khellin-2004 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the khellin-2004 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACPP acid phosphatase, prostate
ADAM15 ADAM metallopeptidase domain 15
AKAP13 A kinase (PRKA) anchor protein 13
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
APLP2 amyloid beta (A4) precursor-like protein 2
APOC4 apolipoprotein C-IV
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARR3 arrestin 3, retinal (X-arrestin)
BST1 bone marrow stromal cell antigen 1
C9ORF9 chromosome 9 open reading frame 9
CA7 carbonic anhydrase VII
CALB2 calbindin 2
CC2D1A coiled-coil and C2 domain containing 1A
CCDC94 coiled-coil domain containing 94
CD37 CD37 molecule
CD82 CD82 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHD3 chromodomain helicase DNA binding protein 3
CLSPN claspin
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DUSP2 dual specificity phosphatase 2
DUSP6 dual specificity phosphatase 6
EIF1 eukaryotic translation initiation factor 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERBB2IP erbb2 interacting protein
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FAM153A family with sequence similarity 153, member A
FBXO31 F-box protein 31
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGL1 fibrinogen-like 1
FNBP1 formin binding protein 1
FOXJ3 forkhead box J3
GK glycerol kinase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR12 G protein-coupled receptor 12
GRK5 G protein-coupled receptor kinase 5
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IL1RAP interleukin 1 receptor accessory protein
IL6ST interleukin 6 signal transducer
ILF3 interleukin enhancer binding factor 3, 90kDa
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD3 potassium channel tetramerization domain containing 3
KIF3B kinesin family member 3B
LENEP lens epithelial protein
LRRC37A2 leucine rich repeat containing 37, member A2
LUZP1 leucine zipper protein 1
MAGED2 melanoma antigen family D2
MAP2K7 mitogen-activated protein kinase kinase 7
MAST2 microtubule associated serine/threonine kinase 2
MBOAT2 membrane bound O-acyltransferase domain containing 2
MGAM maltase-glucoamylase
MID2 midline 2
MOB3B MOB kinase activator 3B
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
N4BP1 NEDD4 binding protein 1
NIP7 NIP7, nucleolar pre-rRNA processing protein
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUP214 nucleoporin 214kDa
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
PDE8A phosphodiesterase 8A
PECAM1 platelet/endothelial cell adhesion molecule 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PLEK2 pleckstrin 2
POR P450 (cytochrome) oxidoreductase
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PTBP3 polypyrimidine tract binding protein 3
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PVR poliovirus receptor
RABL6 RAB, member RAS oncogene family-like 6
RPS11 ribosomal protein S11
RYK receptor-like tyrosine kinase
SAG S-antigen; retina and pineal gland (arrestin)
SGSM3 small G protein signaling modulator 3
SIRPA signal-regulatory protein alpha
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC22A14 solute carrier family 22, member 14
SLC22A18 solute carrier family 22, member 18
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SPDEF SAM pointed domain containing ETS transcription factor
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBC1D29 TBC1 domain family, member 29
TDRD3 tudor domain containing 3
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TTLL5 tubulin tyrosine ligase-like family member 5
ZC3H7B zinc finger CCCH-type containing 7B
ZNF24 zinc finger protein 24
ZNF721 zinc finger protein 721

decreased expression

Symbol Name
ADM adrenomedullin
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASCC1 activating signal cointegrator 1 complex subunit 1
ASL argininosuccinate lyase
ATG4A autophagy related 4A, cysteine peptidase
BLMH bleomycin hydrolase
C11ORF68 chromosome 11 open reading frame 68
C16ORF62 chromosome 16 open reading frame 62
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD2AP CD2-associated protein
CD302 CD302 molecule
CDK9 cyclin-dependent kinase 9
CDT1 chromatin licensing and DNA replication factor 1
CEP72 centrosomal protein 72kDa
COG7 component of oligomeric golgi complex 7
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTSL cathepsin L
DAD1 defender against cell death 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND5A DENN/MADD domain containing 5A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIABLO diablo, IAP-binding mitochondrial protein
DPH2 DPH2 homolog (S. cerevisiae)
DUSP12 dual specificity phosphatase 12
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
FAM222B family with sequence similarity 222, member B
FAM63A family with sequence similarity 63, member A
FBXO46 F-box protein 46
GATAD2A GATA zinc finger domain containing 2A
GOLPH3L golgi phosphoprotein 3-like
GSR glutathione reductase
GTF2B general transcription factor IIB
H2BFS H2B histone family, member S (pseudogene)
HINFP histone H4 transcription factor
HIST1H1E histone cluster 1, H1e
HK1 hexokinase 1
IFNA17 interferon, alpha 17
IMPACT impact RWD domain protein
IP6K1 inositol hexakisphosphate kinase 1
ISG15 ISG15 ubiquitin-like modifier
ITFG1 integrin alpha FG-GAP repeat containing 1
KDM5C lysine (K)-specific demethylase 5C
KIZ kizuna centrosomal protein
KLHL21 kelch-like family member 21
KRI1 KRI1 homolog (S. cerevisiae)
LBR lamin B receptor
LIMD2 LIM domain containing 2
LMNB1 lamin B1
LPPR3 lipid phosphate phosphatase-related protein type 3
LXN latexin
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MECR mitochondrial trans-2-enoyl-CoA reductase
MFF mitochondrial fission factor
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MT1HL1 metallothionein 1H-like 1
NDE1 nudE neurodevelopment protein 1
NHEJ1 nonhomologous end-joining factor 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOL12 nucleolar protein 12
NOL6 nucleolar protein 6 (RNA-associated)
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OXSR1 oxidative stress responsive 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARG poly (ADP-ribose) glycohydrolase
PCSK7 proprotein convertase subtilisin/kexin type 7
PEMT phosphatidylethanolamine N-methyltransferase
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PKN1 protein kinase N1
PLAG1 pleiomorphic adenoma gene 1
PMVK phosphomevalonate kinase
PNRC1 proline-rich nuclear receptor coactivator 1
POGK pogo transposable element with KRAB domain
RAB4B RAB4B, member RAS oncogene family
RGCC regulator of cell cycle
RPUSD2 RNA pseudouridylate synthase domain containing 2
SECISBP2 SECIS binding protein 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETDB1 SET domain, bifurcated 1
SHPK sedoheptulokinase
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMYD5 SMYD family member 5
SNORA21 small nucleolar RNA, H/ACA box 21
SNX6 sorting nexin 6
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STRA13 stimulated by retinoic acid 13
SUN2 Sad1 and UNC84 domain containing 2
TCTN2 tectonic family member 2
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM104 transmembrane protein 104
TMEM14A transmembrane protein 14A
TNF tumor necrosis factor
UNC93B1 unc-93 homolog B1 (C. elegans)
VASP vasodilator-stimulated phosphoprotein
WNT10B wingless-type MMTV integration site family, member 10B
ZNF140 zinc finger protein 140
ZNF408 zinc finger protein 408