levcycloserine-3870 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the levcycloserine-3870 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRB1 adhesion G protein-coupled receptor B1
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALCAM activated leukocyte cell adhesion molecule
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
BAX BCL2-associated X protein
BCL2L10 BCL2-like 10 (apoptosis facilitator)
C10ORF12 chromosome 10 open reading frame 12
C10ORF95 chromosome 10 open reading frame 95
C17ORF53 chromosome 17 open reading frame 53
C4BPA complement component 4 binding protein, alpha
C6ORF15 chromosome 6 open reading frame 15
CEP295 centrosomal protein 295kDa
CEP41 centrosomal protein 41kDa
CFAP45 cilia and flagella associated protein 45
CLCN7 chloride channel, voltage-sensitive 7
CNGB3 cyclic nucleotide gated channel beta 3
CRAT carnitine O-acetyltransferase
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSF1 colony stimulating factor 1 (macrophage)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DAPK2 death-associated protein kinase 2
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DRD2 dopamine receptor D2
ECM1 extracellular matrix protein 1
EFNA2 ephrin-A2
EFNB3 ephrin-B3
EPX eosinophil peroxidase
EVA1B eva-1 homolog B (C. elegans)
F11 coagulation factor XI
FHIT fragile histidine triad
FRAS1 Fraser extracellular matrix complex subunit 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GRM1 glutamate receptor, metabotropic 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HOXA4 homeobox A4
IFNA17 interferon, alpha 17
IZUMO4 IZUMO family member 4
JUN jun proto-oncogene
KAT6A K(lysine) acetyltransferase 6A
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LRRC1 leucine rich repeat containing 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPT microtubule-associated protein tau
MMP11 matrix metallopeptidase 11
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MOB3B MOB kinase activator 3B
MORN1 MORN repeat containing 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYO15B myosin XVB
NCOA2 nuclear receptor coactivator 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NF1 neurofibromin 1
NPAS2 neuronal PAS domain protein 2
NRDE2 NRDE-2, necessary for RNA interference, domain containing
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PACS1 phosphofurin acidic cluster sorting protein 1
PAQR5 progestin and adipoQ receptor family member V
PARP3 poly (ADP-ribose) polymerase family, member 3
PARVB parvin, beta
PEX6 peroxisomal biogenesis factor 6
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
POFUT1 protein O-fucosyltransferase 1
POU5F1B POU class 5 homeobox 1B
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRLH prolactin releasing hormone
PRPF18 pre-mRNA processing factor 18
PURA purine-rich element binding protein A
RGS12 regulator of G-protein signaling 12
RHBDL1 rhomboid, veinlet-like 1 (Drosophila)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL35A ribosomal protein L35a
RUFY3 RUN and FYVE domain containing 3
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SH3BP2 SH3-domain binding protein 2
SH3GL3 SH3-domain GRB2-like 3
SIRT5 sirtuin 5
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
STX7 syntaxin 7
SUN1 Sad1 and UNC84 domain containing 1
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
TAPBP TAP binding protein (tapasin)
THBS1 thrombospondin 1
THSD4 thrombospondin, type I, domain containing 4
TIMELESS timeless circadian clock
TRIB2 tribbles pseudokinase 2
TUBA4B tubulin, alpha 4b
UMPS uridine monophosphate synthetase
VN1R1 vomeronasal 1 receptor 1
WDFY3 WD repeat and FYVE domain containing 3
WNT5A wingless-type MMTV integration site family, member 5A
ZBTB33 zinc finger and BTB domain containing 33
ZFP2 ZFP2 zinc finger protein
ZNF304 zinc finger protein 304
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAP1 ArfGAP with dual PH domains 1
ADTRP androgen-dependent TFPI-regulating protein
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALS2CL ALS2 C-terminal like
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
BCORL1 BCL6 corepressor-like 1
BIRC7 baculoviral IAP repeat containing 7
C19ORF73 chromosome 19 open reading frame 73
C1ORF159 chromosome 1 open reading frame 159
C22ORF29 chromosome 22 open reading frame 29
C2ORF27A chromosome 2 open reading frame 27A
C3 complement component 3
CCDC130 coiled-coil domain containing 130
CCDC132 coiled-coil domain containing 132
CCDC64 coiled-coil domain containing 64
CCNK cyclin K
CD3D CD3d molecule, delta (CD3-TCR complex)
CGA glycoprotein hormones, alpha polypeptide
CORO7 coronin 7
CRIP1 cysteine-rich protein 1 (intestinal)
CRLF1 cytokine receptor-like factor 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DSCAM Down syndrome cell adhesion molecule
ERO1L ERO1-like (S. cerevisiae)
EXD3 exonuclease 3'-5' domain containing 3
FBXL6 F-box and leucine-rich repeat protein 6
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FMOD fibromodulin
FSD1 fibronectin type III and SPRY domain containing 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
HIST1H3E histone cluster 1, H3e
HIST1H3G histone cluster 1, H3g
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IDI2-AS1 IDI2 antisense RNA 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL12RB1 interleukin 12 receptor, beta 1
IL15RA interleukin 15 receptor, alpha
IQSEC2 IQ motif and Sec7 domain 2
ITM2C integral membrane protein 2C
ITPKB inositol-trisphosphate 3-kinase B
JMJD4 jumonji domain containing 4
KCTD17 potassium channel tetramerization domain containing 17
KRT15 keratin 15, type I
KRT16 keratin 16, type I
LRP5L low density lipoprotein receptor-related protein 5-like
LZTS3 leucine zipper, putative tumor suppressor family member 3
MUC3A mucin 3A, cell surface associated
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
ONECUT2 one cut homeobox 2
PCDHGA8 protocadherin gamma subfamily A, 8
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G3 phospholipase A2, group III
PLCD1 phospholipase C, delta 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNA3 plexin A3
POLH polymerase (DNA directed), eta
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RND1 Rho family GTPase 1
SCARA3 scavenger receptor class A, member 3
SCN1B sodium channel, voltage gated, type I beta subunit
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIRT4 sirtuin 4
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNTA1 syntrophin, alpha 1
SOAT2 sterol O-acyltransferase 2
STARD3 StAR-related lipid transfer (START) domain containing 3
SYNC syncoilin, intermediate filament protein
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK1 TAO kinase 1
TBC1D2 TBC1 domain family, member 2
TCP10 t-complex 10
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRABD TraB domain containing
TSC22D4 TSC22 domain family, member 4
TTBK2 tau tubulin kinase 2
USP27X ubiquitin specific peptidase 27, X-linked
USP6NL USP6 N-terminal like
VPS9D1 VPS9 domain containing 1
XYLT2 xylosyltransferase II
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZIC3 Zic family member 3
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF134 zinc finger protein 134
ZNF816 zinc finger protein 816