levocabastine-7249 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the levocabastine-7249 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANP32A-IT1 ANP32A intronic transcript 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGAP11A Rho GTPase activating protein 11A
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATP9B ATPase, class II, type 9B
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
BAX BCL2-associated X protein
BRWD1 bromodomain and WD repeat domain containing 1
BSPRY B-box and SPRY domain containing
C10ORF88 chromosome 10 open reading frame 88
CABIN1 calcineurin binding protein 1
CHM choroideremia (Rab escort protein 1)
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
DAZAP2 DAZ associated protein 2
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DST dystonin
EML3 echinoderm microtubule associated protein like 3
FBN2 fibrillin 2
FGFR1 fibroblast growth factor receptor 1
FOXO1 forkhead box O1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GPALPP1 GPALPP motifs containing 1
HIST1H2BM histone cluster 1, H2bm
HOXC10 homeobox C10
IFNA14 interferon, alpha 14
IL12RB1 interleukin 12 receptor, beta 1
IL17RA interleukin 17 receptor A
KIAA1109 KIAA1109
KMT2A lysine (K)-specific methyltransferase 2A
KRIT1 KRIT1, ankyrin repeat containing
LDB1 LIM domain binding 1
LRP1 low density lipoprotein receptor-related protein 1
MAPK7 mitogen-activated protein kinase 7
MED23 mediator complex subunit 23
MKL1 megakaryoblastic leukemia (translocation) 1
MLH3 mutL homolog 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MPHOSPH9 M-phase phosphoprotein 9
MTAP methylthioadenosine phosphorylase
MUC1 mucin 1, cell surface associated
MX1 MX dynamin-like GTPase 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NF1 neurofibromin 1
NFX1 nuclear transcription factor, X-box binding 1
NMT2 N-myristoyltransferase 2
NOVA1 neuro-oncological ventral antigen 1
NRXN3 neurexin 3
NT5M 5',3'-nucleotidase, mitochondrial
NXPE3 neurexophilin and PC-esterase domain family, member 3
NYNRIN NYN domain and retroviral integrase containing
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PCBP2 poly(rC) binding protein 2
PGAP1 post-GPI attachment to proteins 1
PIDD1 p53-induced death domain protein 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLXNB3 plexin B3
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRR7 proline rich 7 (synaptic)
RFK riboflavin kinase
RHOBTB2 Rho-related BTB domain containing 2
RNASEH2B ribonuclease H2, subunit B
RNF219 ring finger protein 219
ROGDI rogdi homolog (Drosophila)
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RUSC2 RUN and SH3 domain containing 2
SAPCD1 suppressor APC domain containing 1
SERHL2 serine hydrolase-like 2
SETD6 SET domain containing 6
SIDT2 SID1 transmembrane family, member 2
SLC17A2 solute carrier family 17, member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPATA5L1 spermatogenesis associated 5-like 1
STARD5 StAR-related lipid transfer (START) domain containing 5
TAZ tafazzin
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TBCD tubulin folding cofactor D
TCP11 t-complex 11, testis-specific
TDRD3 tudor domain containing 3
TEF thyrotrophic embryonic factor
TENM1 teneurin transmembrane protein 1
TESK2 testis-specific kinase 2
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TMCO6 transmembrane and coiled-coil domains 6
TMEM231 transmembrane protein 231
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TPD52L1 tumor protein D52-like 1
TRIM23 tripartite motif containing 23
TTC33 tetratricopeptide repeat domain 33
TTC37 tetratricopeptide repeat domain 37
TTLL7 tubulin tyrosine ligase-like family member 7
UNC45A unc-45 homolog A (C. elegans)
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZBTB14 zinc finger and BTB domain containing 14
ZBTB7A zinc finger and BTB domain containing 7A
ZC3H7B zinc finger CCCH-type containing 7B
ZMYM5 zinc finger, MYM-type 5
ZNF189 zinc finger protein 189

decreased expression

Symbol Name
AEN apoptosis enhancing nuclease
ANKRD40 ankyrin repeat domain 40
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P3 annexin A2 pseudogene 3
APLP1 amyloid beta (A4) precursor-like protein 1
ASB7 ankyrin repeat and SOCS box containing 7
ASCC2 activating signal cointegrator 1 complex subunit 2
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BLMH bleomycin hydrolase
BRD1 bromodomain containing 1
BRIX1 BRX1, biogenesis of ribosomes
BTBD2 BTB (POZ) domain containing 2
C11ORF73 chromosome 11 open reading frame 73
C1R complement component 1, r subcomponent
C4ORF19 chromosome 4 open reading frame 19
C8ORF60 chromosome 8 open reading frame 60
CCDC101 coiled-coil domain containing 101
CCDC88C coiled-coil domain containing 88C
CENPT centromere protein T
CHML choroideremia-like (Rab escort protein 2)
CRIP2 cysteine-rich protein 2
DBF4B DBF4 zinc finger B
DEAF1 DEAF1 transcription factor
DSPP dentin sialophosphoprotein
DTWD1 DTW domain containing 1
FAM102A family with sequence similarity 102, member A
FBXO46 F-box protein 46
FKBPL FK506 binding protein like
FXN frataxin
GPATCH3 G patch domain containing 3
GPRASP1 G protein-coupled receptor associated sorting protein 1
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KATNBL1 katanin p80 subunit B-like 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
LMBR1L limb development membrane protein 1-like
MAGEF1 melanoma antigen family F1
MED22 mediator complex subunit 22
MFSD12 major facilitator superfamily domain containing 12
NECAP2 NECAP endocytosis associated 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
NSD1 nuclear receptor binding SET domain protein 1
NUPL2 nucleoporin like 2
OGFRL1 opioid growth factor receptor-like 1
OSBP2 oxysterol binding protein 2
OSMR oncostatin M receptor
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PALMD palmdelphin
PCBP4 poly(rC) binding protein 4
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PNRC1 proline-rich nuclear receptor coactivator 1
RAB17 RAB17, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RGS20 regulator of G-protein signaling 20
RNF25 ring finger protein 25
RPGR retinitis pigmentosa GTPase regulator
RPP38 ribonuclease P/MRP 38kDa subunit
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RRP1 ribosomal RNA processing 1
S100A9 S100 calcium binding protein A9
SETMAR SET domain and mariner transposase fusion gene
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNX15 sorting nexin 15
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STBD1 starch binding domain 1
SUGCT succinyl-CoA:glutarate-CoA transferase
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYTL2 synaptotagmin-like 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCTN2 tectonic family member 2
TIGD6 tigger transposable element derived 6
TM7SF2 transmembrane 7 superfamily member 2
TMEM209 transmembrane protein 209
TMEM57 transmembrane protein 57
TNS2 tensin 2
TRIM21 tripartite motif containing 21
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZFP69B ZFP69 zinc finger protein B
ZNF14 zinc finger protein 14
ZNF230 zinc finger protein 230
ZNF273 zinc finger protein 273
ZNF444 zinc finger protein 444
ZNF669 zinc finger protein 669