laudanosine-1741 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the laudanosine-1741 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
ANGEL1 angel homolog 1 (Drosophila)
ARL4C ADP-ribosylation factor-like 4C
BCL2 B-cell CLL/lymphoma 2
BMP7 bone morphogenetic protein 7
C6 complement component 6
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAPN10 calpain 10
CCDC64 coiled-coil domain containing 64
CD180 CD180 molecule
CDC5L cell division cycle 5-like
CDCP1 CUB domain containing protein 1
CDK10 cyclin-dependent kinase 10
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CFAP74 cilia and flagella associated protein 74
CLEC4E C-type lectin domain family 4, member E
CNTFR ciliary neurotrophic factor receptor
CSH2 chorionic somatomammotropin hormone 2
CXCR3 chemokine (C-X-C motif) receptor 3
DGCR14 DiGeorge syndrome critical region gene 14
DPH2 DPH2 homolog (S. cerevisiae)
DST dystonin
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GJB4 gap junction protein, beta 4, 30.3kDa
GMPPB GDP-mannose pyrophosphorylase B
GRPR gastrin-releasing peptide receptor
GUCA1B guanylate cyclase activator 1B (retina)
HBB hemoglobin, beta
HUS1 HUS1 checkpoint homolog (S. pombe)
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGKV1D-13 immunoglobulin kappa variable 1D-13
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KLHL35 kelch-like family member 35
KRT2 keratin 2, type II
LDOC1 leucine zipper, down-regulated in cancer 1
LPAR3 lysophosphatidic acid receptor 3
LY6G5C lymphocyte antigen 6 complex, locus G5C
LY9 lymphocyte antigen 9
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCC mutated in colorectal cancers
MED14 mediator complex subunit 14
MED31 mediator complex subunit 31
MLH3 mutL homolog 3
MLPH melanophilin
MMP25 matrix metallopeptidase 25
MYOF myoferlin
NCAM1 neural cell adhesion molecule 1
NCOA3 nuclear receptor coactivator 3
NREP neuronal regeneration related protein
NXPH3 neurexophilin 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OPHN1 oligophrenin 1
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PAQR6 progestin and adipoQ receptor family member VI
PARD3 par-3 family cell polarity regulator
PBX2 pre-B-cell leukemia homeobox 2
PCDHB6 protocadherin beta 6
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKNOX2 PBX/knotted 1 homeobox 2
PLCB2 phospholipase C, beta 2
PMM2 phosphomannomutase 2
PSG9 pregnancy specific beta-1-glycoprotein 9
RANBP1 RAN binding protein 1
RBMS3 RNA binding motif, single stranded interacting protein 3
RNF17 ring finger protein 17
RNF170 ring finger protein 170
RORC RAR-related orphan receptor C
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPL7 ribosomal protein L7
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SH3BP2 SH3-domain binding protein 2
SLC22A14 solute carrier family 22, member 14
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SOCS6 suppressor of cytokine signaling 6
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
STAB2 stabilin 2
STARD13 StAR-related lipid transfer (START) domain containing 13
TBC1D13 TBC1 domain family, member 13
TFCP2L1 transcription factor CP2-like 1
TMCC2 transmembrane and coiled-coil domain family 2
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM35 transmembrane protein 35
TUB tubby bipartite transcription factor
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
USP29 ubiquitin specific peptidase 29
WFS1 Wolfram syndrome 1 (wolframin)
WNK1 WNK lysine deficient protein kinase 1
ZFHX4 zinc finger homeobox 4
ZNF460 zinc finger protein 460
ZNF611 zinc finger protein 611
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ABHD3 abhydrolase domain containing 3
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
ATPIF1 ATPase inhibitory factor 1
BANP BTG3 associated nuclear protein
BIRC2 baculoviral IAP repeat containing 2
C11ORF73 chromosome 11 open reading frame 73
CARKD carbohydrate kinase domain containing
CCND3 cyclin D3
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CFL1 cofilin 1 (non-muscle)
CHMP2A charged multivesicular body protein 2A
COPS7A COP9 signalosome subunit 7A
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
DDB1 damage-specific DNA binding protein 1, 127kDa
DDHD2 DDHD domain containing 2
DDT D-dopachrome tautomerase
DEGS1 delta(4)-desaturase, sphingolipid 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERH enhancer of rudimentary homolog (Drosophila)
EXOSC8 exosome component 8
EXOSC9 exosome component 9
FAM50A family with sequence similarity 50, member A
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GRAMD1B GRAM domain containing 1B
HCLS1 hematopoietic cell-specific Lyn substrate 1
HIST1H4C histone cluster 1, H4c
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
IER2 immediate early response 2
IMP4 IMP4, U3 small nucleolar ribonucleoprotein
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
IRAK1 interleukin-1 receptor-associated kinase 1
KIFC1 kinesin family member C1
LMO2 LIM domain only 2 (rhombotin-like 1)
LYRM2 LYR motif containing 2
MEX3C mex-3 RNA binding family member C
MKNK2 MAP kinase interacting serine/threonine kinase 2
MOAP1 modulator of apoptosis 1
MPST mercaptopyruvate sulfurtransferase
MRPL4 mitochondrial ribosomal protein L4
MRPL48 mitochondrial ribosomal protein L48
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NCL nucleolin
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NIP7 NIP7, nucleolar pre-rRNA processing protein
NIT2 nitrilase family, member 2
NUCB2 nucleobindin 2
NVL nuclear VCP-like
OLA1 Obg-like ATPase 1
ORM1 orosomucoid 1
PCID2 PCI domain containing 2
PLAG1 pleiomorphic adenoma gene 1
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRR13 proline rich 13
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
QARS glutaminyl-tRNA synthetase
RAD51AP1 RAD51 associated protein 1
RAP1A RAP1A, member of RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
REXO2 RNA exonuclease 2
RNF187 ring finger protein 187
RPL34 ribosomal protein L34
RPL36AL ribosomal protein L36a-like
RPS27L ribosomal protein S27-like
RTFDC1 replication termination factor 2 domain containing 1
SAR1B secretion associated, Ras related GTPase 1B
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEC61B Sec61 beta subunit
SETD3 SET domain containing 3
SMAP1 small ArfGAP 1
SOD1 superoxide dismutase 1, soluble
SRPRB signal recognition particle receptor, B subunit
TACC3 transforming, acidic coiled-coil containing protein 3
TARS threonyl-tRNA synthetase
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TCERG1 transcription elongation regulator 1
TMEM106B transmembrane protein 106B
TMEM251 transmembrane protein 251
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPST2 tyrosylprotein sulfotransferase 2
TRAPPC11 trafficking protein particle complex 11
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TSSC1 tumor suppressing subtransferable candidate 1
TTC1 tetratricopeptide repeat domain 1
TTF2 transcription termination factor, RNA polymerase II
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2M ubiquitin-conjugating enzyme E2M
UBL5 ubiquitin-like 5
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast)
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VAMP8 vesicle-associated membrane protein 8
WDR82 WD repeat domain 82
ZNF264 zinc finger protein 264