liothyronine-3324 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the liothyronine-3324 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
AGBL2 ATP/GTP binding protein-like 2
ALDOB aldolase B, fructose-bisphosphate
AMN amnion associated transmembrane protein
ANGPT1 angiopoietin 1
APOL2 apolipoprotein L, 2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARID1A AT rich interactive domain 1A (SWI-like)
ARID5A AT rich interactive domain 5A (MRF1-like)
BAAT bile acid CoA:amino acid N-acyltransferase
C14ORF79 chromosome 14 open reading frame 79
C15ORF39 chromosome 15 open reading frame 39
CALCR calcitonin receptor
CD3D CD3d molecule, delta (CD3-TCR complex)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDK13 cyclin-dependent kinase 13
CEP112 centrosomal protein 112kDa
CIB2 calcium and integrin binding family member 2
CLDN18 claudin 18
COL11A2 collagen, type XI, alpha 2
COL1A2 collagen, type I, alpha 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTSS cathepsin S
DEAF1 DEAF1 transcription factor
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DUSP10 dual specificity phosphatase 10
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHB2 EPH receptor B2
FETUB fetuin B
FKRP fukutin related protein
FN1 fibronectin 1
FOXN3 forkhead box N3
FRAS1 Fraser extracellular matrix complex subunit 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GSN-AS1 GSN antisense RNA 1
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXD11 homeobox D11
HSF2BP heat shock transcription factor 2 binding protein
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IGFBP5 insulin-like growth factor binding protein 5
IL23A interleukin 23, alpha subunit p19
IRF4 interferon regulatory factor 4
IRS4 insulin receptor substrate 4
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
LAG3 lymphocyte-activation gene 3
LTBP4 latent transforming growth factor beta binding protein 4
MAPK14 mitogen-activated protein kinase 14
MBNL2 muscleblind-like splicing regulator 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR622 microRNA 622
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MRPL41 mitochondrial ribosomal protein L41
MUC3B mucin 3B, cell surface associated
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYOZ1 myozenin 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NCF4 neutrophil cytosolic factor 4, 40kDa
NECAB2 N-terminal EF-hand calcium binding protein 2
NME5 NME/NM23 family member 5
NOP16 NOP16 nucleolar protein
NPC1 Niemann-Pick disease, type C1
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRG2 neuregulin 2
ORAI2 ORAI calcium release-activated calcium modulator 2
PDE10A phosphodiesterase 10A
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLXNC1 plexin C1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPARG peroxisome proliferator-activated receptor gamma
RAB6B RAB6B, member RAS oncogene family
RASA3 RAS p21 protein activator 3
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS12 regulator of G-protein signaling 12
RIMS3 regulating synaptic membrane exocytosis 3
RND1 Rho family GTPase 1
SAFB2 scaffold attachment factor B2
SARM1 sterile alpha and TIR motif containing 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STRN striatin, calmodulin binding protein
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAGLN3 transgelin 3
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TCP10L t-complex 10-like
TIGD6 tigger transposable element derived 6
TK2 thymidine kinase 2, mitochondrial
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMPRSS4 transmembrane protease, serine 4
TTC38 tetratricopeptide repeat domain 38
TUBB7P tubulin, beta 7, pseudogene
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
UROD uroporphyrinogen decarboxylase
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALS2CL ALS2 C-terminal like
ANP32A-IT1 ANP32A intronic transcript 1
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAHD1 bromo adjacent homology domain containing 1
BCL2L2 BCL2-like 2
BCORL1 BCL6 corepressor-like 1
BMP4 bone morphogenetic protein 4
C21ORF91 chromosome 21 open reading frame 91
CCDC121 coiled-coil domain containing 121
CCNK cyclin K
CCP110 centriolar coiled coil protein 110kDa
CENPO centromere protein O
CEP97 centrosomal protein 97kDa
CHKB choline kinase beta
CORO7 coronin 7
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DUSP8 dual specificity phosphatase 8
DVL1 dishevelled segment polarity protein 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EXOC6B exocyst complex component 6B
FAM46C family with sequence similarity 46, member C
FAM63A family with sequence similarity 63, member A
FKBP5 FK506 binding protein 5
FOXI1 forkhead box I1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GMPR guanosine monophosphate reductase
GUSBP3 glucuronidase, beta pseudogene 3
HDAC5 histone deacetylase 5
HIST1H1E histone cluster 1, H1e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMHA1 histocompatibility (minor) HA-1
IGFBP6 insulin-like growth factor binding protein 6
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IQSEC2 IQ motif and Sec7 domain 2
IRAK4 interleukin-1 receptor-associated kinase 4
IRX4 iroquois homeobox 4
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JUNB jun B proto-oncogene
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM5C lysine (K)-specific demethylase 5C
KIAA0754 KIAA0754
KIAA0894 KIAA0894 protein
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMBR1L limb development membrane protein 1-like
LMNB1 lamin B1
MYO1D myosin ID
NDE1 nudE neurodevelopment protein 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PAIP2B poly(A) binding protein interacting protein 2B
PCDHA6 protocadherin alpha 6
PCDHA9 protocadherin alpha 9
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PSKH1 protein serine kinase H1
RAB3D RAB3D, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
ROM1 retinal outer segment membrane protein 1
RRAGB Ras-related GTP binding B
SCD5 stearoyl-CoA desaturase 5
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SOX12 SRY (sex determining region Y)-box 12
SRD5A3 steroid 5 alpha-reductase 3
SYBU syntabulin (syntaxin-interacting)
TBC1D2 TBC1 domain family, member 2
TMC5 transmembrane channel-like 5
TMC7 transmembrane channel-like 7
TMEM39B transmembrane protein 39B
TPRA1 transmembrane protein, adipocyte asscociated 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UBQLN4 ubiquilin 4
UBXN6 UBX domain protein 6
UNC119 unc-119 homolog (C. elegans)
UPP1 uridine phosphorylase 1
USP20 ubiquitin specific peptidase 20
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEGFC vascular endothelial growth factor C
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB22 zinc finger and BTB domain containing 22
ZNF35 zinc finger protein 35
ZNF573 zinc finger protein 573
ZSCAN26 zinc finger and SCAN domain containing 26