 high mobility group AT-hook 2 0.204378
EHD2 EH-domain containing 2 0.204039
MGLL monoglyceride lipase 0.202684
CERK ceramide kinase 0.200663
ADIG adipogenin 0.198658
TMEM53 transmembrane protein 53 0.196999
EPAS1 endothelial PAS domain protein 1 0.194371
THRAP3 thyroid hormone receptor associated protein 3 0.19307
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 0.192423
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.191777
IFITM2 interferon induced transmembrane protein 2 0.191777
RGR retinal G protein coupled receptor 0.191456
CH25H cholesterol 25-hydroxylase 0.191135
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 0.190495
STC1 stanniocalcin 1 0.190175
GJA1 gap junction protein, alpha 1, 43kDa 0.18859
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.186708
MACC1 metastasis associated in colon cancer 1 0.18516
HBA1 hemoglobin, alpha 1 0.184853
EDA ectodysplasin A 0.184547
NANOG Nanog homeobox 0.183631
HMGA1 high mobility group AT-hook 1 0.183025
CPT1A carnitine palmitoyltransferase 1A (liver) 0.18093
WNT10B wingless-type MMTV integration site family, member 10B 0.18093
TP53 tumor protein p53 0.180634
HBA2 hemoglobin, alpha 2 0.180339
TBC1D20 TBC1 domain family, member 20 0.180045
RAB32 RAB32, member RAS oncogene family 0.179459
ATG5 autophagy related 5 0.179167
FTL ferritin, light polypeptide 0.178877
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.178588
ARV1 ARV1 homolog (S. cerevisiae) 0.177439
ICAM1 intercellular adhesion molecule 1 0.177439
CCND1 cyclin D1 0.17687
NR1H3 nuclear receptor subfamily 1, group H, member 3 0.176024
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 0.176024
ISG20 interferon stimulated exonuclease gene 20kDa 0.175745
RGN regucalcin 0.174361
BTNL2 butyrophilin-like 2 0.170888
MAT1A methionine adenosyltransferase I, alpha 0.169859
GJB6 gap junction protein, beta 6, 30kDa 0.167856
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.167611
ACSBG1 acyl-CoA synthetase bubblegum family member 1 0.167611
AANAT aralkylamine N-acetyltransferase 0.167004
HELT helt bHLH transcription factor 0.165231
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.16342
FGF10 fibroblast growth factor 10 0.16309
BECN1 beclin 1, autophagy related 0.161275
SOD1 superoxide dismutase 1, soluble 0.161171
MAPK1 mitogen-activated protein kinase 1 0.159856
ZNF347 zinc finger protein 347 0.158129
DAZAP1 DAZ associated protein 1 0.157943
STARD6 StAR-related lipid transfer (START) domain containing 6 0.156688
MYF5 myogenic factor 5 0.156688
PHB2 prohibitin 2 0.144769
EXO1 exonuclease 1 0.144721
ACP2 acid phosphatase 2, lysosomal 0.144295
PRDX6 peroxiredoxin 6 0.143591
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.143527
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.143015
ELOVL5 ELOVL fatty acid elongase 5 0.142408
GH1 growth hormone 1 0.142055
TPI1 triosephosphate isomerase 1 0.141476
LATS1 large tumor suppressor kinase 1 0.141437
PC pyruvate carboxylase 0.141304
FANCD2 Fanconi anemia, complementation group D2 0.140707
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.140199
SDF4 stromal cell derived factor 4 0.139993
G6PC glucose-6-phosphatase, catalytic subunit 0.138741
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.138529