lansoprazole-2967 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the lansoprazole-2967 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP13A2 ATPase type 13A2
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
C16ORF58 chromosome 16 open reading frame 58
C6ORF106 chromosome 6 open reading frame 106
CA8 carbonic anhydrase VIII
CAMKMT calmodulin-lysine N-methyltransferase
CAPN10 calpain 10
CCNK cyclin K
CCSER2 coiled-coil serine-rich protein 2
CEP41 centrosomal protein 41kDa
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CREM cAMP responsive element modulator
CTIF CBP80/20-dependent translation initiation factor
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYLD cylindromatosis (turban tumor syndrome)
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DBT dihydrolipoamide branched chain transacylase E2
DESI2 desumoylating isopeptidase 2
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DUS2 dihydrouridine synthase 2
EDAR ectodysplasin A receptor
EPHB2 EPH receptor B2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPN1 epsin 1
FAM120C family with sequence similarity 120C
FAM3A family with sequence similarity 3, member A
FASTK Fas-activated serine/threonine kinase
FCAR Fc fragment of IgA receptor
FNTB farnesyltransferase, CAAX box, beta
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GK glycerol kinase
GLRX3 glutaredoxin 3
GPATCH3 G patch domain containing 3
GPRASP1 G protein-coupled receptor associated sorting protein 1
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HMGN5 high mobility group nucleosome binding domain 5
HSPG2 heparan sulfate proteoglycan 2
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KHSRP KH-type splicing regulatory protein
KIAA1109 KIAA1109
KIF5C kinesin family member 5C
LTB4R leukotriene B4 receptor
MAP2K7 mitogen-activated protein kinase kinase 7
MED31 mediator complex subunit 31
MID1 midline 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MON2 MON2 homolog (S. cerevisiae)
MR1 major histocompatibility complex, class I-related
MTMR12 myotubularin related protein 12
MZF1 myeloid zinc finger 1
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit
NECAB3 N-terminal EF-hand calcium binding protein 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NMT2 N-myristoyltransferase 2
NUP88 nucleoporin 88kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PGAP1 post-GPI attachment to proteins 1
POLG polymerase (DNA directed), gamma
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PYGB phosphorylase, glycogen; brain
RASAL2 RAS protein activator like 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM42 RNA binding motif protein 42
RPL13P5 ribosomal protein L13 pseudogene 5
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SDS serine dehydratase
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC35F5 solute carrier family 35, member F5
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SS18 synovial sarcoma translocation, chromosome 18
SSTR5 somatostatin receptor 5
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STK11 serine/threonine kinase 11
STX7 syntaxin 7
TBCD tubulin folding cofactor D
TBL1X transducin (beta)-like 1X-linked
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMEM120B transmembrane protein 120B
TRIM3 tripartite motif containing 3
UBTF upstream binding transcription factor, RNA polymerase I
VWA8 von Willebrand factor A domain containing 8
WWC1 WW and C2 domain containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADM adrenomedullin
ADORA3 adenosine A3 receptor
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
BAHD1 bromo adjacent homology domain containing 1
BNC2 basonuclin 2
CCDC71 coiled-coil domain containing 71
CD82 CD82 molecule
CD9 CD9 molecule
CEL carboxyl ester lipase
CFP complement factor properdin
CHMP1A charged multivesicular body protein 1A
CISH cytokine inducible SH2-containing protein
CRYL1 crystallin, lambda 1
CTAGE9 CTAGE family, member 9
CTSV cathepsin V
DENND1C DENN/MADD domain containing 1C
DGAT1 diacylglycerol O-acyltransferase 1
DGKE diacylglycerol kinase, epsilon 64kDa
DHRS3 dehydrogenase/reductase (SDR family) member 3
DHRS9 dehydrogenase/reductase (SDR family) member 9
DUSP2 dual specificity phosphatase 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ENO2 enolase 2 (gamma, neuronal)
FBXL7 F-box and leucine-rich repeat protein 7
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FOS FBJ murine osteosarcoma viral oncogene homolog
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GLCE glucuronic acid epimerase
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRAMD4 GRAM domain containing 4
GSTZ1 glutathione S-transferase zeta 1
HCAR3 hydroxycarboxylic acid receptor 3
HHLA3 HERV-H LTR-associating 3
HILPDA hypoxia inducible lipid droplet-associated
HIST1H2BN histone cluster 1, H2bn
HLA-DMA major histocompatibility complex, class II, DM alpha
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HP haptoglobin
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KLF2 Kruppel-like factor 2
KLHL26 kelch-like family member 26
LINS lines homolog (Drosophila)
LRRC20 leucine rich repeat containing 20
MAP1S microtubule-associated protein 1S
MAP6D1 MAP6 domain containing 1
MED9 mediator complex subunit 9
MITF microphthalmia-associated transcription factor
MMP2 matrix metallopeptidase 2
MVD mevalonate (diphospho) decarboxylase
NDE1 nudE neurodevelopment protein 1
NINJ1 ninjurin 1
NINJ2 ninjurin 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NT5E 5'-nucleotidase, ecto (CD73)
PDLIM1 PDZ and LIM domain 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PMFBP1 polyamine modulated factor 1 binding protein 1
POMZP3 POM121 and ZP3 fusion
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
QPCT glutaminyl-peptide cyclotransferase
QTRT1 queuine tRNA-ribosyltransferase 1
RAB13 RAB13, member RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS16 regulator of G-protein signaling 16
RGS2 regulator of G-protein signaling 2
S1PR4 sphingosine-1-phosphate receptor 4
SHPK sedoheptulokinase
SLC12A9 solute carrier family 12, member 9
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNX15 sorting nexin 15
SPP1 secreted phosphoprotein 1
SSBP3 single stranded DNA binding protein 3
STAT5A signal transducer and activator of transcription 5A
THEM6 thioesterase superfamily member 6
TM7SF2 transmembrane 7 superfamily member 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM254 transmembrane protein 254
TRABD TraB domain containing
TRAF1 TNF receptor-associated factor 1
TRIP10 thyroid hormone receptor interactor 10
TSPAN32 tetraspanin 32
VSIG4 V-set and immunoglobulin domain containing 4
WNT10B wingless-type MMTV integration site family, member 10B
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZC3H3 zinc finger CCCH-type containing 3
ZNF197 zinc finger protein 197
ZNF286A zinc finger protein 286A
ZNF32 zinc finger protein 32
ZNF506 zinc finger protein 506
ZNF665 zinc finger protein 665
ZNF862 zinc finger protein 862