large cell lung cancer cell line Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
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Genes

233 proteins co-occuring with the tissue large cell lung cancer cell line in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
ADPGK ADP-dependent glucokinase 1.64506
TP53 tumor protein p53 1.57748
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.46868
BAX BCL2-associated X protein 1.33003
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.21001
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.202
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.19445
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.18823
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.1585
PARP1 poly (ADP-ribose) polymerase 1 1.1359
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 1.11597
RNF111 ring finger protein 111 1.1142
BCL2L1 BCL2-like 1 1.10579
BIRC5 baculoviral IAP repeat containing 5 1.09739
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 1.08722
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) 1.08457
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.0828
FAM133A family with sequence similarity 133, member A 1.05237
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase 1.04005
CCPG1 cell cycle progression 1 1.01156
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.992379
CDCA7L cell division cycle associated 7-like 0.985859
ANXA5 annexin A5 0.971984
TOP1 topoisomerase (DNA) I 0.944796
BCL2 B-cell CLL/lymphoma 2 0.928906
WBSCR22 Williams Beuren syndrome chromosome region 22 0.923339
SESN2 sestrin 2 0.899445
EGFR epidermal growth factor receptor 0.887557
CAV1 caveolin 1, caveolae protein, 22kDa 0.885862
TSPYL5 TSPY-like 5 0.852948
TP53I3 tumor protein p53 inducible protein 3 0.840349
DDIT3 DNA-damage-inducible transcript 3 0.838672
CCNB1 cyclin B1 0.836156
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 0.830291
TAGLN2 transgelin 2 0.823175
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 0.806047
TSPYL4 TSPY-like 4 0.803961
KIAA1524 KIAA1524 0.795624
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.789796
EIF4H eukaryotic translation initiation factor 4H 0.772759
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.7711
H2AFX H2A histone family, member X 0.732265
CDK1 cyclin-dependent kinase 1 0.722809
MDM4 MDM4, p53 regulator 0.721988
TCTEX1D4 Tctex1 domain containing 4 0.711729
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.703127
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.692085
FADD Fas (TNFRSF6)-associated via death domain 0.682287
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.676987
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 0.66925
ROMO1 reactive oxygen species modulator 1 0.658678
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.653807
ATG5 autophagy related 5 0.651777
EML4 echinoderm microtubule associated protein like 4 0.648938
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.648532
CCAR1 cell division cycle and apoptosis regulator 1 0.644884
CDC25C cell division cycle 25C 0.637594
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.635167
RARG retinoic acid receptor, gamma 0.630718
SKIL SKI-like proto-oncogene 0.626677
PDIA4 protein disulfide isomerase family A, member 4 0.625061
HDAC4 histone deacetylase 4 0.624658
MDC1 mediator of DNA-damage checkpoint 1 0.624254
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.622235
BECN1 beclin 1, autophagy related 0.606514
CDK4 cyclin-dependent kinase 4 0.594853
DIABLO diablo, IAP-binding mitochondrial protein 0.594853
TUBA1B tubulin, alpha 1b 0.592845
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.589234
MIR98 microRNA 98 0.587228
DDIT4 DNA-damage-inducible transcript 4 0.584422
ZNF148 zinc finger protein 148 0.574816
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.567626
PLK2 polo-like kinase 2 0.565631
PTEN phosphatase and tensin homolog 0.563238
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.561245
CERS2 ceramide synthase 2 0.559254
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.55408
SARS seryl-tRNA synthetase 0.550901
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 0.550901
SNW1 SNW domain containing 1 0.546533
FHIT fragile histidine triad 0.543756
KRAS Kirsten rat sarcoma viral oncogene homolog 0.542963
DUSP1 dual specificity phosphatase 1 0.54217
HRAS Harvey rat sarcoma viral oncogene homolog 0.541773
FBXO17 F-box protein 17 0.541377
CLSPN claspin 0.539396
DCK deoxycytidine kinase 0.521223
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.515317
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 0.515317
RUNX3 runt-related transcription factor 3 0.515317
FASLG Fas ligand (TNF superfamily, member 6) 0.505495
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.498048
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 0.497266
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.494918
CDC25B cell division cycle 25B 0.490619
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.489447
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.485545
COL18A1 collagen, type XVIII, alpha 1 0.478145
GADD45A growth arrest and DNA-damage-inducible, alpha 0.475812
TOPBP1 topoisomerase (DNA) II binding protein 1 0.471151
FAF1 Fas (TNFRSF6) associated factor 1 0.466885
CCND1 cyclin D1 0.462239
ATM ATM serine/threonine kinase 0.461465
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.447961
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.445653
IL17RA interleukin 17 receptor A 0.442962
MMP2 matrix metallopeptidase 2 0.432991
SFN stratifin 0.432608
MAPRE1 microtubule-associated protein, RP/EB family, member 1 0.428401
CLIC4 chloride intracellular channel 4 0.423054
DRD5 dopamine receptor D5 0.421148
DKK4 dickkopf WNT signaling pathway inhibitor 4 0.414673
CA4 carbonic anhydrase IV 0.41087
HDAC9 histone deacetylase 9 0.408592
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.405935
XBP1 X-box binding protein 1 0.399492
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.387027
IGFBP3 insulin-like growth factor binding protein 3 0.385143
TRAF4 TNF receptor-associated factor 4 0.38326
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 0.380627
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.378372
CDK2 cyclin-dependent kinase 2 0.377621
RARB retinoic acid receptor, beta 0.377621
CETN2 centrin, EF-hand protein, 2 0.374618
AXIN1 axin 1 0.372369
MET MET proto-oncogene, receptor tyrosine kinase 0.370121
NQO1 NAD(P)H dehydrogenase, quinone 1 0.368624
MVD mevalonate (diphospho) decarboxylase 0.368624
CTNND1 catenin (cadherin-associated protein), delta 1 0.368624
OCA2 oculocutaneous albinism II 0.366007
THAP1 THAP domain containing, apoptosis associated protein 1 0.362646
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.35743
DDB2 damage-specific DNA binding protein 2, 48kDa 0.35557
BACE2 beta-site APP-cleaving enzyme 2 0.353712
SFRP1 secreted frizzled-related protein 1 0.351114
YBX3 Y box binding protein 3 0.350372
HK2 hexokinase 2 0.350372
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.348889
VDAC2 voltage-dependent anion channel 2 0.348148
HDAC3 histone deacetylase 3 0.346298
GDF15 growth differentiation factor 15 0.345188
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 0.344818
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.338914
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.338177
AKAP12 A kinase (PRKA) anchor protein 12 0.331927
MGMT O-6-methylguanine-DNA methyltransferase 0.331194
TGFBR3 transforming growth factor, beta receptor III 0.329361
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 0.327713
FDXR ferredoxin reductase 0.325335
SBDS Shwachman-Bodian-Diamond syndrome 0.32205
PTK6 protein tyrosine kinase 6 0.320956
INHBA inhibin, beta A 0.320956
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 0.31877
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.318042
GSK3A glycogen synthase kinase 3 alpha 0.311145
RXRA retinoid X receptor, alpha 0.308974
STK38 serine/threonine kinase 38 0.306805
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 0.306444
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.303919
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 0.303198
BIRC2 baculoviral IAP repeat containing 2 0.302838
CLIC1 chloride intracellular channel 1 0.302478
ADAM8 ADAM metallopeptidase domain 8 0.301039
HDAC8 histone deacetylase 8 0.293508
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.290295
YARS tyrosyl-tRNA synthetase 0.283191
IL24 interleukin 24 0.281776
YY1 YY1 transcription factor 0.278603
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.278603
PLK1 polo-like kinase 1 0.277197
BMPR1B bone morphogenetic protein receptor, type IB 0.276846
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.275444
EIF4B eukaryotic translation initiation factor 4B 0.263669
CRYZ crystallin, zeta (quinone reductase) 0.263327
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.255567
MMP7 matrix metallopeptidase 7 0.255234
CCNE2 cyclin E2 0.255234
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.25457
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.250953
HYOU1 hypoxia up-regulated 1 0.248683
PNMA1 paraneoplastic Ma antigen 1 0.244232
CDKN2A cyclin-dependent kinase inhibitor 2A 0.242983
AMER1 APC membrane recruitment protein 1 0.240826
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.239913
DNTT DNA nucleotidylexotransferase 0.23781
DYNLT1 dynein, light chain, Tctex-type 1 0.232881
ACTC1 actin, alpha, cardiac muscle 1 0.232317
CCND3 cyclin D3 0.232039
GMNN geminin, DNA replication inhibitor 0.232039
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.227445
TOP2B topoisomerase (DNA) II beta 180kDa 0.226667
EGR1 early growth response 1 0.225144
ADM2 adrenomedullin 2 0.22415
TIMELESS timeless circadian clock 0.223662
ERCC4 excision repair cross-complementation group 4 0.22246
TXNL1 thioredoxin-like 1 0.221521
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.219928
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.219047
CAT catalase 0.21883
PKM pyruvate kinase, muscle 0.218398
CHEK1 checkpoint kinase 1 0.218398
SIL1 SIL1 nucleotide exchange factor 0.218186
ERCC5 excision repair cross-complementation group 5 0.215534
TUBB4B tubulin, beta 4B class IVb 0.215534
CXCL3 chemokine (C-X-C motif) ligand 3 0.215341
CXCL12 chemokine (C-X-C motif) ligand 12 0.215147
IGF1R insulin-like growth factor 1 receptor 0.214576
AMBP alpha-1-microglobulin/bikunin precursor 0.21033
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.195897
CFLAR CASP8 and FADD-like apoptosis regulator 0.195122
UBC ubiquitin C 0.194117
RPS27A ribosomal protein S27a 0.193964
UBB ubiquitin B 0.193409
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.193124
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.192599
MIR21 microRNA 21 0.190271
HDAC1 histone deacetylase 1 0.187056
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.186351
CD59 CD59 molecule, complement regulatory protein 0.18554
GSTP1 glutathione S-transferase pi 1 0.184308
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.17672
H3F3B H3 histone, family 3B (H3.3B) 0.176364
H3F3A H3 histone, family 3A 0.176364
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.176243
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.170701
CDK6 cyclin-dependent kinase 6 0.17066
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.170534
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.170362
TYRO3 TYRO3 protein tyrosine kinase 0.170318
WWOX WW domain containing oxidoreductase 0.169123
WIF1 WNT inhibitory factor 1 0.16833
BAD BCL2-associated agonist of cell death 0.1679