levamisole-2094 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the levamisole-2094 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AIRE autoimmune regulator
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANKMY1 ankyrin repeat and MYND domain containing 1
ARPIN actin-related protein 2/3 complex inhibitor
AXIN1 axin 1
BEGAIN brain-enriched guanylate kinase-associated
C14ORF105 chromosome 14 open reading frame 105
CA9 carbonic anhydrase IX
CACYBP calcyclin binding protein
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCL20 chemokine (C-C motif) ligand 20
CEL carboxyl ester lipase
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNTLN centlein, centrosomal protein
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DSCR4 Down syndrome critical region 4
ELSPBP1 epididymal sperm binding protein 1
EPS8L1 EPS8-like 1
EPS8L3 EPS8-like 3
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF1 fibroblast growth factor 1 (acidic)
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXA2 forkhead box A2
FOXO4 forkhead box O4
FURIN furin (paired basic amino acid cleaving enzyme)
GAL3ST4 galactose-3-O-sulfotransferase 4
GLP1R glucagon-like peptide 1 receptor
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSK3A glycogen synthase kinase 3 alpha
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXB5 homeobox B5
HR hair growth associated
ICAM1 intercellular adhesion molecule 1
KLF3 Kruppel-like factor 3 (basic)
LINC00115 long intergenic non-protein coding RNA 115
LPPR4 lipid phosphate phosphatase-related protein type 4
LZTS1 leucine zipper, putative tumor suppressor 1
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
METTL5 methyltransferase like 5
MFAP3L microfibrillar-associated protein 3-like
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIA2 melanoma inhibitory activity 2
MINK1 misshapen-like kinase 1
MTCP1 mature T-cell proliferation 1
MYCNOS MYCN opposite strand
MYL5 myosin, light chain 5, regulatory
MYO7A myosin VIIA
MYOZ1 myozenin 1
MYOZ3 myozenin 3
NCKIPSD NCK interacting protein with SH3 domain
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEK3 NIMA-related kinase 3
NR2F2 nuclear receptor subfamily 2, group F, member 2
NT5M 5',3'-nucleotidase, mitochondrial
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFA platelet-derived growth factor alpha polypeptide
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PHLDB1 pleckstrin homology-like domain, family B, member 1
PKNOX2 PBX/knotted 1 homeobox 2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POU3F1 POU class 3 homeobox 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRF1 perforin 1 (pore forming protein)
PTGIS prostaglandin I2 (prostacyclin) synthase
RABGAP1 RAB GTPase activating protein 1
RARA retinoic acid receptor, alpha
REST RE1-silencing transcription factor
RNF122 ring finger protein 122
RPS4Y1 ribosomal protein S4, Y-linked 1
RRAD Ras-related associated with diabetes
RTEL1 regulator of telomere elongation helicase 1
S1PR1 sphingosine-1-phosphate receptor 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEC14L5 SEC14-like 5 (S. cerevisiae)
SENP6 SUMO1/sentrin specific peptidase 6
SFTPB surfactant protein B
SH2B1 SH2B adaptor protein 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIKE1 suppressor of IKBKE 1
SLA Src-like-adaptor
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SOX15 SRY (sex determining region Y)-box 15
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TRIM29 tripartite motif containing 29
TRPC1 transient receptor potential cation channel, subfamily C, member 1
WIPI2 WD repeat domain, phosphoinositide interacting 2
XDH xanthine dehydrogenase
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFHX3 zinc finger homeobox 3
ZNF37BP zinc finger protein 37B, pseudogene
ZNF768 zinc finger protein 768

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACAD10 acyl-CoA dehydrogenase family, member 10
ACOX2 acyl-CoA oxidase 2, branched chain
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ARRB2 arrestin, beta 2
ASB13 ankyrin repeat and SOCS box containing 13
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCL2L2 BCL2-like 2
BOLA1 bolA family member 1
BTBD2 BTB (POZ) domain containing 2
C11ORF80 chromosome 11 open reading frame 80
C16ORF62 chromosome 16 open reading frame 62
CAPN5 calpain 5
CCDC25 coiled-coil domain containing 25
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CORO1A coronin, actin binding protein, 1A
DBR1 debranching RNA lariats 1
EGLN2 egl-9 family hypoxia-inducible factor 2
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FBXL7 F-box and leucine-rich repeat protein 7
FGGY FGGY carbohydrate kinase domain containing
FLRT3 fibronectin leucine rich transmembrane protein 3
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALK1 galactokinase 1
GLI3 GLI family zinc finger 3
GLT8D2 glycosyltransferase 8 domain containing 2
GRWD1 glutamate-rich WD repeat containing 1
HINFP histone H4 transcription factor
HIRA histone cell cycle regulator
HP1BP3 heterochromatin protein 1, binding protein 3
KIAA0513 KIAA0513
KIF3A kinesin family member 3A
KRBOX4 KRAB box domain containing 4
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRRC42 leucine rich repeat containing 42
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAST3 microtubule associated serine/threonine kinase 3
MATN3 matrilin 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MTG1 mitochondrial ribosome-associated GTPase 1
MTMR6 myotubularin related protein 6
MXD3 MAX dimerization protein 3
MYL9 myosin, light chain 9, regulatory
NBEAL2 neurobeachin-like 2
NPR3 natriuretic peptide receptor 3
OLFML3 olfactomedin-like 3
ORAI3 ORAI calcium release-activated calcium modulator 3
OSMR oncostatin M receptor
P3H2 prolyl 3-hydroxylase 2
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae)
PARP16 poly (ADP-ribose) polymerase family, member 16
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAC8 placenta-specific 8
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPP6R3 protein phosphatase 6, regulatory subunit 3
PYCARD PYD and CARD domain containing
RAB3A RAB3A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RECQL4 RecQ protein-like 4
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPUSD2 RNA pseudouridylate synthase domain containing 2
RUSC2 RUN and SH3 domain containing 2
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A40 solute carrier family 25, member 40
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SMG9 SMG9 nonsense mediated mRNA decay factor
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STARD13 StAR-related lipid transfer (START) domain containing 13
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TLN1 talin 1
TMEM40 transmembrane protein 40
TMEM53 transmembrane protein 53
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSC1 tuberous sclerosis 1
TWISTNB TWIST neighbor
TXLNG taxilin gamma
UBQLN4 ubiquilin 4
UBXN6 UBX domain protein 6
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
USP6NL USP6 N-terminal like
XAB2 XPA binding protein 2
ZNF107 zinc finger protein 107
ZNF112 zinc finger protein 112
ZNF189 zinc finger protein 189
ZNF254 zinc finger protein 254
ZNF280D zinc finger protein 280D
ZNF551 zinc finger protein 551
ZNF574 zinc finger protein 574
ZNF84 zinc finger protein 84