lactobionic acid-1309 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the lactobionic acid-1309 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACOX3 acyl-CoA oxidase 3, pristanoyl
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARF6 ADP-ribosylation factor 6
ASMTL acetylserotonin O-methyltransferase-like
ASTE1 asteroid homolog 1 (Drosophila)
ATP13A2 ATPase type 13A2
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
AURKA aurora kinase A
AZU1 azurocidin 1
BACE1 beta-site APP-cleaving enzyme 1
BAMBI BMP and activin membrane-bound inhibitor
BCR breakpoint cluster region
C16ORF59 chromosome 16 open reading frame 59
C17ORF53 chromosome 17 open reading frame 53
CCDC106 coiled-coil domain containing 106
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CHD4 chromodomain helicase DNA binding protein 4
CRTC1 CREB regulated transcription coactivator 1
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
EML3 echinoderm microtubule associated protein like 3
EVI5 ecotropic viral integration site 5
GCDH glutaryl-CoA dehydrogenase
GPR19 G protein-coupled receptor 19
GRIK5 glutamate receptor, ionotropic, kainate 5
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIPK2 homeodomain interacting protein kinase 2
HPS1 Hermansky-Pudlak syndrome 1
HSPA1L heat shock 70kDa protein 1-like
ICK intestinal cell (MAK-like) kinase
ICOSLG inducible T-cell co-stimulator ligand
IGL immunoglobulin lambda locus
IZUMO4 IZUMO family member 4
KAT6B K(lysine) acetyltransferase 6B
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD2 potassium channel tetramerization domain containing 2
KHSRP KH-type splicing regulatory protein
KIAA1107 KIAA1107
LMF2 lipase maturation factor 2
LTB4R leukotriene B4 receptor
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MECP2 methyl CpG binding protein 2
METTL7A methyltransferase like 7A
MRPL57 mitochondrial ribosomal protein L57
MZT2B mitotic spindle organizing protein 2B
NCAPH2 non-SMC condensin II complex, subunit H2
NEK9 NIMA-related kinase 9
NLRP1 NLR family, pyrin domain containing 1
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCGF2 polycomb group ring finger 2
PCGF3 polycomb group ring finger 3
PDCD2 programmed cell death 2
PEX6 peroxisomal biogenesis factor 6
PLCD1 phospholipase C, delta 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRR4 proline rich 4 (lacrimal)
RABGAP1 RAB GTPase activating protein 1
RPL10 ribosomal protein L10
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAFB2 scaffold attachment factor B2
SBNO1 strawberry notch homolog 1 (Drosophila)
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SERGEF secretion regulating guanine nucleotide exchange factor
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SIN3B SIN3 transcription regulator family member B
SIRT3 sirtuin 3
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SMOX spermine oxidase
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX2 sorting nexin 2
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUGP1 SURP and G patch domain containing 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAGLN transgelin
TCF4 transcription factor 4
TEX261 testis expressed 261
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
USP34 ubiquitin specific peptidase 34
WDR61 WD repeat domain 61
WDTC1 WD and tetratricopeptide repeats 1
YY1 YY1 transcription factor
ZBTB20 zinc finger and BTB domain containing 20
ZFHX2 zinc finger homeobox 2
ZNF250 zinc finger protein 250

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACOT13 acyl-CoA thioesterase 13
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADGRE2 adhesion G protein-coupled receptor E2
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARMC6 armadillo repeat containing 6
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASB6 ankyrin repeat and SOCS box containing 6
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTBD18 BTB (POZ) domain containing 18
CCS copper chaperone for superoxide dismutase
CECR1 cat eye syndrome chromosome region, candidate 1
CFL1 cofilin 1 (non-muscle)
CISH cytokine inducible SH2-containing protein
CLCN6 chloride channel, voltage-sensitive 6
COL9A2 collagen, type IX, alpha 2
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DOLK dolichol kinase
ECI2 enoyl-CoA delta isomerase 2
ETAA1 Ewing tumor-associated antigen 1
FAM160B2 family with sequence similarity 160, member B2
FAM50B family with sequence similarity 50, member B
FAM63A family with sequence similarity 63, member A
FLCN folliculin
GLTSCR1 glioma tumor suppressor candidate region gene 1
GRAMD1B GRAM domain containing 1B
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H2BH histone cluster 1, H2bh
HIST1H2BI histone cluster 1, H2bi
HMGB3P1 high mobility group box 3 pseudogene 1
HS1BP3 HCLS1 binding protein 3
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INF2 inverted formin, FH2 and WH2 domain containing
KIF20A kinesin family member 20A
LIG4 ligase IV, DNA, ATP-dependent
LIMD2 LIM domain containing 2
LMAN1 lectin, mannose-binding, 1
LOC157562 uncharacterized LOC157562
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRK1 leucine-rich repeat kinase 1
MED9 mediator complex subunit 9
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MIR22HG MIR22 host gene
MTERF1 mitochondrial transcription termination factor 1
MYO1E myosin IE
NARFL nuclear prelamin A recognition factor-like
NIPSNAP3B nipsnap homolog 3B (C. elegans)
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHACTR1 phosphatase and actin regulator 1
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLS1 plastin 1
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
RAB17 RAB17, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RARS arginyl-tRNA synthetase
RFPL1S RFPL1 antisense RNA 1
RNF121 ring finger protein 121
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
S1PR4 sphingosine-1-phosphate receptor 4
SCYL2 SCY1-like 2 (S. cerevisiae)
SERINC5 serine incorporator 5
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC25A40 solute carrier family 25, member 40
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNHG20 small nucleolar RNA host gene 20
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN2 tectonic family member 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THEM6 thioesterase superfamily member 6
THRAP3 thyroid hormone receptor associated protein 3
TMEM242 transmembrane protein 242
TMEM53 transmembrane protein 53
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSPAN32 tetraspanin 32
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
TXLNG taxilin gamma
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBL4A ubiquitin-like 4A
VASH1 vasohibin 1
VSIG4 V-set and immunoglobulin domain containing 4
WDR91 WD repeat domain 91
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC4H2 zinc finger, C4H2 domain containing
ZMYM1 zinc finger, MYM-type 1
ZNF232 zinc finger protein 232
ZNF253 zinc finger protein 253
ZNF324 zinc finger protein 324
ZNF552 zinc finger protein 552
ZNF747 zinc finger protein 747