lincomycin-7411 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the lincomycin-7411 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
ANKRD26 ankyrin repeat domain 26
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARHGAP44 Rho GTPase activating protein 44
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
AVPR1A arginine vasopressin receptor 1A
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCORL1 BCL6 corepressor-like 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C11ORF80 chromosome 11 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
CCDC93 coiled-coil domain containing 93
CD79B CD79b molecule, immunoglobulin-associated beta
CD82 CD82 molecule
CDC25A cell division cycle 25A
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CHPF2 chondroitin polymerizing factor 2
CLCN2 chloride channel, voltage-sensitive 2
COL5A1 collagen, type V, alpha 1
COPS8 COP9 signalosome subunit 8
CTAGE5 CTAGE family, member 5
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EFNB3 ephrin-B3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHB2 EPH receptor B2
EXO5 exonuclease 5
FAM65A family with sequence similarity 65, member A
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGFR1 fibroblast growth factor receptor 1
FLT4 fms-related tyrosine kinase 4
GAMT guanidinoacetate N-methyltransferase
GAP43 growth associated protein 43
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GSTCD glutathione S-transferase, C-terminal domain containing
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HFE hemochromatosis
HIST1H2AJ histone cluster 1, H2aj
HLA-DMA major histocompatibility complex, class II, DM alpha
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL4R interleukin 4 receptor
IPO9 importin 9
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM5A lysine (K)-specific demethylase 5A
KREMEN2 kringle containing transmembrane protein 2
LAMB3 laminin, beta 3
LIMK1 LIM domain kinase 1
LINC00339 long intergenic non-protein coding RNA 339
LMNA lamin A/C
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MBOAT7 membrane bound O-acyltransferase domain containing 7
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MERTK MER proto-oncogene, tyrosine kinase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MR1 major histocompatibility complex, class I-related
MYL10 myosin, light chain 10, regulatory
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NADK NAD kinase
NCAPH2 non-SMC condensin II complex, subunit H2
NPFFR1 neuropeptide FF receptor 1
ORAI2 ORAI calcium release-activated calcium modulator 2
PACS1 phosphofurin acidic cluster sorting protein 1
PAQR6 progestin and adipoQ receptor family member VI
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLAGL1 pleiomorphic adenoma gene-like 1
PLIN2 perilipin 2
PORCN porcupine homolog (Drosophila)
PRDX2 peroxiredoxin 2
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PVRL3 poliovirus receptor-related 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNFT2 ring finger protein, transmembrane 2
RPL13P5 ribosomal protein L13 pseudogene 5
SBF1 SET binding factor 1
SLC22A14 solute carrier family 22, member 14
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STAT2 signal transducer and activator of transcription 2, 113kDa
STK17B serine/threonine kinase 17b
SYNGR1 synaptogyrin 1
TBX19 T-box 19
THBD thrombomodulin
TRIP11 thyroid hormone receptor interactor 11
TTC9 tetratricopeptide repeat domain 9
TTLL5 tubulin tyrosine ligase-like family member 5
TUBG2 tubulin, gamma 2
TXNRD2 thioredoxin reductase 2
XK X-linked Kx blood group
ZC3H13 zinc finger CCCH-type containing 13
ZNF202 zinc finger protein 202
ZNF609 zinc finger protein 609
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AKR1C3 aldo-keto reductase family 1, member C3
ANKRD28 ankyrin repeat domain 28
ANXA1 annexin A1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BEX4 brain expressed, X-linked 4
BTBD2 BTB (POZ) domain containing 2
CBX8 chromobox homolog 8
CCDC9 coiled-coil domain containing 9
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CGREF1 cell growth regulator with EF-hand domain 1
CINP cyclin-dependent kinase 2 interacting protein
CIR1 corepressor interacting with RBPJ, 1
CISH cytokine inducible SH2-containing protein
COBL cordon-bleu WH2 repeat protein
COL4A5 collagen, type IV, alpha 5
CRYZL1 crystallin, zeta (quinone reductase)-like 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAL4 dynein, axonemal, light chain 4
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EDC3 enhancer of mRNA decapping 3
ERO1L ERO1-like (S. cerevisiae)
FAN1 FANCD2/FANCI-associated nuclease 1
FBXO46 F-box protein 46
FOXC1 forkhead box C1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GAB2 GRB2-associated binding protein 2
HIST1H2BE histone cluster 1, H2be
HOXC11 homeobox C11
IPO8 importin 8
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
KRT13 keratin 13, type I
LHFPL2 lipoma HMGIC fusion partner-like 2
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRRC49 leucine rich repeat containing 49
MAN2B2 mannosidase, alpha, class 2B, member 2
MARC1 mitochondrial amidoxime reducing component 1
MYO1E myosin IE
MYO9A myosin IXA
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDRG4 NDRG family member 4
NR1H3 nuclear receptor subfamily 1, group H, member 3
OGFRL1 opioid growth factor receptor-like 1
OLFML3 olfactomedin-like 3
PANX1 pannexin 1
PARD6A par-6 family cell polarity regulator alpha
PCDHB3 protocadherin beta 3
PECR peroxisomal trans-2-enoyl-CoA reductase
PEX26 peroxisomal biogenesis factor 26
PGPEP1 pyroglutamyl-peptidase I
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PODXL podocalyxin-like
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRICKLE3 prickle homolog 3 (Drosophila)
PRMT7 protein arginine methyltransferase 7
PRR3 proline rich 3
RAB23 RAB23, member RAS oncogene family
RCOR3 REST corepressor 3
REPS2 RALBP1 associated Eps domain containing 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF123 ring finger protein 123
RP2 retinitis pigmentosa 2 (X-linked recessive)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SGK1 serum/glucocorticoid regulated kinase 1
SH2B3 SH2B adaptor protein 3
SH2D4A SH2 domain containing 4A
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMA4 glucuronidase, beta pseudogene
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
TBC1D17 TBC1 domain family, member 17
TET3 tet methylcytosine dioxygenase 3
TFF3 trefoil factor 3 (intestinal)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM209 transmembrane protein 209
TPST1 tyrosylprotein sulfotransferase 1
TUBA3C tubulin, alpha 3c
TUBGCP5 tubulin, gamma complex associated protein 5
TWF2 twinfilin actin binding protein 2
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
URGCP upregulator of cell proliferation
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VAV1 vav 1 guanine nucleotide exchange factor
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZBED8 zinc finger, BED-type containing 8
ZNF180 zinc finger protein 180
ZNF365 zinc finger protein 365
ZNF8 zinc finger protein 8