large cell carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A carcinoma that is composed of large, monotonous rounded or overtly polygonal-shaped cells with abundant cytoplasm. (Human Disease Ontology, DOID_4552)
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Genes

127 genes co-occuring with the disease large cell carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ENO2 enolase 2 (gamma, neuronal) 1.27911
NAPSA napsin A aspartic peptidase 1.17937
GLE1 GLE1 RNA export mediator 1.14687
NKX2-1 NK2 homeobox 1 1.11099
CHGA chromogranin A 1.10384
SYP synaptophysin 1.08118
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.03282
TP53 tumor protein p53 1.00837
KRT7 keratin 7, type II 0.96918
DSC2 desmocollin 2 0.95745
IGSF3 immunoglobulin superfamily, member 3 0.928346
EGFR epidermal growth factor receptor 0.923387
GRP gastrin-releasing peptide 0.888438
DSC3 desmocollin 3 0.850764
MRPS22 mitochondrial ribosomal protein S22 0.842163
KRAS Kirsten rat sarcoma viral oncogene homolog 0.838066
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.823308
CNN1 calponin 1, basic, smooth muscle 0.822897
EIF3A eukaryotic translation initiation factor 3, subunit A 0.815924
HRAS Harvey rat sarcoma viral oncogene homolog 0.780251
KRT5 keratin 5, type II 0.735838
KRT20 keratin 20, type I 0.730571
KRT19 keratin 19, type I 0.718846
RNF7 ring finger protein 7 0.718443
ASCL1 achaete-scute family bHLH transcription factor 1 0.705949
ACTN4 actinin, alpha 4 0.690293
NOP2 NOP2 nucleolar protein 0.688692
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.672324
PRB2 proline-rich protein BstNI subfamily 2 0.669936
PASK PAS domain containing serine/threonine kinase 0.637102
PCSK9 proprotein convertase subtilisin/kexin type 9 0.62728
PCSK7 proprotein convertase subtilisin/kexin type 7 0.61866
TAGLN transgelin 0.60264
NCAM1 neural cell adhesion molecule 1 0.596792
MPLKIP M-phase specific PLK1 interacting protein 0.587444
YARS tyrosyl-tRNA synthetase 0.582773
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.581217
ASPH aspartate beta-hydroxylase 0.568386
DACT3 dishevelled-binding antagonist of beta-catenin 3 0.564889
BIRC7 baculoviral IAP repeat containing 7 0.564112
CDKN2A cyclin-dependent kinase inhibitor 2A 0.553627
ERBB2 erb-b2 receptor tyrosine kinase 2 0.536957
CDX2 caudal type homeobox 2 0.519961
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.516494
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 0.51611
ALK anaplastic lymphoma receptor tyrosine kinase 0.503058
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.499614
CD109 CD109 molecule 0.487788
PCNA proliferating cell nuclear antigen 0.483985
CSH2 chorionic somatomammotropin hormone 2 0.479047
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.469954
CD44 CD44 molecule (Indian blood group) 0.469576
CTHRC1 collagen triple helix repeat containing 1 0.468819
AFP alpha-fetoprotein 0.457109
TKTL1 transketolase-like 1 0.448064
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.444676
XAGE1E X antigen family, member 1E 0.443923
RAB25 RAB25, member RAS oncogene family 0.438658
MALL mal, T-cell differentiation protein-like 0.434899
XAGE1B X antigen family, member 1B 0.43227
FXR1 fragile X mental retardation, autosomal homolog 1 0.429266
CALCA calcitonin-related polypeptide alpha 0.428891
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.425514
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.42214
TCEA1 transcription elongation factor A (SII), 1 0.419517
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.413153
BID BH3 interacting domain death agonist 0.389281
EEF2 eukaryotic translation elongation factor 2 0.375179
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.374438
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.364824
STX8 syntaxin 8 0.360395
PABPC1 poly(A) binding protein, cytoplasmic 1 0.35082
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.349349
EPHA7 EPH receptor A7 0.346409
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.337975
IGBP1 immunoglobulin (CD79A) binding protein 1 0.337242
ERCC1 excision repair cross-complementation group 1 0.335778
LGALS7 lectin, galactoside-binding, soluble, 7 0.329565
GCLM glutamate-cysteine ligase, modifier subunit 0.328105
PLAU plasminogen activator, urokinase 0.32373
MUC6 mucin 6, oligomeric mucus/gel-forming 0.319726
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.315003
EDN2 endothelin 2 0.305948
GREM1 gremlin 1, DAN family BMP antagonist 0.292257
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.285444
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.280796
MYOT myotilin 0.280439
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.270819
LDHA lactate dehydrogenase A 0.270819
CDX1 caudal type homeobox 1 0.268332
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.265494
STK11 serine/threonine kinase 11 0.261952
MCPH1 microcephalin 1 0.255946
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.253831
CTSH cathepsin H 0.252422
B3GAT1 beta-1,3-glucuronyltransferase 1 0.251015
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.248554
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.242595
PDGFA platelet-derived growth factor alpha polypeptide 0.231795
IVL involucrin 0.231102
GSTM1 glutathione S-transferase mu 1 0.226262
FLNB filamin B, beta 0.225917
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.217012
AKAP13 A kinase (PRKA) anchor protein 13 0.216672
STMN1 stathmin 1 0.216672
GFI1 growth factor independent 1 transcription repressor 0.216672
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.214297
STC1 stanniocalcin 1 0.213283
TIAM1 T-cell lymphoma invasion and metastasis 1 0.207245
CD6 CD6 molecule 0.206248
MMP2 matrix metallopeptidase 2 0.200331
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 0.196139
PDYN prodynorphin 0.195501
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.189551
LAP3 leucine aminopeptidase 3 0.187113
NSF N-ethylmaleimide-sensitive factor 0.186811
HLA-A major histocompatibility complex, class I, A 0.185612
BCL2 B-cell CLL/lymphoma 2 0.184424
AMY2A amylase, alpha 2A (pancreatic) 0.182086
GSTP1 glutathione S-transferase pi 1 0.178126
KRT8 keratin 8, type II 0.178126
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.176215
CKB creatine kinase, brain 0.175947
IL6 interleukin 6 0.165435
CD8B CD8b molecule 0.163317
FOXG1 forkhead box G1 0.158605
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.158434