lanatoside C-3771 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the lanatoside C-3771 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADM adrenomedullin
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANGPTL4 angiopoietin-like 4
ARC activity-regulated cytoskeleton-associated protein
ARL14 ADP-ribosylation factor-like 14
ATF3 activating transcription factor 3
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
BMP2 bone morphogenetic protein 2
BTG2 BTG family, member 2
CCNL1 cyclin L1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2AIP CDKN2A interacting protein
CLCF1 cardiotrophin-like cytokine factor 1
CLDN1 claudin 1
CLK1 CDC-like kinase 1
CREB5 cAMP responsive element binding protein 5
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DLX2 distal-less homeobox 2
DUSP1 dual specificity phosphatase 1
EDN1 endothelin 1
EFNB2 ephrin-B2
EGR1 early growth response 1
EGR3 early growth response 3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FAM46C family with sequence similarity 46, member C
FAM53C family with sequence similarity 53, member C
FLCN folliculin
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL2 FOS-like antigen 2
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
GPR20 G protein-coupled receptor 20
GRB7 growth factor receptor-bound protein 7
HBEGF heparin-binding EGF-like growth factor
HIST1H1T histone cluster 1, H1t
HIST1H2AE histone cluster 1, H2ae
HIST1H2BG histone cluster 1, H2bg
HIST1H4H histone cluster 1, H4h
HIST2H2BE histone cluster 2, H2be
HIST3H2A histone cluster 3, H2a
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL11 interleukin 11
IL1RL1 interleukin 1 receptor-like 1
IL6 interleukin 6
IP6K2 inositol hexakisphosphate kinase 2
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KDM5B lysine (K)-specific demethylase 5B
KLF4 Kruppel-like factor 4 (gut)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MYLIP myosin regulatory light chain interacting protein
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NMT2 N-myristoyltransferase 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NXF1 nuclear RNA export factor 1
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PELI1 pellino E3 ubiquitin protein ligase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSPC1 paraspeckle component 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RGS16 regulator of G-protein signaling 16
RHOB ras homolog family member B
RND1 Rho family GTPase 1
RPS28 ribosomal protein S28
RSRC2 arginine/serine-rich coiled-coil 2
RSRP1 arginine/serine-rich protein 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SFPQ splicing factor proline/glutamine-rich
SGK1 serum/glucocorticoid regulated kinase 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNAI1 snail family zinc finger 1
SRSF5 serine/arginine-rich splicing factor 5
STK17B serine/threonine kinase 17b
TEX14 testis expressed 14
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOB2 transducer of ERBB2, 2
TPP1 tripeptidyl peptidase I
TRA2A transformer 2 alpha homolog (Drosophila)
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ZFP36 ZFP36 ring finger protein
ZNF335 zinc finger protein 335

decreased expression

Symbol Name
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ASAP1-IT1 ASAP1 intronic transcript 1
ASB13 ankyrin repeat and SOCS box containing 13
C11ORF63 chromosome 11 open reading frame 63
C14ORF169 chromosome 14 open reading frame 169
C16ORF59 chromosome 16 open reading frame 59
C2ORF68 chromosome 2 open reading frame 68
C7ORF49 chromosome 7 open reading frame 49
C8ORF60 chromosome 8 open reading frame 60
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBR3 carbonyl reductase 3
CBX8 chromobox homolog 8
CCDC51 coiled-coil domain containing 51
CDC7 cell division cycle 7
CDH7 cadherin 7, type 2
CFAP44 cilia and flagella associated protein 44
CLP1 cleavage and polyadenylation factor I subunit 1
CPED1 cadherin-like and PC-esterase domain containing 1
CUTC cutC copper transporter
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DET1 de-etiolated homolog 1 (Arabidopsis)
DNAAF2 dynein, axonemal, assembly factor 2
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
FADD Fas (TNFRSF6)-associated via death domain
FANCF Fanconi anemia, complementation group F
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GEMIN4 gem (nuclear organelle) associated protein 4
GEMIN6 gem (nuclear organelle) associated protein 6
GLS2 glutaminase 2 (liver, mitochondrial)
GOLGA5 golgin A5
GRAMD1C GRAM domain containing 1C
GSPT2 G1 to S phase transition 2
HMGA2 high mobility group AT-hook 2
HOXA1 homeobox A1
HOXC4 homeobox C4
HPS6 Hermansky-Pudlak syndrome 6
ICT1 immature colon carcinoma transcript 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IMPACT impact RWD domain protein
IRAK4 interleukin-1 receptor-associated kinase 4
JRKL JRK-like
KIAA1462 KIAA1462
KRCC1 lysine-rich coiled-coil 1
LHX6 LIM homeobox 6
LMNB1 lamin B1
LMO2 LIM domain only 2 (rhombotin-like 1)
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MANEA mannosidase, endo-alpha
MED7 mediator complex subunit 7
MMP9 matrix metallopeptidase 9
MXD3 MAX dimerization protein 3
NDP Norrie disease (pseudoglioma)
PALB2 partner and localizer of BRCA2
PARD6A par-6 family cell polarity regulator alpha
PLD2 phospholipase D2
POGK pogo transposable element with KRAB domain
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRR15L proline rich 15-like
PRR3 proline rich 3
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RFC4 replication factor C (activator 1) 4, 37kDa
RGS20 regulator of G-protein signaling 20
RHOBTB1 Rho-related BTB domain containing 1
RHOBTB2 Rho-related BTB domain containing 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF25 ring finger protein 25
RPL23AP32 ribosomal protein L23a pseudogene 32
RPUSD2 RNA pseudouridylate synthase domain containing 2
RUNX1-IT1 RUNX1 intronic transcript 1
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SCO2 SCO2 cytochrome c oxidase assembly protein
SEPHS2 selenophosphate synthetase 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TBCCD1 TBCC domain containing 1
TFB1M transcription factor B1, mitochondrial
THAP4 THAP domain containing 4
TRIM32 tripartite motif containing 32
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
ZBED8 zinc finger, BED-type containing 8
ZFP69B ZFP69 zinc finger protein B
ZNF205 zinc finger protein 205
ZNF232 zinc finger protein 232
ZNF239 zinc finger protein 239
ZNF248 zinc finger protein 248
ZNF365 zinc finger protein 365
ZNF696 zinc finger protein 696
ZNF74 zinc finger protein 74
ZNF862 zinc finger protein 862