lesion Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

275 genes co-occuring with the biological term lesion in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AAMP angio-associated, migratory cell protein
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACE angiotensin I converting enzyme
ADAM8 ADAM metallopeptidase domain 8
ADIPOQ adiponectin, C1Q and collagen domain containing
AGTR1 angiotensin II receptor, type 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
ALMS1 Alstrom syndrome protein 1
ALOX5 arachidonate 5-lipoxygenase
ANGPT1 angiopoietin 1
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOE apolipoprotein E
AQP4 aquaporin 4
ARMS2 age-related maculopathy susceptibility 2
ARNT aryl hydrocarbon receptor nuclear translocator
ATXN2 ataxin 2
AVP arginine vasopressin
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BSG basigin (Ok blood group)
C9ORF72 chromosome 9 open reading frame 72
CA2 carbonic anhydrase II
CADM1 cell adhesion molecule 1
CANT1 calcium activated nucleotidase 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CCR2 chemokine (C-C motif) receptor 2
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD80 CD80 molecule
CD86 CD86 molecule
CD9 CD9 molecule
CD99 CD99 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CETP cholesteryl ester transfer protein, plasma
CFH complement factor H
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIT1 chitinase 1 (chitotriosidase)
CLC Charcot-Leyden crystal galectin
CNR1 cannabinoid receptor 1 (brain)
COL18A1 collagen, type XVIII, alpha 1
COL4A5 collagen, type IV, alpha 5
CORT cortistatin
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CUL1 cullin 1
CUL4A cullin 4A
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR5 chemokine (C-X-C motif) receptor 5
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
DAPK1 death-associated protein kinase 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPP4 dipeptidyl-peptidase 4
EBP emopamil binding protein (sterol isomerase)
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
ERCC6 excision repair cross-complementation group 6
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F13A1 coagulation factor XIII, A1 polypeptide
FABP4 fatty acid binding protein 4, adipocyte
FANCD2 Fanconi anemia, complementation group D2
FANCM Fanconi anemia, complementation group M
FBXO11 F-box protein 11
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FHIT fragile histidine triad
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXP3 forkhead box P3
FXYD1 FXYD domain containing ion transport regulator 1
GAP43 growth associated protein 43
GFAP glial fibrillary acidic protein
GGT1 gamma-glutamyltransferase 1
GLRX5 glutaredoxin 5
GNAS GNAS complex locus
GP6 glycoprotein VI (platelet)
GPC3 glypican 3
GSTT1 glutathione S-transferase theta 1
HBEGF heparin-binding EGF-like growth factor
HDAC1 histone deacetylase 1
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA4 heat shock 70kDa protein 4
ICAM1 intercellular adhesion molecule 1
IFNK interferon, kappa
IFNL1 interferon, lambda 1
IFNLR1 interferon, lambda receptor 1
IL10 interleukin 10
IL17A interleukin 17A
IL18 interleukin 18
IL4 interleukin 4
IL6 interleukin 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPKC inositol-trisphosphate 3-kinase C
JAK2 Janus kinase 2
JUN jun proto-oncogene
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRIT1 KRIT1, ankyrin repeat containing
KRT16 keratin 16, type I
LCN2 lipocalin 2
LEP leptin
LGALS3 lectin, galactoside-binding, soluble, 3
LHX3 LIM homeobox 3
MAL mal, T-cell differentiation protein
MAOA monoamine oxidase A
MAPT microtubule-associated protein tau
MCM4 minichromosome maintenance complex component 4
MCM7 minichromosome maintenance complex component 7
MGMT O-6-methylguanine-DNA methyltransferase
MIR21 microRNA 21
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPG N-methylpurine-DNA glycosylase
MTA1 metastasis associated 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC16 mucin 16, cell surface associated
MX1 MX dynamin-like GTPase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCR1 natural cytotoxicity triggering receptor 1
NF1 neurofibromin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NMRAL1 NmrA-like family domain containing 1
NOG noggin
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH2 notch 2
NPPB natriuretic peptide B
NPY neuropeptide Y
NR1D1 nuclear receptor subfamily 1, group D, member 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTF3 neurotrophin 3
NTN1 netrin 1
OGG1 8-oxoguanine DNA glycosylase
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
ORAI1 ORAI calcium release-activated calcium modulator 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP1 poly (ADP-ribose) polymerase 1
PAX2 paired box 2
PCDH10 protocadherin 10
PCNA proliferating cell nuclear antigen
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDPN podoplanin
PF4 platelet factor 4
PLA2G10 phospholipase A2, group X
PLA2G5 phospholipase A2, group V
PLAU plasminogen activator, urokinase
PLIN2 perilipin 2
POLB polymerase (DNA directed), beta
POLH polymerase (DNA directed), eta
POLI polymerase (DNA directed) iota
POLK polymerase (DNA directed) kappa
POLL polymerase (DNA directed), lambda
POLM polymerase (DNA directed), mu
POLQ polymerase (DNA directed), theta
PON1 paraoxonase 1
PON3 paraoxonase 3
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PRDX1 peroxiredoxin 1
PRKCH protein kinase C, eta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RARB retinoic acid receptor, beta
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RETN resistin
REV1 REV1, polymerase (DNA directed)
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RHEB Ras homolog enriched in brain
RPA1 replication protein A1, 70kDa
S100A12 S100 calcium binding protein A12
S100B S100 calcium binding protein B
SCN3A sodium channel, voltage gated, type III alpha subunit
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SH3BP2 SH3-domain binding protein 2
SHH sonic hedgehog
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLIT2 slit homolog 2 (Drosophila)
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOS1 son of sevenless homolog 1 (Drosophila)
SPRTN SprT-like N-terminal domain
SRA1 steroid receptor RNA activator 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TBXAS1 thromboxane A synthase 1 (platelet)
TDP1 tyrosyl-DNA phosphodiesterase 1
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TF transferrin
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMPRSS2 transmembrane protease, serine 2
TNC tenascin C
TNF tumor necrosis factor
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TSC2 tuberous sclerosis 2
TWIST1 twist family bHLH transcription factor 1
TWIST2 twist family bHLH transcription factor 2
UBC ubiquitin C
USF1 upstream transcription factor 1
VCAN versican
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VSIG4 V-set and immunoglobulin domain containing 4
VTCN1 V-set domain containing T cell activation inhibitor 1
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1