large cell neuroendocrine carcinoma cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Large-cell neuroendocrine carcinoma is now recognized as an histologically high-grade non-small cell carcinoma showing histopathological features of neuroendocrine differentiation as well as immunohistochemical neuroendocrine markers. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004833)
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Genes

71 proteins co-occuring with the tissue large cell neuroendocrine carcinoma cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
SYP synaptophysin 1.98366
CHGA chromogranin A 1.80463
NCAM1 neural cell adhesion molecule 1 1.42229
NKX2-1 NK2 homeobox 1 1.40156
ENO2 enolase 2 (gamma, neuronal) 1.35449
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 1.26979
LCN1 lipocalin 1 1.25101
ADGRB3 adhesion G protein-coupled receptor B3 1.14963
KRT7 keratin 7, type II 1.05677
TP53 tumor protein p53 1.02995
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 0.967225
VIL1 villin 1 0.924194
KRT20 keratin 20, type I 0.893921
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.872327
MEN1 multiple endocrine neoplasia I 0.856312
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.837414
CNN1 calponin 1, basic, smooth muscle 0.825686
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.770685
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 0.75495
CDKN2A cyclin-dependent kinase inhibitor 2A 0.752884
PCBP1 poly(rC) binding protein 1 0.711729
SFN stratifin 0.699444
UBE2C ubiquitin-conjugating enzyme E2C 0.685143
FSCN1 fascin actin-bundling protein 1 0.67495
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.670471
FSCN3 fascin actin-bundling protein 3, testicular 0.633953
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.627485
FSCN2 fascin actin-bundling protein 2, retinal 0.620621
NNAT neuronatin 0.60249
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.588431
NAPSA napsin A aspartic peptidase 0.568823
KRT18 keratin 18, type I 0.562441
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 0.55607
EGFR epidermal growth factor receptor 0.555671
TAGLN transgelin 0.519647
UMPS uridine monophosphate synthetase 0.518859
MIR21 microRNA 21 0.491791
ASCL1 achaete-scute family bHLH transcription factor 1 0.489447
SST somatostatin 0.485156
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.472704
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.468048
GSTM3 glutathione S-transferase mu 3 (brain) 0.456055
UPK3A uroplakin 3A 0.447192
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.433757
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.425726
CCND1 cyclin D1 0.424963
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.414673
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.409351
E2F1 E2F transcription factor 1 0.405935
SSTR3 somatostatin receptor 3 0.400628
MKI67 marker of proliferation Ki-67 0.387027
VGF VGF nerve growth factor inducible 0.360036
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.360036
GP5 glycoprotein V (platelet) 0.359292
BAX BCL2-associated X protein 0.352227
KRT5 keratin 5, type II 0.338914
ERBB2 erb-b2 receptor tyrosine kinase 2 0.337808
SSTR5 somatostatin receptor 5 0.32132
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.301758
AMACR alpha-methylacyl-CoA racemase 0.282837
GP6 glycoprotein VI (platelet) 0.279307
RB1 retinoblastoma 1 0.275094
CAV2 caveolin 2 0.262645
SSTR1 somatostatin receptor 1 0.247399
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.243918
ERCC1 excision repair cross-complementation group 1 0.240826
TRAF3 TNF receptor-associated factor 3 0.23459
CRHR2 corticotropin releasing hormone receptor 2 0.232881
MET MET proto-oncogene, receptor tyrosine kinase 0.232317
HK1 hexokinase 1 0.223177
DPYD dihydropyrimidine dehydrogenase 0.213833