levocabastine-7009 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the levocabastine-7009 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ADAM23 ADAM metallopeptidase domain 23
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AIM1L absent in melanoma 1-like
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
C7ORF43 chromosome 7 open reading frame 43
CADM3 cell adhesion molecule 3
CC2D1A coiled-coil and C2 domain containing 1A
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCPG1 cell cycle progression 1
CHD3 chromodomain helicase DNA binding protein 3
CHST10 carbohydrate sulfotransferase 10
CLASP2 cytoplasmic linker associated protein 2
CTSK cathepsin K
CUZD1 CUB and zona pellucida-like domains 1
DIXDC1 DIX domain containing 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
FAAH fatty acid amide hydrolase
FAM198B family with sequence similarity 198, member B
FAM212B family with sequence similarity 212, member B
FAM63A family with sequence similarity 63, member A
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF6 fibroblast growth factor 6
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GADD45B growth arrest and DNA-damage-inducible, beta
GJB3 gap junction protein, beta 3, 31kDa
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GOSR2 golgi SNAP receptor complex member 2
GSAP gamma-secretase activating protein
HDAC4 histone deacetylase 4
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
IDS iduronate 2-sulfatase
IL11 interleukin 11
ING4 inhibitor of growth family, member 4
IPO8 importin 8
ITM2C integral membrane protein 2C
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0141 KIAA0141
KLK5 kallikrein-related peptidase 5
KREMEN2 kringle containing transmembrane protein 2
KRT6B keratin 6B, type II
LHX6 LIM homeobox 6
LOC642236 FSHD region gene 1 pseudogene
LRRC40 leucine rich repeat containing 40
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP4 microtubule-associated protein 4
MCM3AP minichromosome maintenance complex component 3 associated protein
MEGF9 multiple EGF-like-domains 9
MFAP3L microfibrillar-associated protein 3-like
OTUD3 OTU deubiquitinase 3
PAWR PRKC, apoptosis, WT1, regulator
PCDHB13 protocadherin beta 13
PDGFA platelet-derived growth factor alpha polypeptide
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PITX1 paired-like homeodomain 1
PKNOX1 PBX/knotted 1 homeobox 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLCD1 phospholipase C, delta 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLTP phospholipid transfer protein
POLG polymerase (DNA directed), gamma
PRAMEF11 PRAME family member 11
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS53 protease, serine, 53
RAP2B RAP2B, member of RAS oncogene family
RPGR retinitis pigmentosa GTPase regulator
RSL1D1 ribosomal L1 domain containing 1
SCRN3 secernin 3
SETD4 SET domain containing 4
SFXN3 sideroflexin 3
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLMO1 slowmo homolog 1 (Drosophila)
SPAG4 sperm associated antigen 4
STAT5B signal transducer and activator of transcription 5B
STBD1 starch binding domain 1
STYK1 serine/threonine/tyrosine kinase 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAZ tafazzin
TCL1B T-cell leukemia/lymphoma 1B
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM2D1 TM2 domain containing 1
TMCO3 transmembrane and coiled-coil domains 3
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TRD T cell receptor delta locus
TUBA3C tubulin, alpha 3c
TWF1 twinfilin actin binding protein 1
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
USP22 ubiquitin specific peptidase 22
WBP2 WW domain binding protein 2
ZBTB14 zinc finger and BTB domain containing 14
ZNF324 zinc finger protein 324
ZNF576 zinc finger protein 576

decreased expression

Symbol Name
ADCK3 aarF domain containing kinase 3
AKR1C3 aldo-keto reductase family 1, member C3
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANXA1 annexin A1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHD1 bromo adjacent homology domain containing 1
BATF basic leucine zipper transcription factor, ATF-like
BMP4 bone morphogenetic protein 4
C14ORF132 chromosome 14 open reading frame 132
C19ORF54 chromosome 19 open reading frame 54
C5ORF45 chromosome 5 open reading frame 45
CAMTA2 calmodulin binding transcription activator 2
CEP85 centrosomal protein 85kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLSPN claspin
CREB3L2 cAMP responsive element binding protein 3-like 2
CSAD cysteine sulfinic acid decarboxylase
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUEDC1 CUE domain containing 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGKZ diacylglycerol kinase, zeta
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
FA2H fatty acid 2-hydroxylase
FAM192A family with sequence similarity 192, member A
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FUZ fuzzy planar cell polarity protein
GAB2 GRB2-associated binding protein 2
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GAREM GRB2 associated, regulator of MAPK1
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCC1 GRIP and coiled-coil domain containing 1
GLB1L2 galactosidase, beta 1-like 2
GTPBP2 GTP binding protein 2
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BI histone cluster 1, H2bi
INF2 inverted formin, FH2 and WH2 domain containing
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF9 interferon regulatory factor 9
ITPKC inositol-trisphosphate 3-kinase C
JMJD1C jumonji domain containing 1C
KCNK15 potassium channel, two pore domain subfamily K, member 15
KRT8P12 keratin 8 pseudogene 12
LAMA3 laminin, alpha 3
LHFPL2 lipoma HMGIC fusion partner-like 2
LMCD1 LIM and cysteine-rich domains 1
LRP3 low density lipoprotein receptor-related protein 3
LRRC49 leucine rich repeat containing 49
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MBOAT2 membrane bound O-acyltransferase domain containing 2
METTL16 methyltransferase like 16
METTL21B methyltransferase like 21B
MFSD12 major facilitator superfamily domain containing 12
MTCL1 microtubule crosslinking factor 1
MYL5 myosin, light chain 5, regulatory
NBEAL2 neurobeachin-like 2
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NES nestin
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NINL ninein-like
NKAIN1 Na+/K+ transporting ATPase interacting 1
OLFML3 olfactomedin-like 3
PPP1R26 protein phosphatase 1, regulatory subunit 26
RANGRF RAN guanine nucleotide release factor
RFTN1 raftlin, lipid raft linker 1
RNF31 ring finger protein 31
RPL13P5 ribosomal protein L13 pseudogene 5
SCAMP4 secretory carrier membrane protein 4
SECISBP2 SECIS binding protein 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
TESK2 testis-specific kinase 2
TNRC6B trinucleotide repeat containing 6B
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRIM5 tripartite motif containing 5
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3D tubulin, alpha 3d
TWF2 twinfilin actin binding protein 2
ULBP2 UL16 binding protein 2
WDR37 WD repeat domain 37
WDR4 WD repeat domain 4
YEATS2 YEATS domain containing 2
YEATS4 YEATS domain containing 4
ZC3H3 zinc finger CCCH-type containing 3
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF143 zinc finger protein 143
ZNF276 zinc finger protein 276
ZNF586 zinc finger protein 586
ZNF654 zinc finger protein 654
ZNHIT2 zinc finger, HIT-type containing 2