leukemia, lymphocytic, chronic, b-cell Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
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Genes

202 genes associated with the disease leukemia, lymphocytic, chronic, b-cell in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACOXL acyl-CoA oxidase-like
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
APAF1 apoptotic peptidase activating factor 1
APOE apolipoprotein E
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
AURKB aurora kinase B
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BID BH3 interacting domain death agonist
BIRC5 baculoviral IAP repeat containing 5
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CAPN2 calpain 2, (m/II) large subunit
CAPN3 calpain 3, (p94)
CAPN9 calpain 9
CARD8 caspase recruitment domain family, member 8
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL27 chemokine (C-C motif) ligand 27
CCND1 cyclin D1
CCNH cyclin H
CCR7 chemokine (C-C motif) receptor 7
CCR8 chemokine (C-C motif) receptor 8
CD28 CD28 molecule
CD38 CD38 molecule
CDC25C cell division cycle 25C
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CDK6 cyclin-dependent kinase 6
CENPF centromere protein F, 350/400kDa
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPT1B carnitine palmitoyltransferase 1B (muscle)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCLRE1C DNA cross-link repair 1C
DISC1 disrupted in schizophrenia 1
E2F2 E2F transcription factor 2
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ENO2 enolase 2 (gamma, neuronal)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
ERCC6 excision repair cross-complementation group 6
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
EXO1 exonuclease 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FADD Fas (TNFRSF6)-associated via death domain
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF4 fibroblast growth factor 4
GMNN geminin, DNA replication inhibitor
GNAS GNAS complex locus
GSTA2 glutathione S-transferase alpha 2
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GSTZ1 glutathione S-transferase zeta 1
HFE hemochromatosis
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IFNG interferon, gamma
IGF2R insulin-like growth factor 2 receptor
IGH immunoglobulin heavy locus
IL10 interleukin 10
IL12A interleukin 12A
IL12RB1 interleukin 12 receptor, beta 1
IL13 interleukin 13
IL16 interleukin 16
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
IL1RL2 interleukin 1 receptor-like 2
IL1RN interleukin 1 receptor antagonist
IL3 interleukin 3
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5RA interleukin 5 receptor, alpha
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IRAK4 interleukin-1 receptor-associated kinase 4
IRF4 interferon regulatory factor 4
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITGB4 integrin, beta 4
LIG4 ligase IV, DNA, ATP-dependent
LTA lymphotoxin alpha
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
N4BP1 NEDD4 binding protein 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBN nibrin
NLRP1 NLR family, pyrin domain containing 1
NLRP11 NLR family, pyrin domain containing 11
NLRP13 NLR family, pyrin domain containing 13
NLRP14 NLR family, pyrin domain containing 14
NLRP2 NLR family, pyrin domain containing 2
NLRP4 NLR family, pyrin domain containing 4
NLRP5 NLR family, pyrin domain containing 5
NLRP8 NLR family, pyrin domain containing 8
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NQO1 NAD(P)H dehydrogenase, quinone 1
OPRM1 opioid receptor, mu 1
ORC3 origin recognition complex, subunit 3
ORC4 origin recognition complex, subunit 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PARP1 poly (ADP-ribose) polymerase 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PML promyelocytic leukemia
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLI polymerase (DNA directed) iota
POLL polymerase (DNA directed), lambda
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRKD2 protein kinase D2
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTCH1 patched 1
RAD1 RAD1 checkpoint DNA exonuclease
RAD21 RAD21 homolog (S. pombe)
RAD23B RAD23 homolog B (S. cerevisiae)
RAD51 RAD51 recombinase
RAG1 recombination activating gene 1
RAP1GAP RAP1 GTPase activating protein
RBL2 retinoblastoma-like 2
RCAN1 regulator of calcineurin 1
RCAN3 RCAN family member 3
REV1 REV1, polymerase (DNA directed)
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SOD2 superoxide dismutase 2, mitochondrial
SP110 SP110 nuclear body protein
SP140 SP140 nuclear body protein
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP73 tumor protein p73
TRAF3 TNF receptor-associated factor 3
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
XCL1 chemokine (C motif) ligand 1
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6