levomepromazine-7399 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the levomepromazine-7399 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACE angiotensin I converting enzyme
AIM2 absent in melanoma 2
ANKMY1 ankyrin repeat and MYND domain containing 1
APOC1 apolipoprotein C-I
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
BDKRB1 bradykinin receptor B1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CBX2 chromobox homolog 2
CCL21 chemokine (C-C motif) ligand 21
CCNG2 cyclin G2
CCNJ cyclin J
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC1A C-type lectin domain family 1, member A
CLTA clathrin, light chain A
COPE coatomer protein complex, subunit epsilon
CSHL1 chorionic somatomammotropin hormone-like 1
CTNND2 catenin (cadherin-associated protein), delta 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDIT3 DNA-damage-inducible transcript 3
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DPP4 dipeptidyl-peptidase 4
DPYSL4 dihydropyrimidinase-like 4
DRP2 dystrophin related protein 2
EFNA3 ephrin-A3
ELL elongation factor RNA polymerase II
ERO1LB ERO1-like beta (S. cerevisiae)
FAM186A family with sequence similarity 186, member A
FGFR1 fibroblast growth factor receptor 1
FOXL1 forkhead box L1
FYB FYN binding protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAB1 GRB2-associated binding protein 1
GOLGA2 golgin A2
GRTP1 growth hormone regulated TBC protein 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
ICAM1 intercellular adhesion molecule 1
INSIG1 insulin induced gene 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KLF13 Kruppel-like factor 13
KLHL24 kelch-like family member 24
KLHL28 kelch-like family member 28
KLHL29 kelch-like family member 29
KLHL4 kelch-like family member 4
KRT33A keratin 33A, type I
LINC00597 long intergenic non-protein coding RNA 597
LMNA lamin A/C
LRRC23 leucine rich repeat containing 23
LRRK1 leucine-rich repeat kinase 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MPPE1 metallophosphoesterase 1
MYLIP myosin regulatory light chain interacting protein
MYO15A myosin XVA
MYOZ3 myozenin 3
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NUPR1 nuclear protein, transcriptional regulator, 1
ORC5 origin recognition complex, subunit 5
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PER1 period circadian clock 1
PLSCR4 phospholipid scramblase 4
POMT2 protein-O-mannosyltransferase 2
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PTPN2 protein tyrosine phosphatase, non-receptor type 2
QPCTL glutaminyl-peptide cyclotransferase-like
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS14 regulator of G-protein signaling 14
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SERHL2 serine hydrolase-like 2
SIDT2 SID1 transmembrane family, member 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
SQSTM1 sequestosome 1
STARD3 StAR-related lipid transfer (START) domain containing 3
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
SYT13 synaptotagmin XIII
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D30 TBC1 domain family, member 30
TESK2 testis-specific kinase 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNK1 tyrosine kinase, non-receptor, 1
TRIB3 tribbles pseudokinase 3
TRIM23 tripartite motif containing 23
TSC22D2 TSC22 domain family, member 2
VCL vinculin
ZFHX3 zinc finger homeobox 3
ZNF277 zinc finger protein 277
ZNF592 zinc finger protein 592

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRF1 adhesion G protein-coupled receptor F1
AGMAT agmatine ureohydrolase (agmatinase)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ASB6 ankyrin repeat and SOCS box containing 6
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCAS3 breast carcinoma amplified sequence 3
BGLAP bone gamma-carboxyglutamate (gla) protein
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1ORF159 chromosome 1 open reading frame 159
CA5BP1 carbonic anhydrase VB pseudogene 1
CCDC176 coiled-coil domain containing 176
CCS copper chaperone for superoxide dismutase
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK3 cyclin-dependent kinase 3
CENPJ centromere protein J
CFAP69 cilia and flagella associated protein 69
CHST10 carbohydrate sulfotransferase 10
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLEC16A C-type lectin domain family 16, member A
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DENND5B DENN/MADD domain containing 5B
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNA2 DNA replication helicase/nuclease 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ERAP2 endoplasmic reticulum aminopeptidase 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETAA1 Ewing tumor-associated antigen 1
ETNK2 ethanolamine kinase 2
EYA3 EYA transcriptional coactivator and phosphatase 3
F3 coagulation factor III (thromboplastin, tissue factor)
FAM160B2 family with sequence similarity 160, member B2
GPRASP1 G protein-coupled receptor associated sorting protein 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HHLA3 HERV-H LTR-associating 3
HIST1H2BJ histone cluster 1, H2bj
HIST1H3C histone cluster 1, H3c
HOXC8 homeobox C8
IL4R interleukin 4 receptor
INCENP inner centromere protein antigens 135/155kDa
KIAA0556 KIAA0556
KIAA1462 KIAA1462
KLHL36 kelch-like family member 36
KRT6A keratin 6A, type II
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC61 leucine rich repeat containing 61
LUC7L LUC7-like (S. cerevisiae)
MAST3 microtubule associated serine/threonine kinase 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCRS1 microspherule protein 1
MOCS3 molybdenum cofactor synthesis 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTCL1 microtubule crosslinking factor 1
MYL5 myosin, light chain 5, regulatory
NDE1 nudE neurodevelopment protein 1
NOL6 nucleolar protein 6 (RNA-associated)
NR1H3 nuclear receptor subfamily 1, group H, member 3
NT5M 5',3'-nucleotidase, mitochondrial
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARPBP PARP1 binding protein
PTK7 protein tyrosine kinase 7 (inactive)
RARS arginyl-tRNA synthetase
RFWD3 ring finger and WD repeat domain 3
RGS17 regulator of G-protein signaling 17
RIN1 Ras and Rab interactor 1
RNF2 ring finger protein 2
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SIDT1 SID1 transmembrane family, member 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SNIP1 Smad nuclear interacting protein 1
SPRYD7 SPRY domain containing 7
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST5 suppression of tumorigenicity 5
SYNPO synaptopodin
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM132A transmembrane protein 132A
TMEM8B transmembrane protein 8B
TSPAN2 tetraspanin 2
TWISTNB TWIST neighbor
TXLNG taxilin gamma
UGT8 UDP glycosyltransferase 8
VGF VGF nerve growth factor inducible
WBSCR16 Williams-Beuren syndrome chromosome region 16
WDR4 WD repeat domain 4
YOD1 YOD1 deubiquitinase
ZNF10 zinc finger protein 10
ZNF215 zinc finger protein 215
ZNF280D zinc finger protein 280D
ZNF671 zinc finger protein 671