laudanosine-2890 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the laudanosine-2890 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACSL5 acyl-CoA synthetase long-chain family member 5
ANKMY1 ankyrin repeat and MYND domain containing 1
ARHGAP44 Rho GTPase activating protein 44
ARID4B AT rich interactive domain 4B (RBP1-like)
ASTN1 astrotactin 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C22ORF46 chromosome 22 open reading frame 46
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD4 CD4 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CDON cell adhesion associated, oncogene regulated
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CFLAR CASP8 and FADD-like apoptosis regulator
CHI3L2 chitinase 3-like 2
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
COL1A1 collagen, type I, alpha 1
COL6A2 collagen, type VI, alpha 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRTC1 CREB regulated transcription coactivator 1
CXCR2 chemokine (C-X-C motif) receptor 2
DFNB31 deafness, autosomal recessive 31
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
EMCN endomucin
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERP44 endoplasmic reticulum protein 44
FGL1 fibrinogen-like 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FRAS1 Fraser extracellular matrix complex subunit 1
GGTLC1 gamma-glutamyltransferase light chain 1
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRB10 growth factor receptor-bound protein 10
GSK3A glycogen synthase kinase 3 alpha
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HDAC11 histone deacetylase 11
HOXB5 homeobox B5
HRASLS2 HRAS-like suppressor 2
IGFBP5 insulin-like growth factor binding protein 5
INHBA inhibin, beta A
INO80D INO80 complex subunit D
ITPKA inositol-trisphosphate 3-kinase A
JAK3 Janus kinase 3
KDR kinase insert domain receptor
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLF12 Kruppel-like factor 12
LMNA lamin A/C
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAGEB4 melanoma antigen family B4
MED31 mediator complex subunit 31
MEF2D myocyte enhancer factor 2D
MUC13 mucin 13, cell surface associated
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal
N4BP3 NEDD4 binding protein 3
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NPHP1 nephronophthisis 1 (juvenile)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTF3 neurotrophin 3
NXPH4 neurexophilin 4
ONECUT2 one cut homeobox 2
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OSMR oncostatin M receptor
OTOR otoraplin
PDE4B phosphodiesterase 4B, cAMP-specific
PER2 period circadian clock 2
PGLYRP4 peptidoglycan recognition protein 4
PI15 peptidase inhibitor 15
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRDM14 PR domain containing 14
PROX1 prospero homeobox 1
PRSS53 protease, serine, 53
RBBP4 retinoblastoma binding protein 4
RGS2 regulator of G-protein signaling 2
RNFT1 ring finger protein, transmembrane 1
RPS3A ribosomal protein S3A
RPS4Y1 ribosomal protein S4, Y-linked 1
SCAND2P SCAN domain containing 2 pseudogene
SLC16A4 solute carrier family 16, member 4
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SLN sarcolipin
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPDEF SAM pointed domain containing ETS transcription factor
SPINK5 serine peptidase inhibitor, Kazal type 5
STEAP1 six transmembrane epithelial antigen of the prostate 1
TAPBP TAP binding protein (tapasin)
TBC1D2 TBC1 domain family, member 2
TGFB2 transforming growth factor, beta 2
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
UHRF1BP1L UHRF1 binding protein 1-like
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VAMP5 vesicle-associated membrane protein 5
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF652 zinc finger protein 652
ZNF804A zinc finger protein 804A

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ABLIM3 actin binding LIM protein family, member 3
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AES amino-terminal enhancer of split
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOLD1 apolipoprotein L domain containing 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASPHD1 aspartate beta-hydroxylase domain containing 1
BCORL1 BCL6 corepressor-like 1
BPHL biphenyl hydrolase-like (serine hydrolase)
C11ORF30 chromosome 11 open reading frame 30
C7ORF43 chromosome 7 open reading frame 43
CAMK1 calcium/calmodulin-dependent protein kinase I
CAPN5 calpain 5
CBX8 chromobox homolog 8
CCDC85C coiled-coil domain containing 85C
CFAP44 cilia and flagella associated protein 44
CHKB choline kinase beta
CISH cytokine inducible SH2-containing protein
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COL9A2 collagen, type IX, alpha 2
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DVL1 dishevelled segment polarity protein 1
ENO2 enolase 2 (gamma, neuronal)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERCC5 excision repair cross-complementation group 5
FAAH fatty acid amide hydrolase
FAM46C family with sequence similarity 46, member C
FBXL2 F-box and leucine-rich repeat protein 2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GEMIN8 gem (nuclear organelle) associated protein 8
GLCE glucuronic acid epimerase
GLS2 glutaminase 2 (liver, mitochondrial)
GSTA4 glutathione S-transferase alpha 4
GSTM2 glutathione S-transferase mu 2 (muscle)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IFI35 interferon-induced protein 35
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRAK4 interleukin-1 receptor-associated kinase 4
ITPKB inositol-trisphosphate 3-kinase B
KDM7A lysine (K)-specific demethylase 7A
KIAA0125 KIAA0125
KIZ kizuna centrosomal protein
KREMEN2 kringle containing transmembrane protein 2
LMNB1 lamin B1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LZTFL1 leucine zipper transcription factor-like 1
MAST3 microtubule associated serine/threonine kinase 3
MBNL3 muscleblind-like splicing regulator 3
METTL16 methyltransferase like 16
MFAP2 microfibrillar-associated protein 2
MNX1 motor neuron and pancreas homeobox 1
MPI mannose phosphate isomerase
MUTYH mutY homolog
NOL10 nucleolar protein 10
NOL6 nucleolar protein 6 (RNA-associated)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLFML3 olfactomedin-like 3
OSGIN1 oxidative stress induced growth inhibitor 1
PANK4 pantothenate kinase 4
PARG poly (ADP-ribose) glycohydrolase
PC pyruvate carboxylase
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PILRB paired immunoglobin-like type 2 receptor beta
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PODXL2 podocalyxin-like 2
POMT2 protein-O-mannosyltransferase 2
PRPH peripherin
RBM42 RNA binding motif protein 42
ROM1 retinal outer segment membrane protein 1
SCAMP5 secretory carrier membrane protein 5
SIX1 SIX homeobox 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPINK4 serine peptidase inhibitor, Kazal type 4
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX5 syntaxin 5
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TARP TCR gamma alternate reading frame protein
TCTA T-cell leukemia translocation altered
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM104 transmembrane protein 104
TMEM242 transmembrane protein 242
VGF VGF nerve growth factor inducible
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZMAT5 zinc finger, matrin-type 5
ZNF16 zinc finger protein 16
ZNF226 zinc finger protein 226
ZSCAN2 zinc finger and SCAN domain containing 2