laryngeal carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A larynx cancer that has_material_basis_in epithelial cells. (Human Disease Ontology, DOID_2600)
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Genes

321 genes co-occuring with the disease laryngeal carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TP53 tumor protein p53 1.60502
GGNBP2 gametogenetin binding protein 2 1.41753
PCNA proliferating cell nuclear antigen 1.27563
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 1.25602
BIRC5 baculoviral IAP repeat containing 5 1.25602
CCND1 cyclin D1 1.21782
PDPN podoplanin 1.19489
EGFR epidermal growth factor receptor 1.12572
CAMSAP1 calmodulin regulated spectrin-associated protein 1 1.07992
MYCT1 myc target 1 1.0795
MIS18BP1 MIS18 binding protein 1 1.05765
NBL1 neuroblastoma 1, DAN family BMP antagonist 1.05093
TFG TRK-fused gene 1.04251
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.04125
CDKN2A cyclin-dependent kinase inhibitor 2A 1.04083
DHRS11 dehydrogenase/reductase (SDR family) member 11 0.994861
STOML2 stomatin (EPB72)-like 2 0.993174
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 0.983479
MMP2 matrix metallopeptidase 2 0.947019
BCL2 B-cell CLL/lymphoma 2 0.925452
GSTTP1 glutathione S-transferase theta pseudogene 1 0.925039
GSTT1 glutathione S-transferase theta 1 0.925039
RPL24 ribosomal protein L24 0.909787
VEGFC vascular endothelial growth factor C 0.908965
EIF4E eukaryotic translation initiation factor 4E 0.896641
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.872462
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.824948
MIR93 microRNA 93 0.820026
ZNF706 zinc finger protein 706 0.813462
CD82 CD82 molecule 0.795002
FHIT fragile histidine triad 0.794181
PROM1 prominin 1 0.783116
MKI67 marker of proliferation Ki-67 0.770435
ZFX zinc finger protein, X-linked 0.764718
GSTM1 glutathione S-transferase mu 1 0.759824
PTEN phosphatase and tensin homolog 0.74883
GSTM3 glutathione S-transferase mu 3 (brain) 0.74761
MIR21 microRNA 21 0.745985
FOXN3 forkhead box N3 0.745578
CTSD cathepsin D 0.740705
TERT telomerase reverse transcriptase 0.733811
CD44 CD44 molecule (Indian blood group) 0.732191
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.727333
BAX BCL2-associated X protein 0.721673
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.71925
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.714005
MMP9 matrix metallopeptidase 9 0.71078
ENG endoglin 0.708364
TCHP trichoplein, keratin filament binding 0.700722
BRMS1 breast cancer metastasis suppressor 1 0.695504
BRMS1L breast cancer metastasis-suppressor 1-like 0.694301
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.686691
LCE3D late cornified envelope 3D 0.686291
RPL31 ribosomal protein L31 0.67312
SH3GL2 SH3-domain GRB2-like 2 0.672722
ECM1 extracellular matrix protein 1 0.663578
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.650903
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.642615
TGM3 transglutaminase 3 0.641433
ZMYND11 zinc finger, MYND-type containing 11 0.623359
PRR20C proline rich 20C 0.622183
PRR20E proline rich 20E 0.622183
CALML3 calmodulin-like 3 0.615529
COPS5 COP9 signalosome subunit 5 0.611229
S100A2 S100 calcium binding protein A2 0.607714
KIF14 kinesin family member 14 0.60147
PRR20A proline rich 20A 0.59952
FSCN3 fascin actin-bundling protein 3, testicular 0.59913
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.597961
EGFL7 EGF-like-domain, multiple 7 0.595623
ILK integrin-linked kinase 0.587054
MIR203A microRNA 203a 0.586276
CHSY3 chondroitin sulfate synthase 3 0.585887
STK17A serine/threonine kinase 17a 0.577327
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 0.572273
FLT4 fms-related tyrosine kinase 4 0.571884
FSCN2 fascin actin-bundling protein 2, retinal 0.571495
VEGFA vascular endothelial growth factor A 0.571107
ELAVL1 ELAV like RNA binding protein 1 0.569552
ACAN aggrecan 0.560616
PLAU plasminogen activator, urokinase 0.550911
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.541992
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.53928
MCM7 minichromosome maintenance complex component 7 0.538506
ZNF135 zinc finger protein 135 0.535796
LY6D lymphocyte antigen 6 complex, locus D 0.529222
CD200R1 CD200 receptor 1 0.517649
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.516879
LGALS8 lectin, galactoside-binding, soluble, 8 0.516879
CHD5 chromodomain helicase DNA binding protein 5 0.514956
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.513417
IFNA17 interferon, alpha 17 0.512264
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.51188
DKKL1 dickkopf-like 1 0.510728
MTDH metadherin 0.510344
GSTA3 glutathione S-transferase alpha 3 0.50689
VCAN versican 0.506123
GSTA2 glutathione S-transferase alpha 2 0.505739
GSTA4 glutathione S-transferase alpha 4 0.504207
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.501909
GSTA1 glutathione S-transferase alpha 1 0.498467
CD6 CD6 molecule 0.494266
NCL nucleolin 0.490072
MCM2 minichromosome maintenance complex component 2 0.48893
CDK2 cyclin-dependent kinase 2 0.484364
HMGB1 high mobility group box 1 0.483604
FSCN1 fascin actin-bundling protein 1 0.472982
PCDH17 protocadherin 17 0.472604
TIMP1 TIMP metallopeptidase inhibitor 1 0.463149
MET MET proto-oncogene, receptor tyrosine kinase 0.458996
ANG angiogenin, ribonuclease, RNase A family, 5 0.45447
KRT13 keratin 13, type I 0.451454
S100A3 S100 calcium binding protein A3 0.446558
ITGA8 integrin, alpha 8 0.446558
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.446182
BCAR3 breast cancer anti-estrogen resistance 3 0.440538
RHOQ ras homolog family member Q 0.440162
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 0.437906
DCN decorin 0.435651
S100A11 S100 calcium binding protein A11 0.42664
BSG basigin (Ok blood group) 0.425514
CCL19 chemokine (C-C motif) ligand 19 0.418768
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.417644
MAGEA9B melanoma antigen family A9B 0.416896
MAGEA9 melanoma antigen family A9 0.416896
EZR ezrin 0.411657
KRT31 keratin 31, type I 0.410909
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.407172
RPE ribulose-5-phosphate-3-epimerase 0.406798
RBP1 retinol binding protein 1, cellular 0.406798
TSPO translocator protein (18kDa) 0.397843
GSTM4 glutathione S-transferase mu 4 0.396725
MMP1 matrix metallopeptidase 1 0.391885
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.390769
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.389653
MAL mal, T-cell differentiation protein 0.387051
IFNA21 interferon, alpha 21 0.384079
GPR176 G protein-coupled receptor 176 0.382223
LVRN laeverin 0.382223
ITGAV integrin, alpha V 0.381481
SSNA1 Sjogren syndrome nuclear autoantigen 1 0.379626
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 0.379256
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.378885
TADA3 transcriptional adaptor 3 0.377773
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 0.377031
SP140 SP140 nuclear body protein 0.37629
ANXA5 annexin A5 0.37592
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.37555
EMILIN1 elastin microfibril interfacer 1 0.372958
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.370368
AHNAK AHNAK nucleoprotein 0.368149
RARB retinoic acid receptor, beta 0.367779
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.36741
ULBP3 UL16 binding protein 3 0.365932
ERBB2 erb-b2 receptor tyrosine kinase 2 0.365193
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 0.361133
USP22 ubiquitin specific peptidase 22 0.355972
DAPK1 death-associated protein kinase 1 0.353763
CD83 CD83 molecule 0.346777
CCL21 chemokine (C-C motif) ligand 21 0.346777
CA9 carbonic anhydrase IX 0.33944
PCCA propionyl CoA carboxylase, alpha polypeptide 0.333949
MTA1 metastasis associated 1 0.333949
PFDN4 prefoldin subunit 4 0.333949
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.333218
CCR6 chemokine (C-C motif) receptor 6 0.332487
CCR7 chemokine (C-C motif) receptor 7 0.332487
ADAM12 ADAM metallopeptidase domain 12 0.33066
GCAT glycine C-acetyltransferase 0.32993
RHOB ras homolog family member B 0.3292
RUNX3 runt-related transcription factor 3 0.321545
MUS81 MUS81 structure-specific endonuclease subunit 0.313915
CD200 CD200 molecule 0.313552
HBA1 hemoglobin, alpha 1 0.312464
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.312464
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.308118
OGN osteoglycin 0.307395
STC2 stanniocalcin 2 0.305948
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.303781
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.301615
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.300894
S100A4 S100 calcium binding protein A4 0.297291
MFAP2 microfibrillar-associated protein 2 0.295851
MCM4 minichromosome maintenance complex component 4 0.295851
ACOT13 acyl-CoA thioesterase 13 0.295042
HBA2 hemoglobin, alpha 2 0.291539
TIMP2 TIMP metallopeptidase inhibitor 2 0.290821
CTCF CCCTC-binding factor (zinc finger protein) 0.289386
SOCS1 suppressor of cytokine signaling 1 0.289386
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 0.287952
S100A8 S100 calcium binding protein A8 0.285802
PLAGL2 pleiomorphic adenoma gene-like 2 0.285802
S100A7 S100 calcium binding protein A7 0.285086
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.285086
MT1E metallothionein 1E 0.280439
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.276514
BAG1 BCL2-associated athanogene 0.276158
CCL20 chemokine (C-C motif) ligand 20 0.273664
RPL22 ribosomal protein L22 0.272953
LGALS3 lectin, galactoside-binding, soluble, 3 0.272241
CA1 carbonic anhydrase I 0.27153
TRAF3 TNF receptor-associated factor 3 0.268687
BMF Bcl2 modifying factor 0.268332
HLA-A major histocompatibility complex, class I, A 0.267622
FOXM1 forkhead box M1 0.266913
HPGDS hematopoietic prostaglandin D synthase 0.261245
MMP15 matrix metallopeptidase 15 (membrane-inserted) 0.25877
NDRG1 N-myc downstream regulated 1 0.256652
AMY1B amylase, alpha 1B (salivary) 0.25207
AMY1C amylase, alpha 1C (salivary) 0.25207
AMY1A amylase, alpha 1A (salivary) 0.25207
HDAC6 histone deacetylase 6 0.251718
IRF6 interferon regulatory factor 6 0.249257
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.247852
ACTB actin, beta 0.24715
SOX2 SRY (sex determining region Y)-box 2 0.245396
PTK6 protein tyrosine kinase 6 0.245396
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.245046
DUSP4 dual specificity phosphatase 4 0.244696
MMP12 matrix metallopeptidase 12 0.241546
CD109 CD109 molecule 0.241546
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.241196
TMPRSS13 transmembrane protease, serine 13 0.240148
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 0.240148
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.239799
CXCR4 chemokine (C-X-C motif) receptor 4 0.236312
CAPN10 calpain 10 0.234225
CD34 CD34 molecule 0.233878
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.233183
IFNA2 interferon, alpha 2 0.232836
DNTT DNA nucleotidylexotransferase 0.232836
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.232489
HLA-C major histocompatibility complex, class I, C 0.229716
CD4 CD4 molecule 0.229024
FOXP3 forkhead box P3 0.226952
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.220081
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.219398
ACTG1 actin gamma 1 0.219398
KRT8 keratin 8, type II 0.217352
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.213959
TENM1 teneurin transmembrane protein 1 0.213621
AURKA aurora kinase A 0.211597
SENP1 SUMO1/sentrin specific peptidase 1 0.211261
MMP20 matrix metallopeptidase 20 0.208245
CCNG2 cyclin G2 0.207912
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.206913
KRT4 keratin 4, type II 0.205254
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 0.202618
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.201308
CSTB cystatin B (stefin B) 0.200656
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.199681
ATM ATM serine/threonine kinase 0.199681
AQP1 aquaporin 1 (Colton blood group) 0.199033
PDCD5 programmed cell death 5 0.198709
TGFB1 transforming growth factor, beta 1 0.197742
ZYX zyxin 0.191719
HSPA4 heat shock 70kDa protein 4 0.190786
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.190476
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 0.189244
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.188326
PCDH11Y protocadherin 11 Y-linked 0.187415
MCM3 minichromosome maintenance complex component 3 0.18591
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.184424
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.180652
OXA1L oxidase (cytochrome c) assembly 1-like 0.179802
CTCFL CCCTC-binding factor (zinc finger protein)-like 0.175947
A4GALT alpha 1,4-galactosyltransferase 0.174881
HRAS Harvey rat sarcoma viral oncogene homolog 0.173832
BCL2L1 BCL2-like 1 0.171286
GP5 glycoprotein V (platelet) 0.171286
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.170544
BTG2 BTG family, member 2 0.170299
MIR10A microRNA 10a 0.170054
SATB2 SATB homeobox 2 0.169571
COL4A2 collagen, type IV, alpha 2 0.166768
ITGB8 integrin, beta 8 0.165217
ERBB3 erb-b2 receptor tyrosine kinase 3 0.163317
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.163317
CCNG1 cyclin G1 0.161523
PRKCZ protein kinase C, zeta 0.161523
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.159302
ADCY6 adenylate cyclase 6 0.159124
PCDH11X protocadherin 11 X-linked 0.158605
RERE arginine-glutamic acid dipeptide (RE) repeats 0.158097
MLH1 mutL homolog 1 0.157929
ING1 inhibitor of growth family, member 1 0.157765
CNN1 calponin 1, basic, smooth muscle 0.148017
TAGLN transgelin 0.144607
MLH3 mutL homolog 3 0.134457
MIR19A microRNA 19a 0.134408
CCNB1 cyclin B1 0.134244
ZFY zinc finger protein, Y-linked 0.134143
PXN paxillin 0.134008
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.13387
MYBPC1 myosin binding protein C, slow type 0.133853
MST1 macrophage stimulating 1 0.133835
SATB1 SATB homeobox 1 0.133765
INPPL1 inositol polyphosphate phosphatase-like 1 0.133074
TAPBP TAP binding protein (tapasin) 0.133055
MGMT O-6-methylguanine-DNA methyltransferase 0.132687
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.132286
PLK2 polo-like kinase 2 0.132162
KLK11 kallikrein-related peptidase 11 0.13191
GSTM2 glutathione S-transferase mu 2 (muscle) 0.131867
MAPK3 mitogen-activated protein kinase 3 0.131846
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.131824
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.131781
ARHGAP1 Rho GTPase activating protein 1 0.131673
BST2 bone marrow stromal cell antigen 2 0.130999
CCND3 cyclin D3 0.129927
IGFBP7 insulin-like growth factor binding protein 7 0.129616
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.129563
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.128715
ENDOG endonuclease G 0.128658
KLK4 kallikrein-related peptidase 4 0.128371
CCNA1 cyclin A1 0.128224
STC1 stanniocalcin 1 0.128195
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.128078
CFL1 cofilin 1 (non-muscle) 0.127435
KRT9 keratin 9, type I 0.127404
BIRC7 baculoviral IAP repeat containing 7 0.126564