lineage Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

345 genes co-occuring with the biological term lineage in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACAD9 acyl-CoA dehydrogenase family, member 9
ADGRG1 adhesion G protein-coupled receptor G1
AFF1 AF4/FMR2 family, member 1
AGTR1 angiotensin II receptor, type 1
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AIP aryl hydrocarbon receptor interacting protein
AIRE autoimmune regulator
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANXA5 annexin A5
ARID5B AT rich interactive domain 5B (MRF1-like)
ARX aristaless related homeobox
ASCL1 achaete-scute family bHLH transcription factor 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BASP1 brain abundant, membrane attached signal protein 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL6 B-cell CLL/lymphoma 6
BDKRB2 bradykinin receptor B2
BEX2 brain expressed X-linked 2
BHLHA15 basic helix-loop-helix family, member a15
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BOC BOC cell adhesion associated, oncogene regulated
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C1QBP complement component 1, q subcomponent binding protein
CALHM1 calcium homeostasis modulator 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCK cholecystokinin
CCL24 chemokine (C-C motif) ligand 24
CCL3 chemokine (C-C motif) ligand 3
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD19 CD19 molecule
CD27 CD27 molecule
CD300E CD300e molecule
CD300LB CD300 molecule-like family member b
CD300LD CD300 molecule-like family member d
CD300LF CD300 molecule-like family member f
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CD68 CD68 molecule
CD7 CD7 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD86 CD86 molecule
CD9 CD9 molecule
CDC42 cell division cycle 42
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK1 cyclin-dependent kinase 1
CDK6 cyclin-dependent kinase 6
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDON cell adhesion associated, oncogene regulated
CDX2 caudal type homeobox 2
CDX4 caudal type homeobox 4
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CNR2 cannabinoid receptor 2 (macrophage)
CORT cortistatin
CREBBP CREB binding protein
CRX cone-rod homeobox
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSPG4 chondroitin sulfate proteoglycan 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR1 chemokine (C-X-C motif) receptor 1
DDIT3 DNA-damage-inducible transcript 3
DICER1 dicer 1, ribonuclease type III
DLK1 delta-like 1 homolog (Drosophila)
DLL1 delta-like 1 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DMP1 dentin matrix acidic phosphoprotein 1
EBF1 early B-cell factor 1
EDNRA endothelin receptor type A
EEF1B2 eukaryotic translation elongation factor 1 beta 2
EGF epidermal growth factor
EIF2A eukaryotic translation initiation factor 2A, 65kDa
ELK1 ELK1, member of ETS oncogene family
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV6 ets variant 6
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP7 fatty acid binding protein 7, brain
FCRLA Fc receptor-like A
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FGF4 fibroblast growth factor 4
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FLT4 fms-related tyrosine kinase 4
FOXD3 forkhead box D3
FOXL2 forkhead box L2
FOXN1 forkhead box N1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXP2 forkhead box P2
FOXP3 forkhead box P3
FUS FUS RNA binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GCG glucagon
GFI1B growth factor independent 1B transcription repressor
GH1 growth hormone 1
GHRH growth hormone releasing hormone
GIMAP1 GTPase, IMAP family member 1
GIMAP4 GTPase, IMAP family member 4
GIP gastric inhibitory polypeptide
GJA1 gap junction protein, alpha 1, 43kDa
GMFG glia maturation factor, gamma
GP1BA glycoprotein Ib (platelet), alpha polypeptide
HAND1 heart and neural crest derivatives expressed 1
HBA1 hemoglobin, alpha 1
HBEGF heparin-binding EGF-like growth factor
HCLS1 hematopoietic cell-specific Lyn substrate 1
HDAC3 histone deacetylase 3
HES1 hes family bHLH transcription factor 1
HHEX hematopoietically expressed homeobox
HIST2H4A histone cluster 2, H4a
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HLX H2.0-like homeobox
HMOX1 heme oxygenase 1
HOPX HOP homeobox
HOXA10 homeobox A10
HOXA9 homeobox A9
HOXB4 homeobox B4
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA4 heat shock 70kDa protein 4
HSPA8 heat shock 70kDa protein 8
HSPE1 heat shock 10kDa protein 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL17A interleukin 17A
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
IL7R interleukin 7 receptor
INHBA inhibin, beta A
IRF8 interferon regulatory factor 8
ITGA7 integrin, alpha 7
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAG2 jagged 2
JAK2 Janus kinase 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF1 Kruppel-like factor 1 (erythroid)
KLF4 Kruppel-like factor 4 (gut)
KMT2A lysine (K)-specific methyltransferase 2A
KMT2E lysine (K)-specific methyltransferase 2E
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT5 keratin 5, type II
LAT2 linker for activation of T cells family, member 2
LEF1 lymphoid enhancer-binding factor 1
LIN28B lin-28 homolog B (C. elegans)
LMNA lamin A/C
LST1 leukocyte specific transcript 1
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1 mitogen-activated protein kinase 1
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MCAM melanoma cell adhesion molecule
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MIR106A microRNA 106a
MIR140 microRNA 140
MIR146A microRNA 146a
MIR150 microRNA 150
MIR17 microRNA 17
MIR18B microRNA 18b
MIR196B microRNA 196b
MIR199B microRNA 199b
MIR200C microRNA 200c
MIR221 microRNA 221
MIR223 microRNA 223
MIR23A microRNA 23a
MIR27A microRNA 27a
MIR518B microRNA 518b
MITF microphthalmia-associated transcription factor
MME membrane metallo-endopeptidase
MSX1 msh homeobox 1
MSX2 msh homeobox 2
MT-TI tRNA
MUC4 mucin 4, cell surface associated
MYH9 myosin, heavy chain 9, non-muscle
MYL9 myosin, light chain 9, regulatory
MYT1 myelin transcription factor 1
NANOG Nanog homeobox
NCAM1 neural cell adhesion molecule 1
NELL1 NEL-like 1 (chicken)
NES nestin
NEUROG3 neurogenin 3
NF2 neurofibromin 2 (merlin)
NFIA nuclear factor I/A
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX6-1 NK6 homeobox 1
NLRP7 NLR family, pyrin domain containing 7
NME1 NME/NM23 nucleoside diphosphate kinase 1
NME2 NME/NM23 nucleoside diphosphate kinase 2
NODAL nodal growth differentiation factor
NOTCH1 notch 1
NOTCH2 notch 2
NOV nephroblastoma overexpressed
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR5A1 nuclear receptor subfamily 5, group A, member 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTS neurotensin
OLIG1 oligodendrocyte transcription factor 1
OLIG2 oligodendrocyte lineage transcription factor 2
OSM oncostatin M
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PAX3 paired box 3
PAX5 paired box 5
PAX6 paired box 6
PAX7 paired box 7
PCDH11Y protocadherin 11 Y-linked
PDGFB platelet-derived growth factor beta polypeptide
PDLIM7 PDZ and LIM domain 7 (enigma)
PDPK1 3-phosphoinositide dependent protein kinase 1
PDX1 pancreatic and duodenal homeobox 1
PGLYRP1 peptidoglycan recognition protein 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PLET1 placenta expressed transcript 1
POU1F1 POU class 1 homeobox 1
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PRAME preferentially expressed antigen in melanoma
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
PRL prolactin
PRM2 protamine 2
PRNP prion protein
PROM1 prominin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PYY peptide YY
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae)
RHOA ras homolog family member A
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPS14 ribosomal protein S14
RPS19 ribosomal protein S19
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
SATB1 SATB homeobox 1
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCT secretin
SELL selectin L
SF1 splicing factor 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
SOX1 SRY (sex determining region Y)-box 1
SOX17 SRY (sex determining region Y)-box 17
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SP7 Sp7 transcription factor
SPDEF SAM pointed domain containing ETS transcription factor
SPI1 Spi-1 proto-oncogene
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SRSF2 serine/arginine-rich splicing factor 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
SYK spleen tyrosine kinase
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TBX19 T-box 19
TBX21 T-box 21
TCF3 transcription factor 3
TCF4 transcription factor 4
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THY1 Thy-1 cell surface antigen
TLR2 toll-like receptor 2
TMEM88 transmembrane protein 88
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TP53 tumor protein p53
TP63 tumor protein p63
TRA T cell receptor alpha locus
TRB T cell receptor beta locus
TRD T cell receptor delta locus
TRG T cell receptor gamma locus
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC2 tuberous sclerosis 2
TSHB thyroid stimulating hormone, beta
TWIST1 twist family bHLH transcription factor 1
U2AF1 U2 small nuclear RNA auxiliary factor 1
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UPK2 uroplakin 2
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C
VSX2 visual system homeobox 2
WT1 Wilms tumor 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPO1 exportin 1
YBX1 Y box binding protein 1
YY1 YY1 transcription factor
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB7B zinc finger and BTB domain containing 7B
ZEB1 zinc finger E-box binding homeobox 1
ZFPM1 zinc finger protein, FOG family member 1
ZNF521 zinc finger protein 521