langerhans-cell histiocytosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A histiocytosis that is characterized by clonal proliferation of Langerhans cells. (Human Disease Ontology, DOID_2571)
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Genes

118 genes co-occuring with the disease langerhans-cell histiocytosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CD207 CD207 molecule, langerin 1.87975
CD68 CD68 molecule 1.83002
CD1A CD1a molecule 1.80968
LYZ lysozyme 1.50491
DEAF1 DEAF1 transcription factor 1.47594
IFNE interferon, epsilon 1.37076
S100A9 S100 calcium binding protein A9 1.15198
CD163 CD163 molecule 1.04125
OAT ornithine aminotransferase 1.01723
HAVCR1 hepatitis A virus cellular receptor 1 1.01259
FSCN1 fascin actin-bundling protein 1 1.00161
AVP arginine vasopressin 1.00035
ARAF A-Raf proto-oncogene, serine/threonine kinase 0.997392
CD34 CD34 molecule 0.89623
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.874509
KIAA1549 KIAA1549 0.855677
COX6CP4 cytochrome c oxidase subunit VIc pseudogene 4 0.855677
CD1C CD1c molecule 0.855268
TARM1 T cell-interacting, activating receptor on myeloid cells 1 0.840525
WDR76 WD repeat domain 76 0.820437
FSCN3 fascin actin-bundling protein 3, testicular 0.80936
CD4 CD4 molecule 0.784755
FSCN2 fascin actin-bundling protein 2, retinal 0.78066
ACPP acid phosphatase, prostate 0.754527
FXYD5 FXYD domain containing ion transport regulator 5 0.749237
CD101 CD101 molecule 0.74436
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.723694
CCNB3 cyclin B3 0.722482
IGKC immunoglobulin kappa constant 0.710378
MAP2K1 mitogen-activated protein kinase kinase 1 0.687091
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.647348
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.635528
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.606152
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.604201
PTPRC protein tyrosine phosphatase, receptor type, C 0.513802
ITGAD integrin, alpha D 0.507657
STAB1 stabilin 1 0.484364
GSN gelsolin 0.484364
PHYH phytanoyl-CoA 2-hydroxylase 0.483224
TIMD4 T-cell immunoglobulin and mucin domain containing 4 0.465038
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.461639
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 0.457109
GHRH growth hormone releasing hormone 0.421016
CD83 CD83 molecule 0.415773
CD7 CD7 molecule 0.405678
TP53 tumor protein p53 0.403811
CRNN cornulin 0.398216
CD209 CD209 molecule 0.390769
ALPPL2 alkaline phosphatase, placental-like 2 0.390025
ALPP alkaline phosphatase, placental 0.389653
ALPL alkaline phosphatase, liver/bone/kidney 0.389281
PCNA proliferating cell nuclear antigen 0.385936
CCR7 chemokine (C-C motif) receptor 7 0.384822
HECA headcase homolog (Drosophila) 0.379626
ALYREF Aly/REF export factor 0.379256
STX11 syntaxin 11 0.368149
CTSE cathepsin E 0.35892
BCL2A1 BCL2-related protein A1 0.350452
DCK deoxycytidine kinase 0.347879
IL11 interleukin 11 0.342372
AVPR2 arginine vasopressin receptor 2 0.342006
CD1B CD1b molecule 0.341639
SEBOX SEBOX homeobox 0.33651
CCR6 chemokine (C-C motif) receptor 6 0.335412
ADRB1 adrenoceptor beta 1 0.335046
GPR83 G protein-coupled receptor 83 0.332487
TRH thyrotropin-releasing hormone 0.328469
LDHAL6B lactate dehydrogenase A-like 6B 0.326281
TMC6 transmembrane channel-like 6 0.325552
FOXP3 forkhead box P3 0.319363
AR androgen receptor 0.316819
ANXA3 annexin A3 0.309204
DUX4L8 double homeobox 4 like 8 0.299452
IL2RA interleukin 2 receptor, alpha 0.299092
LY75 lymphocyte antigen 75 0.298731
BCOR BCL6 corepressor 0.294413
CYS1 cystin 1 0.290462
CCL20 chemokine (C-C motif) ligand 20 0.282225
THEM4 thioesterase superfamily member 4 0.279367
LDHAL6A lactate dehydrogenase A-like 6A 0.271174
ENO2 enolase 2 (gamma, neuronal) 0.270819
MMP12 matrix metallopeptidase 12 0.26514
UNC13D unc-13 homolog D (C. elegans) 0.263014
DUX4L6 double homeobox 4 like 6 0.262306
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.253831
CCL1 chemokine (C-C motif) ligand 1 0.25207
POMC proopiomelanocortin 0.238054
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.238054
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.231102
CD5 CD5 molecule 0.22937
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.216672
CST4 cystatin S 0.212608
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 0.212271
LPP LIM domain containing preferred translocation partner in lipoma 0.210589
SIX3 SIX homeobox 3 0.207578
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.204593
TNF tumor necrosis factor 0.204263
CD80 CD80 molecule 0.202618
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.201635
CD40LG CD40 ligand 0.198709
CD86 CD86 molecule 0.198064
IFNA2 interferon, alpha 2 0.196779
IL10 interleukin 10 0.194548
DSPP dentin sialophosphoprotein 0.1936
S100B S100 calcium binding protein B 0.193285
JAG2 jagged 2 0.192344
CD40 CD40 molecule, TNF receptor superfamily member 5 0.192031
SPP1 secreted phosphoprotein 1 0.190786
JMJD6 jumonji domain containing 6 0.189551
POU5F1 POU class 5 homeobox 1 0.177576
UROS uroporphyrinogen III synthase 0.177301
SP100 SP100 nuclear antigen 0.176215
MKI67 marker of proliferation Ki-67 0.168617
CD38 CD38 molecule 0.167452
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.166319
LDHC lactate dehydrogenase C 0.165435
HBA1 hemoglobin, alpha 1 0.165435
RARA retinoic acid receptor, alpha 0.161139