lactobionic acid-4950 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the lactobionic acid-4950 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AK2 adenylate kinase 2
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANXA2P3 annexin A2 pseudogene 3
ARHGAP28 Rho GTPase activating protein 28
ARMC4 armadillo repeat containing 4
ATAT1 alpha tubulin acetyltransferase 1
BMP5 bone morphogenetic protein 5
CCL21 chemokine (C-C motif) ligand 21
CD58 CD58 molecule
CDH8 cadherin 8, type 2
CEP250 centrosomal protein 250kDa
CRMP1 collapsin response mediator protein 1
DUSP6 dual specificity phosphatase 6
EDA ectodysplasin A
EHBP1L1 EH domain binding protein 1-like 1
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ENOX2 ecto-NOX disulfide-thiol exchanger 2
FBXL8 F-box and leucine-rich repeat protein 8
FLJ11292
FMO5 flavin containing monooxygenase 5
FRAS1 Fraser extracellular matrix complex subunit 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GBP1 guanylate binding protein 1, interferon-inducible
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRPR gastrin-releasing peptide receptor
GSPT1 G1 to S phase transition 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HGFAC HGF activator
HMG20B high mobility group 20B
HOXD11 homeobox D11
IGHM immunoglobulin heavy constant mu
INO80D INO80 complex subunit D
IRF4 interferon regulatory factor 4
KCNIP1 Kv channel interacting protein 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA1109 KIAA1109
KIF1C kinesin family member 1C
KLHDC8A kelch domain containing 8A
KRT32 keratin 32, type I
LAMP3 lysosomal-associated membrane protein 3
LOC100131532 uncharacterized LOC100131532
LTBP2 latent transforming growth factor beta binding protein 2
MORC1 MORC family CW-type zinc finger 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
N4BP1 NEDD4 binding protein 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NEUROD1 neuronal differentiation 1
NOS1 nitric oxide synthase 1 (neuronal)
NTF3 neurotrophin 3
PARD3 par-3 family cell polarity regulator
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGR progesterone receptor
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POPDC3 popeye domain containing 3
PTRF polymerase I and transcript release factor
QPCTL glutaminyl-peptide cyclotransferase-like
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS12 regulator of G-protein signaling 12
RIMS2 regulating synaptic membrane exocytosis 2
RPLP2 ribosomal protein, large, P2
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RSU1 Ras suppressor protein 1
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
SAYSD1 SAYSVFN motif domain containing 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMC4 structural maintenance of chromosomes 4
SPHK2 sphingosine kinase 2
STATH statherin
TAS2R1 taste receptor, type 2, member 1
TBX6 T-box 6
TEP1 telomerase-associated protein 1
TLR5 toll-like receptor 5
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TPMT thiopurine S-methyltransferase
TRA2A transformer 2 alpha homolog (Drosophila)
TRD T cell receptor delta locus
TRIO trio Rho guanine nucleotide exchange factor
TRIP11 thyroid hormone receptor interactor 11
UBE2I ubiquitin-conjugating enzyme E2I
USP22 ubiquitin specific peptidase 22
VWA5A von Willebrand factor A domain containing 5A
WDR55 WD repeat domain 55
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB43 zinc finger and BTB domain containing 43
ZNF10 zinc finger protein 10
ZNF518A zinc finger protein 518A
ZNF589 zinc finger protein 589
ZNF609 zinc finger protein 609
ZNF711 zinc finger protein 711

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTL8 actin-like 8
ADCY6 adenylate cyclase 6
AHDC1 AT hook, DNA binding motif, containing 1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMT aminomethyltransferase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARHGAP10 Rho GTPase activating protein 10
ATG9A autophagy related 9A
C11ORF30 chromosome 11 open reading frame 30
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBY1 chibby homolog 1 (Drosophila)
CCDC132 coiled-coil domain containing 132
CDK3 cyclin-dependent kinase 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHKB choline kinase beta
CHMP7 charged multivesicular body protein 7
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CISH cytokine inducible SH2-containing protein
CLDN15 claudin 15
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
CNPY3 canopy FGF signaling regulator 3
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAF1 DEAF1 transcription factor
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM204A family with sequence similarity 204, member A
FAM63A family with sequence similarity 63, member A
FBXL15 F-box and leucine-rich repeat protein 15
FBXL6 F-box and leucine-rich repeat protein 6
FRK fyn-related Src family tyrosine kinase
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GALK1 galactokinase 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GDAP1 ganglioside induced differentiation associated protein 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT140 intraflagellar transport 140
IRAK4 interleukin-1 receptor-associated kinase 4
JUNB jun B proto-oncogene
LHX6 LIM homeobox 6
MFAP2 microfibrillar-associated protein 2
MOSPD3 motile sperm domain containing 3
MPI mannose phosphate isomerase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NT5DC3 5'-nucleotidase domain containing 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PEX26 peroxisomal biogenesis factor 26
PGP phosphoglycolate phosphatase
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PISD phosphatidylserine decarboxylase
PMCH pro-melanin-concentrating hormone
PRR7 proline rich 7 (synaptic)
PRSS16 protease, serine, 16 (thymus)
PTPRU protein tyrosine phosphatase, receptor type, U
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RANGRF RAN guanine nucleotide release factor
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RECQL4 RecQ protein-like 4
SCGB2A2 secretoglobin, family 2A, member 2
SIX1 SIX homeobox 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35F5 solute carrier family 35, member F5
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
STK16 serine/threonine kinase 16
STX1A syntaxin 1A (brain)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D17 TBC1 domain family, member 17
TCTA T-cell leukemia translocation altered
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM104 transmembrane protein 104
TRAPPC2 trafficking protein particle complex 2
TRIM21 tripartite motif containing 21
UPK3B uroplakin 3B
USP18 ubiquitin specific peptidase 18
VLDLR very low density lipoprotein receptor
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZMAT5 zinc finger, matrin-type 5
ZNF37BP zinc finger protein 37B, pseudogene
ZNF442 zinc finger protein 442
ZNF573 zinc finger protein 573