lactobionic acid-3246 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the lactobionic acid-3246 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AMPD1 adenosine monophosphate deaminase 1
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
APOLD1 apolipoprotein L domain containing 1
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BAZ2A bromodomain adjacent to zinc finger domain, 2A
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCNG2 cyclin G2
CDC25C cell division cycle 25C
CDC37L1 cell division cycle 37-like 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLEC11A C-type lectin domain family 11, member A
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COL1A1 collagen, type I, alpha 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DGCR2 DiGeorge syndrome critical region gene 2
DTNA dystrobrevin, alpha
ETAA1 Ewing tumor-associated antigen 1
FAS Fas cell surface death receptor
FBXO4 F-box protein 4
FCF1 FCF1 rRNA-processing protein
FGR FGR proto-oncogene, Src family tyrosine kinase
FN1 fibronectin 1
FOXN3 forkhead box N3
FSCN1 fascin actin-bundling protein 1
GM2A GM2 ganglioside activator
ICOSLG inducible T-cell co-stimulator ligand
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGFBP5 insulin-like growth factor binding protein 5
IQCG IQ motif containing G
KDM6B lysine (K)-specific demethylase 6B
KIAA0430 KIAA0430
KITLG KIT ligand
KMT2A lysine (K)-specific methyltransferase 2A
KRT83 keratin 83, type II
LEPROT leptin receptor overlapping transcript
LIME1 Lck interacting transmembrane adaptor 1
LZTR1 leucine-zipper-like transcription regulator 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFAP3 microfibrillar-associated protein 3
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MR1 major histocompatibility complex, class I-related
MSH3 mutS homolog 3
MYO1E myosin IE
NFIB nuclear factor I/B
NOP16 NOP16 nucleolar protein
NPY2R neuropeptide Y receptor Y2
NRG1 neuregulin 1
ORC5 origin recognition complex, subunit 5
PARD6B par-6 family cell polarity regulator beta
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHB3 protocadherin beta 3
PHC3 polyhomeotic homolog 3 (Drosophila)
PHTF2 putative homeodomain transcription factor 2
PLSCR4 phospholipid scramblase 4
PRKCH protein kinase C, eta
PRKCI protein kinase C, iota
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RGS20 regulator of G-protein signaling 20
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF39 ring finger protein 39
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RXRB retinoid X receptor, beta
SCAMP1 secretory carrier membrane protein 1
SCAND2P SCAN domain containing 2 pseudogene
SIM2 single-minded family bHLH transcription factor 2
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC35E2 solute carrier family 35, member E2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SSPN sarcospan
STC1 stanniocalcin 1
STK16 serine/threonine kinase 16
STON1 stonin 1
SUGP1 SURP and G patch domain containing 1
SYNJ1 synaptojanin 1
TADA2A transcriptional adaptor 2A
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAOK2 TAO kinase 2
TCP11L1 t-complex 11, testis-specific-like 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TLK1 tousled-like kinase 1
TMEM242 transmembrane protein 242
TOR1AIP1 torsin A interacting protein 1
TTC33 tetratricopeptide repeat domain 33
TXNIP thioredoxin interacting protein
UTRN utrophin
VWA5A von Willebrand factor A domain containing 5A
WDFY3 WD repeat and FYVE domain containing 3
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YPEL1 yippee-like 1 (Drosophila)
ZBTB1 zinc finger and BTB domain containing 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF226 zinc finger protein 226
ZNF34 zinc finger protein 34
ZNF365 zinc finger protein 365
ZNF444 zinc finger protein 444

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACTL8 actin-like 8
ADGRG2 adhesion G protein-coupled receptor G2
AES amino-terminal enhancer of split
APLP1 amyloid beta (A4) precursor-like protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC4 armadillo repeat containing 4
ATG9A autophagy related 9A
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AXIN1 axin 1
BBC3 BCL2 binding component 3
CCDC69 coiled-coil domain containing 69
CCNO cyclin O
CIC capicua transcriptional repressor
CNN2 calponin 2
CSF1R colony stimulating factor 1 receptor
CSTA cystatin A (stefin A)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAF1 DEAF1 transcription factor
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNM1 dynamin 1
DUSP8 dual specificity phosphatase 8
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHA2 EPH receptor A2
EXD3 exonuclease 3'-5' domain containing 3
FAM131A family with sequence similarity 131, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FCHO1 FCH domain only 1
FOSL1 FOS-like antigen 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GADD45G growth arrest and DNA-damage-inducible, gamma
GALT galactose-1-phosphate uridylyltransferase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GMIP GEM interacting protein
GSTCD glutathione S-transferase, C-terminal domain containing
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GTPBP2 GTP binding protein 2
HDAC11 histone deacetylase 11
HIRA histone cell cycle regulator
HIST1H2BJ histone cluster 1, H2bj
HPN hepsin
IL15RA interleukin 15 receptor, alpha
IL4R interleukin 4 receptor
IRAK4 interleukin-1 receptor-associated kinase 4
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KREMEN2 kringle containing transmembrane protein 2
LHX6 LIM homeobox 6
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LYPD1 LY6/PLAUR domain containing 1
MAP1S microtubule-associated protein 1S
MBTD1 mbt domain containing 1
MRPL44 mitochondrial ribosomal protein L44
NPTX1 neuronal pentraxin I
NXPH4 neurexophilin 4
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSMR oncostatin M receptor
OVOL1 ovo-like zinc finger 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PGP phosphoglycolate phosphatase
PMEL premelanosome protein
PODXL2 podocalyxin-like 2
POR P450 (cytochrome) oxidoreductase
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTK6 protein tyrosine kinase 6
RABL6 RAB, member RAS oncogene family-like 6
RASAL1 RAS protein activator like 1 (GAP1 like)
RHBDD3 rhomboid domain containing 3
RNF122 ring finger protein 122
RNF126 ring finger protein 126
RNF2 ring finger protein 2
RPAP1 RNA polymerase II associated protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SECTM1 secreted and transmembrane 1
SETD1A SET domain containing 1A
SFXN1 sideroflexin 1
SLC12A8 solute carrier family 12, member 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SNAI2 snail family zinc finger 2
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK25 serine/threonine kinase 25
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM7SF2 transmembrane 7 superfamily member 2
TMEM209 transmembrane protein 209
TNRC6B trinucleotide repeat containing 6B
TRAIP TRAF interacting protein
UBQLN4 ubiquilin 4
UNC93B1 unc-93 homolog B1 (C. elegans)
WLS wntless Wnt ligand secretion mediator
ZBTB22 zinc finger and BTB domain containing 22
ZNF446 zinc finger protein 446
ZNF652 zinc finger protein 652