laudanosine-7030 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the laudanosine-7030 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
AXIN1 axin 1
C8A complement component 8, alpha polypeptide
CA4 carbonic anhydrase IV
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX4 chromobox homolog 4
CD302 CD302 molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CLTA clathrin, light chain A
COMT catechol-O-methyltransferase
CRY2 cryptochrome circadian clock 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DOK4 docking protein 4
DRD2 dopamine receptor D2
EDA ectodysplasin A
EDNRA endothelin receptor type A
EFNB3 ephrin-B3
ELOVL5 ELOVL fatty acid elongase 5
F2R coagulation factor II (thrombin) receptor
FAM188A family with sequence similarity 188, member A
FGFR1 fibroblast growth factor receptor 1
FHL1 four and a half LIM domains 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GGPS1 geranylgeranyl diphosphate synthase 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPER1 G protein-coupled estrogen receptor 1
GPX2 glutathione peroxidase 2
GRB10 growth factor receptor-bound protein 10
GSAP gamma-secretase activating protein
GYG2 glycogenin 2
HIST1H2AK histone cluster 1, H2ak
HPS1 Hermansky-Pudlak syndrome 1
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KLK5 kallikrein-related peptidase 5
LIG3 ligase III, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
LPPR2 lipid phosphate phosphatase-related protein type 2
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LYRM9 LYR motif containing 9
LZTR1 leucine-zipper-like transcription regulator 1
MAPK14 mitogen-activated protein kinase 14
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MIIP migration and invasion inhibitory protein
MLX MLX, MAX dimerization protein
N4BP2L2 NEDD4 binding protein 2-like 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NF1 neurofibromin 1
NLK nemo-like kinase
NTF3 neurotrophin 3
PCM1 pericentriolar material 1
PDE11A phosphodiesterase 11A
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF20 PHD finger protein 20
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RANBP1 RAN binding protein 1
RBM34 RNA binding motif protein 34
S100A13 S100 calcium binding protein A13
SELL selectin L
SENP6 SUMO1/sentrin specific peptidase 6
SETD1A SET domain containing 1A
SIK3 SIK family kinase 3
SLIT2 slit homolog 2 (Drosophila)
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SOX13 SRY (sex determining region Y)-box 13
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPON1 spondin 1, extracellular matrix protein
SPRED2 sprouty-related, EVH1 domain containing 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STK17B serine/threonine kinase 17b
SYP synaptophysin
TCF3 transcription factor 3
TMEM183A transmembrane protein 183A
TMPRSS2 transmembrane protease, serine 2
TP53I11 tumor protein p53 inducible protein 11
TRAF3IP2 TRAF3 interacting protein 2
TRAK1 trafficking protein, kinesin binding 1
TUBA3C tubulin, alpha 3c
UNC119 unc-119 homolog (C. elegans)
USP20 ubiquitin specific peptidase 20
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR25 WD repeat domain 25
ZBTB1 zinc finger and BTB domain containing 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF324 zinc finger protein 324
ZNF770 zinc finger protein 770
ZNF79 zinc finger protein 79
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACSS3 acyl-CoA synthetase short-chain family member 3
ACVR2B activin A receptor, type IIB
ARHGAP10 Rho GTPase activating protein 10
ATAD5 ATPase family, AAA domain containing 5
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCOR BCL6 corepressor
C10ORF88 chromosome 10 open reading frame 88
C19ORF40 chromosome 19 open reading frame 40
C3ORF52 chromosome 3 open reading frame 52
C5ORF45 chromosome 5 open reading frame 45
CAPN5 calpain 5
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN15 claudin 15
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRABP1 cellular retinoic acid binding protein 1
CUEDC1 CUE domain containing 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
EFNA3 ephrin-A3
ELSPBP1 epididymal sperm binding protein 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FANCE Fanconi anemia, complementation group E
GAMT guanidinoacetate N-methyltransferase
GAS8 growth arrest-specific 8
GPATCH1 G patch domain containing 1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFT140 intraflagellar transport 140
IGFBP6 insulin-like growth factor binding protein 6
IL15RA interleukin 15 receptor, alpha
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF9 interferon regulatory factor 9
KIZ kizuna centrosomal protein
KLF3 Kruppel-like factor 3 (basic)
KLHL26 kelch-like family member 26
KRT13 keratin 13, type I
LRP3 low density lipoprotein receptor-related protein 3
MAMLD1 mastermind-like domain containing 1
MAP9 microtubule-associated protein 9
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBTD1 mbt domain containing 1
METTL2B methyltransferase like 2B
MITF microphthalmia-associated transcription factor
MOCS3 molybdenum cofactor synthesis 3
MT1H metallothionein 1H
MTA2 metastasis associated 1 family, member 2
MXD3 MAX dimerization protein 3
MYL5 myosin, light chain 5, regulatory
NECAP2 NECAP endocytosis associated 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
NUP62CL nucleoporin 62kDa C-terminal like
PARP12 poly (ADP-ribose) polymerase family, member 12
PGP phosphoglycolate phosphatase
POLL polymerase (DNA directed), lambda
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTDSS2 phosphatidylserine synthase 2
RAD54L RAD54-like (S. cerevisiae)
RASAL1 RAS protein activator like 1 (GAP1 like)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RIN2 Ras and Rab interactor 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RWDD3 RWD domain containing 3
SCAP SREBF chaperone
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SFMBT1 Scm-like with four mbt domains 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SKA1 spindle and kinetochore associated complex subunit 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC16A6 solute carrier family 16, member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC46A3 solute carrier family 46, member 3
SNAI2 snail family zinc finger 2
STBD1 starch binding domain 1
THBS3 thrombospondin 3
TMEM115 transmembrane protein 115
TMEM212 transmembrane protein 212
TMEM62 transmembrane protein 62
TPST2 tyrosylprotein sulfotransferase 2
TRIM5 tripartite motif containing 5
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTLL1 tubulin tyrosine ligase-like family member 1
UBXN8 UBX domain protein 8
WDR4 WD repeat domain 4
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H3 zinc finger CCCH-type containing 3
ZFP69B ZFP69 zinc finger protein B
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZMYM3 zinc finger, MYM-type 3
ZNF219 zinc finger protein 219
ZNF268 zinc finger protein 268
ZNF668 zinc finger protein 668