large latent transforming growth factor-beta complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors. (Gene Ontology, GO_0038045)
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35 proteins co-occuring with the large latent transforming growth factor-beta complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
LTBP1 latent transforming growth factor beta binding protein 1 2.85753
LTBP3 latent transforming growth factor beta binding protein 3 1.67933
TGFB1 transforming growth factor, beta 1 1.66538
LTBP2 latent transforming growth factor beta binding protein 2 1.65513
LTBP4 latent transforming growth factor beta binding protein 4 1.48079
FBN1 fibrillin 1 1.07663
LRRC32 leucine rich repeat containing 32 0.913909
FBN3 fibrillin 3 0.850665
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 0.827712
SRRM1 serine/arginine repetitive matrix 1 0.785071
PDLIM4 PDZ and LIM domain 4 0.720351
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.630318
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 0.620529
FBN2 fibrillin 2 0.601066
MMRN1 multimerin 1 0.565508
PDIA6 protein disulfide isomerase family A, member 6 0.530847
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 0.503506
TGM2 transglutaminase 2 0.503099
TGFBR1 transforming growth factor, beta receptor 1 0.458803
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.447656
MFAP2 microfibrillar-associated protein 2 0.437356
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.402081
TGFB2 transforming growth factor, beta 2 0.388137
SMAD2 SMAD family member 2 0.352142
BMP1 bone morphogenetic protein 1 0.307004
CHRD chordin 0.303655
MMP3 matrix metallopeptidase 3 0.290678
SCN10A sodium channel, voltage gated, type X alpha subunit 0.265311
PLG plasminogen 0.225976
SDC4 syndecan 4 0.203361
MMP2 matrix metallopeptidase 2 0.190814
ALPPL2 alkaline phosphatase, placental-like 2 0.188274
ALPL alkaline phosphatase, liver/bone/kidney 0.187646
ALPP alkaline phosphatase, placental 0.187333
CMA1 chymase 1, mast cell 0.164315