liothyronine-4947 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the liothyronine-4947 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AHI1 Abelson helper integration site 1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APOLD1 apolipoprotein L domain containing 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
BAIAP3 BAI1-associated protein 3
BMP2K BMP2 inducible kinase
BMP8B bone morphogenetic protein 8b
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMKV CaM kinase-like vesicle-associated
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCR7 chemokine (C-C motif) receptor 7
CFHR4 complement factor H-related 4
CLCN4 chloride channel, voltage-sensitive 4
CLCN7 chloride channel, voltage-sensitive 7
COL1A1 collagen, type I, alpha 1
CRMP1 collapsin response mediator protein 1
CST1 cystatin SN
CXCR4 chemokine (C-X-C motif) receptor 4
CXORF21 chromosome X open reading frame 21
DFNB31 deafness, autosomal recessive 31
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
FAM46C family with sequence similarity 46, member C
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF6 fibroblast growth factor 6
FYB FYN binding protein
GALR3 galanin receptor 3
GLP1R glucagon-like peptide 1 receptor
GOLGA2 golgin A2
GSPT1 G1 to S phase transition 1
HFE hemochromatosis
HGD homogentisate 1,2-dioxygenase
HOXC8 homeobox C8
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
ICAM1 intercellular adhesion molecule 1
IDS iduronate 2-sulfatase
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITGA8 integrin, alpha 8
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KRT19P2 keratin 19 pseudogene 2
LIMCH1 LIM and calponin homology domains 1
LINC00341 long intergenic non-protein coding RNA 341
LMF2 lipase maturation factor 2
LUC7L3 LUC7-like 3 (S. cerevisiae)
MAP1S microtubule-associated protein 1S
MAPK7 mitogen-activated protein kinase 7
MAST3 microtubule associated serine/threonine kinase 3
MCOLN1 mucolipin 1
MED31 mediator complex subunit 31
MINK1 misshapen-like kinase 1
MRPL41 mitochondrial ribosomal protein L41
MTRF1L mitochondrial translational release factor 1-like
MYB v-myb avian myeloblastosis viral oncogene homolog
NF2 neurofibromin 2 (merlin)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRXN2 neurexin 2
OSBPL10 oxysterol binding protein-like 10
PARVA parvin, alpha
PGR progesterone receptor
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLK3 polo-like kinase 3
POPDC3 popeye domain containing 3
PRF1 perforin 1 (pore forming protein)
PURA purine-rich element binding protein A
RAB2A RAB2A, member RAS oncogene family
RBM48 RNA binding motif protein 48
RGS12 regulator of G-protein signaling 12
RIMS3 regulating synaptic membrane exocytosis 3
RPLP2 ribosomal protein, large, P2
S100A7 S100 calcium binding protein A7
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SSTR5 somatostatin receptor 5
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
SUGP1 SURP and G patch domain containing 1
TAPBP TAP binding protein (tapasin)
TCP11L1 t-complex 11, testis-specific-like 1
TMEM19 transmembrane protein 19
TP53I11 tumor protein p53 inducible protein 11
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRD T cell receptor delta locus
TRIM36 tripartite motif containing 36
TRIO trio Rho guanine nucleotide exchange factor
TSPAN2 tetraspanin 2
TTC9 tetratricopeptide repeat domain 9
TTLL5 tubulin tyrosine ligase-like family member 5
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP5 vesicle-associated membrane protein 5
ZBTB17 zinc finger and BTB domain containing 17
ZNF345 zinc finger protein 345
ZNF423 zinc finger protein 423
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMT aminomethyltransferase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAHCC1 BAH domain and coiled-coil containing 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX8 chromobox homolog 8
CCP110 centriolar coiled coil protein 110kDa
CHMP6 charged multivesicular body protein 6
CHPF chondroitin polymerizing factor
CHRM3 cholinergic receptor, muscarinic 3
CISH cytokine inducible SH2-containing protein
COMMD9 COMM domain containing 9
CRYBB2P1 crystallin, beta B2 pseudogene 1
CST6 cystatin E/M
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DSCAM Down syndrome cell adhesion molecule
FAAH fatty acid amide hydrolase
FAM184A family with sequence similarity 184, member A
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GFOD1 glucose-fructose oxidoreductase domain containing 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPRC5C G protein-coupled receptor, class C, group 5, member C
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AL histone cluster 1, H2al
HOXC10 homeobox C10
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFT81 intraflagellar transport 81
INO80B INO80 complex subunit B
INPP5K inositol polyphosphate-5-phosphatase K
ISG15 ISG15 ubiquitin-like modifier
JMJD4 jumonji domain containing 4
KIAA0754 KIAA0754
KRT8P12 keratin 8 pseudogene 12
LIN7B lin-7 homolog B (C. elegans)
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC61 leucine rich repeat containing 61
LRRC8E leucine rich repeat containing 8 family, member E
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
LZTR1 leucine-zipper-like transcription regulator 1
MFAP2 microfibrillar-associated protein 2
MVP major vault protein
NBEAL2 neurobeachin-like 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NPM3 nucleophosmin/nucleoplasmin 3
NRGN neurogranin (protein kinase C substrate, RC3)
OSMR oncostatin M receptor
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PGPEP1 pyroglutamyl-peptidase I
PHC1 polyhomeotic homolog 1 (Drosophila)
PHEX phosphate regulating endopeptidase homolog, X-linked
PLA2G15 phospholipase A2, group XV
PLCD1 phospholipase C, delta 1
PRICKLE3 prickle homolog 3 (Drosophila)
QTRT1 queuine tRNA-ribosyltransferase 1
RNF19B ring finger protein 19B
RPL23AP32 ribosomal protein L23a pseudogene 32
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
STBD1 starch binding domain 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARP TCR gamma alternate reading frame protein
TCTA T-cell leukemia translocation altered
THBS3 thrombospondin 3
TMEM115 transmembrane protein 115
TNRC6B trinucleotide repeat containing 6B
TOM1 target of myb1 (chicken)
TRABD TraB domain containing
TRAPPC6A trafficking protein particle complex 6A
TSPAN14 tetraspanin 14
UPK3B uroplakin 3B
VAV1 vav 1 guanine nucleotide exchange factor
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB48 zinc finger and BTB domain containing 48
ZC3H3 zinc finger CCCH-type containing 3
ZNF276 zinc finger protein 276
ZNF747 zinc finger protein 747
ZNF767P zinc finger family member 767, pseudogene