kidney failure Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A kidney disease characterized by the failure of the kidneys to adequately filter waste products from the blood. (Human Disease Ontology, DOID_1074)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003606
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Genes

41 gene mutations causing the kidney failure phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACTN4 actinin, alpha 4
AGXT alanine-glyoxylate aminotransferase
APRT adenine phosphoribosyltransferase
AQP11 aquaporin 11
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
BCL2 B-cell CLL/lymphoma 2
BICC1 BicC family RNA binding protein 1
CCNI cyclin I
CD151 CD151 molecule (Raph blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A4 collagen, type IV, alpha 4
DNASE1 deoxyribonuclease I
FAS Fas cell surface death receptor
GLIS2 GLIS family zinc finger 2
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GRHPR glyoxylate reductase/hydroxypyruvate reductase
HMOX1 heme oxygenase 1
INVS inversin
LAMA5 laminin, alpha 5
LAMC1 laminin, gamma 1 (formerly LAMB2)
MDK midkine (neurite growth-promoting factor 2)
MPV17 MpV17 mitochondrial inner membrane protein
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
PAX2 paired box 2
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
POU3F3 POU class 3 homeobox 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRC protein tyrosine phosphatase, receptor type, C
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
TAL1 T-cell acute lymphocytic leukemia 1
TNS1 tensin 1
TXNIP thioredoxin interacting protein
WNT4 wingless-type MMTV integration site family, member 4
WT1 Wilms tumor 1
WWTR1 WW domain containing transcription regulator 1
XDH xanthine dehydrogenase