lewis lung carcinoma cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A cell of a carcinoma discovered by dr. Margaret r. Lewis of the wistar institute in 1951. This tumour originated spontaneously as a carcinoma of the lung of a c57bl mouse. The tumour does not appear to be grossly haemorrhagic and the majority of the tumour tissue is a semifirm homogeneous mass. It is also called 3ll and llc and is used as a transplantable malignancy. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000745)
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Genes

155 proteins co-occuring with the tissue lewis lung carcinoma cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
C20ORF85 chromosome 20 open reading frame 85 1.64506
COL18A1 collagen, type XVIII, alpha 1 1.24699
TPPP3 tubulin polymerization-promoting protein family member 3 1.139
PLAU plasminogen activator, urokinase 1.11774
VASH1 vasohibin 1 1.09695
VEGFA vascular endothelial growth factor A 1.06426
E2F7 E2F transcription factor 7 0.89732
DESI2 desumoylating isopeptidase 2 0.858837
MMP9 matrix metallopeptidase 9 0.843286
GAL3ST1 galactose-3-O-sulfotransferase 1 0.838672
MMP2 matrix metallopeptidase 2 0.832804
RPS7 ribosomal protein S7 0.831966
FGF2 fibroblast growth factor 2 (basic) 0.821085
UBR2 ubiquitin protein ligase E3 component n-recognin 2 0.806465
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.804378
PLG plasminogen 0.787299
VEGFC vascular endothelial growth factor C 0.766539
CHIA chitinase, acidic 0.757432
PMM1 phosphomannomutase 1 0.752057
HSPB6 heat shock protein, alpha-crystallin-related, B6 0.7335
CTSB cathepsin B 0.723631
MANEA mannosidase, endo-alpha 0.722809
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.720345
CASS4 Cas scaffolding protein family member 4 0.679025
CST2 cystatin SA 0.676987
MRPS7 mitochondrial ribosomal protein S7 0.6721
GPR176 G protein-coupled receptor 176 0.66071
KDR kinase insert domain receptor 0.61578
CST1 cystatin SN 0.611346
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.608124
PCSK5 proprotein convertase subtilisin/kexin type 5 0.596058
ANO2 anoctamin 2, calcium activated chloride channel 0.584823
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.571219
FLT1 fms-related tyrosine kinase 1 0.565232
BMPER BMP binding endothelial regulator 0.564833
FN1 fibronectin 1 0.564035
TIMP2 TIMP metallopeptidase inhibitor 2 0.561644
PTGES prostaglandin E synthase 0.555671
YME1L1 YME1-like 1 ATPase 0.536625
GLRA2 glycine receptor, alpha 2 0.533065
ZNF347 zinc finger protein 347 0.523194
PARP1 poly (ADP-ribose) polymerase 1 0.517284
HBA1 hemoglobin, alpha 1 0.508242
CCL2 chemokine (C-C motif) ligand 2 0.506279
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.501574
RGMA repulsive guidance molecule family member a 0.50079
PGF placental growth factor 0.498832
HBA2 hemoglobin, alpha 2 0.495701
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.494136
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.490619
TPPP tubulin polymerization promoting protein 0.488276
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.487106
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.484376
DUSP5 dual specificity phosphatase 5 0.470375
AGER advanced glycosylation end product-specific receptor 0.466885
ERAP1 endoplasmic reticulum aminopeptidase 1 0.448346
COL4A2 collagen, type IV, alpha 2 0.444884
ALDOC aldolase C, fructose-bisphosphate 0.429547
PXN paxillin 0.420766
ALDOB aldolase B, fructose-bisphosphate 0.419623
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 0.415434
HBEGF heparin-binding EGF-like growth factor 0.412011
IDO1 indoleamine 2,3-dioxygenase 1 0.412011
ANXA5 annexin A5 0.41087
ANGPT1 angiopoietin 1 0.408212
BAX BCL2-associated X protein 0.406315
MDK midkine (neurite growth-promoting factor 2) 0.402523
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.397222
IL2 interleukin 2 0.394197
IRAK3 interleukin-1 receptor-associated kinase 3 0.381755
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.374243
CORIN corin, serine peptidase 0.36825
ALDOA aldolase A, fructose-bisphosphate 0.360036
TOP1 topoisomerase (DNA) I 0.351114
DNTT DNA nucleotidylexotransferase 0.348519
S100A4 S100 calcium binding protein A4 0.344079
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.340019
RING1 ring finger protein 1 0.3356
TOP2B topoisomerase (DNA) II beta 180kDa 0.333763
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.333396
C19ORF48 chromosome 19 open reading frame 48 0.32497
UCN2 urocortin 2 0.322414
UGCG UDP-glucose ceramide glucosyltransferase 0.320591
EPHA7 EPH receptor A7 0.315498
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 0.314772
KNTC1 kinetochore associated 1 0.310421
AREG amphiregulin 0.302478
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.29996
HMGA2 high mobility group AT-hook 2 0.289582
ANXA2 annexin A2 0.288514
CELA1 chymotrypsin-like elastase family, member 1 0.287092
FPGS folylpolyglutamate synthase 0.275094
GABARAP GABA(A) receptor-associated protein 0.271604
ANGPT2 angiopoietin 2 0.270909
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.267446
JUNB jun B proto-oncogene 0.264696
CD44 CD44 molecule (Indian blood group) 0.261284
AGTR1 angiotensin II receptor, type 1 0.259929
CELA3B chymotrypsin-like elastase family, member 3B 0.259254
IL6 interleukin 6 0.257572
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.255567
PPP6C protein phosphatase 6, catalytic subunit 0.25259
PROM1 prominin 1 0.247719
PPP5C protein phosphatase 5, catalytic subunit 0.245807
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.24486
TPM2 tropomyosin 2 (beta) 0.242054
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.241746
MSTN myostatin 0.240216
BIRC5 baculoviral IAP repeat containing 5 0.23961
CALR calreticulin 0.238406
CIB1 calcium and integrin binding 1 (calmyrin) 0.237513
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.233162
CXCL12 chemokine (C-X-C motif) ligand 12 0.231206
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.229568
LHX3 LIM homeobox 3 0.226411
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.225144
CD34 CD34 molecule 0.223177
KIN Kin17 DNA and RNA binding protein 0.222978
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.222224
JUN jun proto-oncogene 0.216126
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.215147
PRODH proline dehydrogenase (oxidase) 1 0.213471
LPAR3 lysophosphatidic acid receptor 3 0.200361
LAG3 lymphocyte-activation gene 3 0.20019
DHFR dihydrofolate reductase 0.198871
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 0.197595
DEFB4A defensin, beta 4A 0.197588
MUT methylmalonyl CoA mutase 0.196191
MGAT4C MGAT4 family, member C 0.196064
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.195317
AQP4 aquaporin 4 0.193473
VSIG4 V-set and immunoglobulin domain containing 4 0.19305
HLA-B major histocompatibility complex, class I, B 0.192752
LTF lactotransferrin 0.190238
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.189531
TNF tumor necrosis factor 0.187929
CXCR3 chemokine (C-X-C motif) receptor 3 0.18788
C5AR1 complement component 5a receptor 1 0.186271
MUC1 mucin 1, cell surface associated 0.186034
RPSA ribosomal protein SA 0.184247
GPR162 G protein-coupled receptor 162 0.18287
CD83 CD83 molecule 0.178224
BIRC2 baculoviral IAP repeat containing 2 0.177182
HSPA4 heat shock 70kDa protein 4 0.175371
HSPA1A heat shock 70kDa protein 1A 0.172631
DICER1 dicer 1, ribonuclease type III 0.172479
RICTOR RPTOR independent companion of MTOR, complex 2 0.170799
PER2 period circadian clock 2 0.164836
LGALS3 lectin, galactoside-binding, soluble, 3 0.160921
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.160002
ALK anaplastic lymphoma receptor tyrosine kinase 0.159822
CD4 CD4 molecule 0.157883
SYK spleen tyrosine kinase 0.156022
SMAD3 SMAD family member 3 0.154841
IGF1R insulin-like growth factor 1 receptor 0.146704