laudanosine-7270 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the laudanosine-7270 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADCY6 adenylate cyclase 6
AP1M2 adaptor-related protein complex 1, mu 2 subunit
ARHGAP28 Rho GTPase activating protein 28
ARRB2 arrestin, beta 2
AVL9 AVL9 homolog (S. cerevisiase)
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL6 B-cell CLL/lymphoma 6
BIN1 bridging integrator 1
BRD4 bromodomain containing 4
BTN3A1 butyrophilin, subfamily 3, member A1
CCDC85C coiled-coil domain containing 85C
CNTNAP2 contactin associated protein-like 2
COL3A1 collagen, type III, alpha 1
CSPP1 centrosome and spindle pole associated protein 1
CST6 cystatin E/M
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGF epidermal growth factor
FA2H fatty acid 2-hydroxylase
FGF13 fibroblast growth factor 13
FKBP8 FK506 binding protein 8, 38kDa
FXR2 fragile X mental retardation, autosomal homolog 2
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLG1 golgi glycoprotein 1
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GPR107 G protein-coupled receptor 107
HLF hepatic leukemia factor
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOMER2 homer scaffolding protein 2
HPS4 Hermansky-Pudlak syndrome 4
IGFBP5 insulin-like growth factor binding protein 5
IL24 interleukin 24
ING1 inhibitor of growth family, member 1
IPO8 importin 8
IRF6 interferon regulatory factor 6
KDM7A lysine (K)-specific demethylase 7A
KIF5C kinesin family member 5C
KIFC1 kinesin family member C1
LIG4 ligase IV, DNA, ATP-dependent
LOC644450 uncharacterized LOC644450
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MBD3 methyl-CpG binding domain protein 3
MBTD1 mbt domain containing 1
MIIP migration and invasion inhibitory protein
NCKIPSD NCK interacting protein with SH3 domain
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NPTXR neuronal pentraxin receptor
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAX9 paired box 9
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PER1 period circadian clock 1
PGAP1 post-GPI attachment to proteins 1
PHTF2 putative homeodomain transcription factor 2
PLAC1 placenta-specific 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLM polymerase (DNA directed), mu
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PVT1 Pvt1 oncogene (non-protein coding)
RGS10 regulator of G-protein signaling 10
RREB1 ras responsive element binding protein 1
SCAMP1 secretory carrier membrane protein 1
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC38A7 solute carrier family 38, member 7
SLC46A3 solute carrier family 46, member 3
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMG7 SMG7 nonsense mediated mRNA decay factor
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SOX13 SRY (sex determining region Y)-box 13
TM4SF5 transmembrane 4 L six family member 5
TMEM242 transmembrane protein 242
TNC tenascin C
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM14 tripartite motif containing 14
UBXN1 UBX domain protein 1
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
USP19 ubiquitin specific peptidase 19
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF200 zinc finger protein 200
ZNF224 zinc finger protein 224
ZNF274 zinc finger protein 274
ZNF358 zinc finger protein 358
ZNF408 zinc finger protein 408
ZNF500 zinc finger protein 500
ZNF609 zinc finger protein 609
ZNF749 zinc finger protein 749
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
AEN apoptosis enhancing nuclease
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AKIP1 A kinase (PRKA) interacting protein 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AZI2 5-azacytidine induced 2
BAHD1 bromo adjacent homology domain containing 1
BIK BCL2-interacting killer (apoptosis-inducing)
C16ORF59 chromosome 16 open reading frame 59
CADPS2 Ca++-dependent secretion activator 2
CCNO cyclin O
CCNT1 cyclin T1
CEP170B centrosomal protein 170B
CEP72 centrosomal protein 72kDa
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIR1 corepressor interacting with RBPJ, 1
CLDN15 claudin 15
CLDN3 claudin 3
CTSF cathepsin F
CUL9 cullin 9
CXORF56 chromosome X open reading frame 56
DBF4B DBF4 zinc finger B
DSE dermatan sulfate epimerase
DSPP dentin sialophosphoprotein
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EAF2 ELL associated factor 2
EPHA4 EPH receptor A4
ERCC2 excision repair cross-complementation group 2
FAM169A family with sequence similarity 169, member A
FAM86C1 family with sequence similarity 86, member C1
FICD FIC domain containing
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH1 G patch domain containing 1
GRPR gastrin-releasing peptide receptor
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HHLA3 HERV-H LTR-associating 3
HIST1H3G histone cluster 1, H3g
HLX H2.0-like homeobox
HOXC10 homeobox C10
HPS6 Hermansky-Pudlak syndrome 6
HPSE heparanase
INF2 inverted formin, FH2 and WH2 domain containing
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA0556 KIAA0556
KLK5 kallikrein-related peptidase 5
KRI1 KRI1 homolog (S. cerevisiae)
LMBR1L limb development membrane protein 1-like
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MED15 mediator complex subunit 15
MN1 meningioma (disrupted in balanced translocation) 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MST1R macrophage stimulating 1 receptor
MUC3B mucin 3B, cell surface associated
MVP major vault protein
NAG18 NAG18 mRNA
NMB neuromedin B
NUBP2 nucleotide binding protein 2
OSBP2 oxysterol binding protein 2
OSMR oncostatin M receptor
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRICKLE3 prickle homolog 3 (Drosophila)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF25 ring finger protein 25
SECTM1 secreted and transmembrane 1
SH2D4A SH2 domain containing 4A
SLC12A8 solute carrier family 12, member 8
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNX24 sorting nexin 24
SUGCT succinyl-CoA:glutarate-CoA transferase
TBC1D12 TBC1 domain family, member 12
TESK1 testis-specific kinase 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM183A transmembrane protein 183A
TOLLIP toll interacting protein
TPRA1 transmembrane protein, adipocyte asscociated 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTBK2 tau tubulin kinase 2
USP27X ubiquitin specific peptidase 27, X-linked
USP32 ubiquitin specific peptidase 32
VWA1 von Willebrand factor A domain containing 1
WDR60 WD repeat domain 60
XAB2 XPA binding protein 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF177 zinc finger protein 177
ZNF227 zinc finger protein 227
ZNF273 zinc finger protein 273
ZNF862 zinc finger protein 862