levcycloserine-3789 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the levcycloserine-3789 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
AGFG2 ArfGAP with FG repeats 2
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATN1 atrophin 1
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BLVRA biliverdin reductase A
C10ORF12 chromosome 10 open reading frame 12
C17ORF59 chromosome 17 open reading frame 59
C22ORF46 chromosome 22 open reading frame 46
C8ORF44 chromosome 8 open reading frame 44
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CDC14B cell division cycle 14B
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
COX5B cytochrome c oxidase subunit Vb
CSDC2 cold shock domain containing C2, RNA binding
CT62 cancer/testis antigen 62
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
CYTH4 cytohesin 4
DGCR6L DiGeorge syndrome critical region gene 6-like
DHRS7 dehydrogenase/reductase (SDR family) member 7
DNAAF1 dynein, axonemal, assembly factor 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
E2F5 E2F transcription factor 5, p130-binding
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EFR3B EFR3 homolog B (S. cerevisiae)
EIF5B eukaryotic translation initiation factor 5B
FGF7 fibroblast growth factor 7
FLOT1 flotillin 1
FSCN2 fascin actin-bundling protein 2, retinal
FZD10 frizzled class receptor 10
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GFRA1 GDNF family receptor alpha 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPATCH4 G patch domain containing 4
GRM2 glutamate receptor, metabotropic 2
GRM7 glutamate receptor, metabotropic 7
GRSF1 G-rich RNA sequence binding factor 1
GUK1 guanylate kinase 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HEXA hexosaminidase A (alpha polypeptide)
HMGA1 high mobility group AT-hook 1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ING2 inhibitor of growth family, member 2
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KRT7 keratin 7, type II
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LINC00115 long intergenic non-protein coding RNA 115
LINC00652 long intergenic non-protein coding RNA 652
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LTBP4 latent transforming growth factor beta binding protein 4
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MX2 MX dynamin-like GTPase 2
NCKAP1 NCK-associated protein 1
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
NUDC nudC nuclear distribution protein
OAZ3 ornithine decarboxylase antizyme 3
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAWR PRKC, apoptosis, WT1, regulator
PCSK6 proprotein convertase subtilisin/kexin type 6
PGK1 phosphoglycerate kinase 1
PMCH pro-melanin-concentrating hormone
POU5F1B POU class 5 homeobox 1B
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRRC2C proline-rich coiled-coil 2C
PTCRA pre T-cell antigen receptor alpha
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PVRIG poliovirus receptor related immunoglobulin domain containing
PXN paxillin
RAB2A RAB2A, member RAS oncogene family
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RPAIN RPA interacting protein
RPL14 ribosomal protein L14
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPLP2 ribosomal protein, large, P2
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SAP30 Sin3A-associated protein, 30kDa
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SSX1 synovial sarcoma, X breakpoint 1
TMOD1 tropomodulin 1
TXN thioredoxin
UBE2I ubiquitin-conjugating enzyme E2I
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VDAC3 voltage-dependent anion channel 3
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WAPAL wings apart-like homolog (Drosophila)
WSB1 WD repeat and SOCS box containing 1
YY1 YY1 transcription factor

decreased expression

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ADGRL2 adhesion G protein-coupled receptor L2
ANKRD36 ankyrin repeat domain 36
ANXA10 annexin A10
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARSB arylsulfatase B
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C11ORF63 chromosome 11 open reading frame 63
C14ORF93 chromosome 14 open reading frame 93
C17ORF70 chromosome 17 open reading frame 70
C1R complement component 1, r subcomponent
CBS cystathionine-beta-synthase
CCNT1 cyclin T1
CDH7 cadherin 7, type 2
CFAP45 cilia and flagella associated protein 45
CHM choroideremia (Rab escort protein 1)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CINP cyclin-dependent kinase 2 interacting protein
CIR1 corepressor interacting with RBPJ, 1
COBL cordon-bleu WH2 repeat protein
CPED1 cadherin-like and PC-esterase domain containing 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNAL4 dynein, axonemal, light chain 4
DUSP9 dual specificity phosphatase 9
EDAR ectodysplasin A receptor
EGLN3 egl-9 family hypoxia-inducible factor 3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM118A family with sequence similarity 118, member A
FANCC Fanconi anemia, complementation group C
GJC1 gap junction protein, gamma 1, 45kDa
GPR19 G protein-coupled receptor 19
GRTP1 growth hormone regulated TBC protein 1
GSTCD glutathione S-transferase, C-terminal domain containing
HHAT hedgehog acyltransferase
HIST1H1D histone cluster 1, H1d
HIST1H3C histone cluster 1, H3c
HIST1H3G histone cluster 1, H3g
HIST1H4D histone cluster 1, H4d
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
KDM7A lysine (K)-specific demethylase 7A
KDM8 lysine (K)-specific demethylase 8
KIAA0754 KIAA0754
KLHL36 kelch-like family member 36
KRT4 keratin 4, type II
LINC00597 long intergenic non-protein coding RNA 597
LMCD1 LIM and cysteine-rich domains 1
LOC257152 uncharacterized LOC257152
LPAR3 lysophosphatidic acid receptor 3
LRRK1 leucine-rich repeat kinase 1
MFSD6 major facilitator superfamily domain containing 6
MMP3 matrix metallopeptidase 3
MTMR12 myotubularin related protein 12
NABP1 nucleic acid binding protein 1
NEK11 NIMA-related kinase 11
NKX3-2 NK3 homeobox 2
ODF2 outer dense fiber of sperm tails 2
PAQR5 progestin and adipoQ receptor family member V
PGPEP1 pyroglutamyl-peptidase I
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRB3 proline-rich protein BstNI subfamily 3
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
QPCTL glutaminyl-peptide cyclotransferase-like
RBMS3 RNA binding motif, single stranded interacting protein 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS17P5 ribosomal protein S17 pseudogene 5
SAYSD1 SAYSVFN motif domain containing 1
SCIN scinderin
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SETD1B SET domain containing 1B
SETD8 SET domain containing (lysine methyltransferase) 8
SLC25A40 solute carrier family 25, member 40
SLC46A3 solute carrier family 46, member 3
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLITRK5 SLIT and NTRK-like family, member 5
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STK16 serine/threonine kinase 16
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TET3 tet methylcytosine dioxygenase 3
TMEM19 transmembrane protein 19
VGF VGF nerve growth factor inducible
ZBTB33 zinc finger and BTB domain containing 33
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF219 zinc finger protein 219
ZNF286A zinc finger protein 286A
ZNF324 zinc finger protein 324
ZNF334 zinc finger protein 334
ZNF385D zinc finger protein 385D
ZNF76 zinc finger protein 76