laryngeal squamous cell carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A laryngeal carcinoma that has_material_basis_in squamous cells. (Human Disease Ontology, DOID_2876)
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Genes

216 genes co-occuring with the disease laryngeal squamous cell carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TP53 tumor protein p53 1.43683
CAMSAP1 calmodulin regulated spectrin-associated protein 1 1.22735
MYCT1 myc target 1 1.22692
PCNA proliferating cell nuclear antigen 1.20785
MIS18BP1 MIS18 binding protein 1 1.20439
BIRC5 baculoviral IAP repeat containing 5 1.19834
CCND1 cyclin D1 1.16735
STOML2 stomatin (EPB72)-like 2 1.13882
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 1.12909
EGFR epidermal growth factor receptor 1.09713
CDKN2A cyclin-dependent kinase inhibitor 2A 1.08327
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 1.01638
ZNF706 zinc finger protein 706 0.955779
CD82 CD82 molecule 0.937044
GSTTP1 glutathione S-transferase theta pseudogene 1 0.908965
GSTT1 glutathione S-transferase theta 1 0.908965
ZFX zinc finger protein, X-linked 0.906498
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.869187
SH3GL2 SH3-domain GRB2-like 2 0.813052
FHIT fragile histidine triad 0.795411
TERT telomerase reverse transcriptase 0.770435
ZMYND11 zinc finger, MYND-type containing 11 0.761862
PRR20E proline rich 20E 0.760639
PRR20C proline rich 20C 0.760639
CALML3 calmodulin-like 3 0.753713
MIR21 microRNA 21 0.746391
PRR20A proline rich 20A 0.73746
FSCN3 fascin actin-bundling protein 3, testicular 0.736649
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.736243
STK17A serine/threonine kinase 17a 0.714005
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 0.708767
FSCN2 fascin actin-bundling protein 2, retinal 0.708364
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.701928
GSTM3 glutathione S-transferase mu 3 (brain) 0.689893
BCL2 B-cell CLL/lymphoma 2 0.682294
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.677504
TFG TRK-fused gene 0.674315
MCM7 minichromosome maintenance complex component 7 0.673917
MMP2 matrix metallopeptidase 2 0.671527
LY6D lymphocyte antigen 6 complex, locus D 0.664372
CHD5 chromodomain helicase DNA binding protein 5 0.649718
GSTM1 glutathione S-transferase mu 1 0.648138
IFNA17 interferon, alpha 17 0.646953
MTDH metadherin 0.644981
PTEN phosphatase and tensin homolog 0.643797
EIF4E eukaryotic translation initiation factor 4E 0.635921
MCM2 minichromosome maintenance complex component 2 0.623359
VEGFC vascular endothelial growth factor C 0.613183
FSCN1 fascin actin-bundling protein 1 0.606933
PCDH17 protocadherin 17 0.606152
ENG endoglin 0.585887
KRT13 keratin 13, type I 0.58433
ITGA8 integrin, alpha 8 0.579661
MIR93 microRNA 93 0.575383
BCAR3 breast cancer anti-estrogen resistance 3 0.573439
CCL19 chemokine (C-C motif) ligand 19 0.550522
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.549747
MAGEA9B melanoma antigen family A9B 0.548583
MAGEA9 melanoma antigen family A9 0.548583
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.547807
CTSD cathepsin D 0.547419
KRT31 keratin 31, type I 0.542379
S100A2 S100 calcium binding protein A2 0.535796
COPS5 COP9 signalosome subunit 5 0.528063
GSTM4 glutathione S-transferase mu 4 0.527676
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.521502
MKI67 marker of proliferation Ki-67 0.517649
MAL mal, T-cell differentiation protein 0.517649
IFNA21 interferon, alpha 21 0.514956
SP140 SP140 nuclear body protein 0.506507
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.50459
EMILIN1 elastin microfibril interfacer 1 0.503058
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.491978
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 0.490835
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.487407
USP22 ubiquitin specific peptidase 22 0.485885
DAPK1 death-associated protein kinase 1 0.483224
ACAN aggrecan 0.481325
BAX BCL2-associated X protein 0.479427
CCL21 chemokine (C-C motif) ligand 21 0.476014
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.475255
PFDN4 prefoldin subunit 4 0.462772
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.462016
CCR6 chemokine (C-C motif) receptor 6 0.461261
MUS81 MUS81 structure-specific endonuclease subunit 0.442042
VEGFA vascular endothelial growth factor A 0.440914
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.438282
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.436026
STC2 stanniocalcin 2 0.433772
ANG angiogenin, ribonuclease, RNase A family, 5 0.429642
MMP9 matrix metallopeptidase 9 0.427765
MFAP2 microfibrillar-associated protein 2 0.423265
MCM4 minichromosome maintenance complex component 4 0.423265
CTCF CCCTC-binding factor (zinc finger protein) 0.416521
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 0.415024
S100A8 S100 calcium binding protein A8 0.413153
PLAGL2 pleiomorphic adenoma gene-like 2 0.412779
HMGB1 high mobility group box 1 0.408666
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.407545
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.403064
CCL20 chemokine (C-C motif) ligand 20 0.400453
BMF Bcl2 modifying factor 0.394491
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 0.394491
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.393374
FOXM1 forkhead box M1 0.393001
EZR ezrin 0.392629
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.384822
MMP15 matrix metallopeptidase 15 (membrane-inserted) 0.384822
NDRG1 N-myc downstream regulated 1 0.382223
IRF6 interferon regulatory factor 6 0.374438
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.372958
CD44 CD44 molecule (Indian blood group) 0.371847
PTK6 protein tyrosine kinase 6 0.370368
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.367779
GSTA3 glutathione S-transferase alpha 3 0.36741
CD109 CD109 molecule 0.366301
GSTA2 glutathione S-transferase alpha 2 0.366301
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.365932
GSTA4 glutathione S-transferase alpha 4 0.365193
HPGDS hematopoietic prostaglandin D synthase 0.365193
EGFL7 EGF-like-domain, multiple 7 0.363347
PDPN podoplanin 0.362609
GSTA1 glutathione S-transferase alpha 1 0.359289
HBA1 hemoglobin, alpha 1 0.349349
ELAVL1 ELAV like RNA binding protein 1 0.346777
TSPO translocator protein (18kDa) 0.340539
TENM1 teneurin transmembrane protein 1 0.336876
AURKA aurora kinase A 0.334315
SENP1 SUMO1/sentrin specific peptidase 1 0.333949
MMP20 matrix metallopeptidase 20 0.33066
CCNG2 cyclin G2 0.330295
HBA2 hemoglobin, alpha 2 0.328105
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.323002
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.321181
PDCD5 programmed cell death 5 0.320454
CCR7 chemokine (C-C motif) receptor 7 0.313915
CDK2 cyclin-dependent kinase 2 0.313189
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.310652
CD34 CD34 molecule 0.307033
PCDH11Y protocadherin 11 Y-linked 0.307033
PROM1 prominin 1 0.305948
MCM3 minichromosome maintenance complex component 3 0.305226
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.30342
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.298731
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.297651
CTCFL CCCTC-binding factor (zinc finger protein)-like 0.292975
LGALS8 lectin, galactoside-binding, soluble, 8 0.289386
KRT8 keratin 8, type II 0.287952
VCAN versican 0.287235
GP5 glycoprotein V (platelet) 0.28616
SATB2 SATB homeobox 2 0.283655
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.28294
ITGB8 integrin, beta 8 0.27687
CCNG1 cyclin G1 0.270464
DNTT DNA nucleotidylexotransferase 0.267267
ADCY6 adenylate cyclase 6 0.265849
PCDH11X protocadherin 11 X-linked 0.264785
ING1 inhibitor of growth family, member 1 0.263014
PLAU plasminogen activator, urokinase 0.263014
MLH3 mutL homolog 3 0.261599
MIR19A microRNA 19a 0.260538
CD200R1 CD200 receptor 1 0.258417
CCNB1 cyclin B1 0.257005
DCN decorin 0.254888
ZFY zinc finger protein, Y-linked 0.254888
LGALS3 lectin, galactoside-binding, soluble, 3 0.254183
PXN paxillin 0.25207
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.249608
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.249257
MYBPC1 myosin binding protein C, slow type 0.248905
MST1 macrophage stimulating 1 0.248554
SATB1 SATB homeobox 1 0.24715
INPPL1 inositol polyphosphate phosphatase-like 1 0.233878
TAPBP TAP binding protein (tapasin) 0.23353
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.231102
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.22937
MGMT O-6-methylguanine-DNA methyltransferase 0.226952
ERBB2 erb-b2 receptor tyrosine kinase 2 0.225573
S100A11 S100 calcium binding protein A11 0.221108
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.220081
PLK2 polo-like kinase 2 0.218034
KLK11 kallikrein-related peptidase 11 0.213959
GSTM2 glutathione S-transferase mu 2 (muscle) 0.213283
MAPK3 mitogen-activated protein kinase 3 0.212945
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.212608
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.211934
ARHGAP1 Rho GTPase activating protein 1 0.210253
BST2 bone marrow stromal cell antigen 2 0.200331
CD6 CD6 molecule 0.199033
ACTB actin, beta 0.195183
SOX2 SRY (sex determining region Y)-box 2 0.194548
RBP1 retinol binding protein 1, cellular 0.189244
KRT4 keratin 4, type II 0.188938
CXCR4 chemokine (C-X-C motif) receptor 4 0.18651
CCND3 cyclin D3 0.18651
IGFBP7 insulin-like growth factor binding protein 7 0.182957
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.182375
ACOT13 acyl-CoA thioesterase 13 0.176485
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.173832
ENDOG endonuclease G 0.173314
MIR203A microRNA 203a 0.172291
ACTG1 actin gamma 1 0.172038
KLK4 kallikrein-related peptidase 4 0.170789
ITGAV integrin, alpha V 0.170299
CCNA1 cyclin A1 0.169571
FOXP3 forkhead box P3 0.16933
STC1 stanniocalcin 1 0.16933
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.168381
MLH1 mutL homolog 1 0.167224
MMP12 matrix metallopeptidase 12 0.165655
MET MET proto-oncogene, receptor tyrosine kinase 0.165217
CFL1 cofilin 1 (non-muscle) 0.163729
KRT9 keratin 9, type I 0.163523
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.159124
BIRC7 baculoviral IAP repeat containing 7 0.158605
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.157929