kaposi's sarcoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A connective tissue cancer that derives_from lymphatic endothelium, and derives_from spindle cells, results_in_formation_of vascular channels that fill with blood cells, has_material_basis_in Human herpesvirus 8 (HHV8). (Human Disease Ontology, DOID_8632)
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Genes

328 genes co-occuring with the disease kaposi's sarcoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
VIL1 villin 1 2.13921
CD4 CD4 molecule 2.12269
TAT tyrosine aminotransferase 1.84227
WARS tryptophanyl-tRNA synthetase 1.78308
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.52512
IL6 interleukin 6 1.51501
KCP kielin/chordin-like protein 1.48999
F8 coagulation factor VIII, procoagulant component 1.48121
FGF2 fibroblast growth factor 2 (basic) 1.43815
CD34 CD34 molecule 1.27824
IFNA1 interferon, alpha 1 1.2369
HBA1 hemoglobin, alpha 1 1.22605
HBA2 hemoglobin, alpha 2 1.20093
FAM120C family with sequence similarity 120C 1.18324
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.16093
GYPC glycophorin C (Gerbich blood group) 1.13712
IRF7 interferon regulatory factor 7 1.1312
IRF1 interferon regulatory factor 1 1.11099
MED12 mediator complex subunit 12 1.04924
IRF3 interferon regulatory factor 3 1.02988
EFNA2 ephrin-A2 1.00752
TP53 tumor protein p53 1.00414
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.975903
CCR8 chemokine (C-C motif) receptor 8 0.961634
SUMO3 small ubiquitin-like modifier 3 0.961216
PABPC1 poly(A) binding protein, cytoplasmic 1 0.952856
CHMP2A charged multivesicular body protein 2A 0.945354
IL2 interleukin 2 0.94369
SUMO2 small ubiquitin-like modifier 2 0.942027
ZNF426 zinc finger protein 426 0.928759
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.922149
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 0.917199
BRD2 bromodomain containing 2 0.912257
CARTPT CART prepropeptide 0.908553
VEGFA vascular endothelial growth factor A 0.89623
KDR kinase insert domain receptor 0.892538
NXF1 nuclear RNA export factor 1 0.887618
CTCF CCCTC-binding factor (zinc finger protein) 0.885979
FADD Fas (TNFRSF6)-associated via death domain 0.874509
IRF2 interferon regulatory factor 2 0.872053
NOTCH1 notch 1 0.855268
TNF tumor necrosis factor 0.854449
FLT4 fms-related tyrosine kinase 4 0.853221
IFNA2 interferon, alpha 2 0.847898
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.841753
LY6G6C lymphocyte antigen 6 complex, locus G6C 0.826178
PROX1 prospero homeobox 1 0.817565
CDK6 cyclin-dependent kinase 6 0.803616
OSM oncostatin M 0.793361
HLA-B major histocompatibility complex, class I, B 0.782298
ICAM1 intercellular adhesion molecule 1 0.772887
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.761047
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.759416
HIST2H2AC histone cluster 2, H2ac 0.750457
IRF4 interferon regulatory factor 4 0.75005
HIST2H2AA3 histone cluster 2, H2aa3 0.75005
HIST2H2AA4 histone cluster 2, H2aa4 0.75005
IL6R interleukin 6 receptor 0.748017
HLA-A major histocompatibility complex, class I, A 0.735433
FYTTD1 forty-two-three domain containing 1 0.724502
BRD4 bromodomain containing 4 0.705949
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.70434
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.703938
RAD21 RAD21 homolog (S. pombe) 0.702732
KRT77 keratin 77, type II 0.701124
JUN jun proto-oncogene 0.694301
FGF1 fibroblast growth factor 1 (acidic) 0.689893
CD19 CD19 molecule 0.686691
FGF4 fibroblast growth factor 4 0.685891
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 0.681096
DUSP8 dual specificity phosphatase 8 0.679898
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.675909
BST2 bone marrow stromal cell antigen 2 0.668345
EPHA2 EPH receptor A2 0.659611
IL1B interleukin 1, beta 0.657234
CXCL8 chemokine (C-X-C motif) ligand 8 0.643404
CABIN1 calcineurin binding protein 1 0.643404
RPL34 ribosomal protein L34 0.622967
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.613574
ZNF222 zinc finger protein 222 0.60225
STAT1 signal transducer and activator of transcription 1, 91kDa 0.60225
FGF5 fibroblast growth factor 5 0.60147
KLHL24 kelch-like family member 24 0.58433
IL4 interleukin 4 0.583552
ANXA4 annexin A4 0.580439
DIAPH2 diaphanous-related formin 2 0.575383
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 0.570329
MCM3 minichromosome maintenance complex component 3 0.568775
PDPN podoplanin 0.568386
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.566054
XBP1 X-box binding protein 1 0.565277
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.562169
VEGFC vascular endothelial growth factor C 0.555956
PFDN4 prefoldin subunit 4 0.550911
DHFR dihydrofolate reductase 0.547032
NFAM1 NFAT activating protein with ITAM motif 1 0.54393
CCL3 chemokine (C-C motif) ligand 3 0.541605
ERVW-1 endogenous retrovirus group W, member 1 0.53928
TRIM28 tripartite motif containing 28 0.535409
CENPF centromere protein F, 350/400kDa 0.528835
CUL5 cullin 5 0.524202
ATG3 autophagy related 3 0.522273
IL4R interleukin 4 receptor 0.51919
CCR3 chemokine (C-C motif) receptor 3 0.514956
BZW1 basic leucine zipper and W2 domains 1 0.513417
PXN paxillin 0.511112
XRN1 5'-3' exoribonuclease 1 0.507273
IFNA21 interferon, alpha 21 0.506507
EPHA1 EPH receptor A1 0.503824
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.502675
CXCR2 chemokine (C-X-C motif) receptor 2 0.499614
FN1 fibronectin 1 0.498849
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.496939
IFNB1 interferon, beta 1, fibroblast 0.495793
CXCL10 chemokine (C-X-C motif) ligand 10 0.494266
RAB34 RAB34, member RAS oncogene family 0.492359
STAB1 stabilin 1 0.487788
DUT deoxyuridine triphosphatase 0.487027
CDH5 cadherin 5, type 2 (vascular endothelium) 0.486646
IFNA17 interferon, alpha 17 0.484744
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.477909
DEK DEK proto-oncogene 0.476393
B2M beta-2-microglobulin 0.476393
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.476014
CD68 CD68 molecule 0.471846
PARK2 parkin RBR E3 ubiquitin protein ligase 0.468063
EEA1 early endosome antigen 1 0.465416
JAK1 Janus kinase 1 0.465038
VCAM1 vascular cell adhesion molecule 1 0.459751
LYN LYN proto-oncogene, Src family tyrosine kinase 0.457487
ACTG1 actin gamma 1 0.451078
PLAU plasminogen activator, urokinase 0.451078
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.449194
CIITA class II, major histocompatibility complex, transactivator 0.446558
CD86 CD86 molecule 0.446558
CDCA2 cell division cycle associated 2 0.446182
CCNO cyclin O 0.444676
GBP1 guanylate binding protein 1, interferon-inducible 0.441666
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.43941
ST7L suppression of tumorigenicity 7 like 0.431894
TIPIN TIMELESS interacting protein 0.430768
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 0.428516
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.42664
ANG angiogenin, ribonuclease, RNase A family, 5 0.424014
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.42364
KRT15 keratin 15, type I 0.423265
CARD17 caspase recruitment domain family, member 17 0.421016
TLE2 transducin-like enhancer of split 2 0.419517
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.419142
EPHA5 EPH receptor A5 0.417644
CREBBP CREB binding protein 0.415398
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.415398
VWF von Willebrand factor 0.41465
SECTM1 secreted and transmembrane 1 0.412779
CCL2 chemokine (C-C motif) ligand 2 0.412405
EMCN endomucin 0.409787
BCL6 B-cell CLL/lymphoma 6 0.407172
MMP2 matrix metallopeptidase 2 0.398962
DUSP5 dual specificity phosphatase 5 0.397843
PDLIM7 PDZ and LIM domain 7 (enigma) 0.393001
UNG uracil-DNA glycosylase 0.392257
DROSHA drosha, ribonuclease type III 0.391885
RECQL RecQ helicase-like 0.390769
SETD1A SET domain containing 1A 0.385193
SELE selectin E 0.385193
CREB1 cAMP responsive element binding protein 1 0.384079
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.380368
EPS15 epidermal growth factor receptor pathway substrate 15 0.377402
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.374809
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.372958
PPAN peter pan homolog (Drosophila) 0.372587
ERAS ES cell expressed Ras 0.372587
CD209 CD209 molecule 0.369258
CD200 CD200 molecule 0.368518
SLURP1 secreted LY6/PLAUR domain containing 1 0.365193
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 0.362239
DAXX death-domain associated protein 0.359289
RPA1 replication protein A1, 70kDa 0.359289
CD200R1 CD200 receptor 1 0.357814
SMC3 structural maintenance of chromosomes 3 0.356709
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 0.356709
IFI16 interferon, gamma-inducible protein 16 0.355972
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.351923
MED23 mediator complex subunit 23 0.348246
CD40 CD40 molecule, TNF receptor superfamily member 5 0.347144
LGALS4 lectin, galactoside-binding, soluble, 4 0.347144
SEBOX SEBOX homeobox 0.344941
ITSN2 intersectin 2 0.342739
EPHA3 EPH receptor A3 0.33944
CDK2 cyclin-dependent kinase 2 0.338341
TYMS thymidylate synthetase 0.337975
GSTA3 glutathione S-transferase alpha 3 0.337608
IL6ST interleukin 6 signal transducer 0.337608
BCLAF1 BCL2-associated transcription factor 1 0.337608
GSTA2 glutathione S-transferase alpha 2 0.336144
KLRF1 killer cell lectin-like receptor subfamily F, member 1 0.335778
PDGFB platelet-derived growth factor beta polypeptide 0.335046
GSTA4 glutathione S-transferase alpha 4 0.335046
BAX BCL2-associated X protein 0.335046
MED25 mediator complex subunit 25 0.334315
MED15 mediator complex subunit 15 0.331756
GSTA1 glutathione S-transferase alpha 1 0.329565
RNF31 ring finger protein 31 0.328469
EPHA7 EPH receptor A7 0.328469
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.320817
TRAF3 TNF receptor-associated factor 3 0.316819
IL13 interleukin 13 0.31464
KDM3A lysine (K)-specific demethylase 3A 0.313552
HDAC9 histone deacetylase 9 0.312827
VARS valyl-tRNA synthetase 0.312827
HLA-DMB major histocompatibility complex, class II, DM beta 0.309928
BCL2L1 BCL2-like 1 0.307033
CXCL3 chemokine (C-X-C motif) ligand 3 0.303781
HLA-E major histocompatibility complex, class I, E 0.299092
CLEC2B C-type lectin domain family 2, member B 0.298011
LARS leucyl-tRNA synthetase 0.296931
SLC35G5 solute carrier family 35, member G5 0.295132
ORAOV1 oral cancer overexpressed 1 0.294413
NUMA1 nuclear mitotic apparatus protein 1 0.289027
SH2D1A SH2 domain containing 1A 0.288668
MIR187 microRNA 187 0.28616
EFNA4 ephrin-A4 0.285444
BSX brain-specific homeobox 0.284371
SYK spleen tyrosine kinase 0.280796
SMAD5 SMAD family member 5 0.280439
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.276158
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.275445
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.274732
CD80 CD80 molecule 0.273308
B3GAT1 beta-1,3-glucuronyltransferase 1 0.272953
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.272953
ANXA2 annexin A2 0.272241
CISH cytokine inducible SH2-containing protein 0.269753
CD79A CD79a molecule, immunoglobulin-associated alpha 0.269398
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.267622
IPO7 importin 7 0.266558
BCL2 B-cell CLL/lymphoma 2 0.266203
KIAA0226 KIAA0226 0.265849
SPHK2 sphingosine kinase 2 0.265494
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.264785
KAT7 K(lysine) acetyltransferase 7 0.262306
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.262306
ALPPL2 alkaline phosphatase, placental-like 2 0.262306
ALPP alkaline phosphatase, placental 0.261952
PYGO2 pygopus family PHD finger 2 0.261952
H3F3A H3 histone, family 3A 0.261245
ALPL alkaline phosphatase, liver/bone/kidney 0.261245
H3F3B H3 histone, family 3B (H3.3B) 0.261245
MT3 metallothionein 3 0.260538
RNASEH2A ribonuclease H2, subunit A 0.260184
FOS FBJ murine osteosarcoma viral oncogene homolog 0.259124
AXIN1 axin 1 0.256652
ANGPT4 angiopoietin 4 0.254536
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.25207
ZHX2 zinc fingers and homeoboxes 2 0.24996
CCND1 cyclin D1 0.244345
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.244345
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.243995
YY1 YY1 transcription factor 0.243995
MAPK3 mitogen-activated protein kinase 3 0.242245
MICB MHC class I polypeptide-related sequence B 0.241895
PCNA proliferating cell nuclear antigen 0.241895
MECP2 methyl CpG binding protein 2 0.240847
BIRC5 baculoviral IAP repeat containing 5 0.240847
FLT1 fms-related tyrosine kinase 1 0.237009
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.23666
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.236312
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.235616
MAN1A1 mannosidase, alpha, class 1A, member 1 0.23492
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.23492
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.232489
RNF4 ring finger protein 4 0.231448
LPCAT2 lysophosphatidylcholine acyltransferase 2 0.229716
GLTSCR2 glioma tumor suppressor candidate region gene 2 0.22937
PML promyelocytic leukemia 0.227642
HOXB6 homeobox B6 0.223165
PTK2B protein tyrosine kinase 2 beta 0.222822
CAMLG calcium modulating ligand 0.222136
TICAM2 toll-like receptor adaptor molecule 2 0.217012
PCBP1 poly(rC) binding protein 1 0.212271
SRP72 signal recognition particle 72kDa 0.212271
SEPT7 septin 7 0.211934
SDC2 syndecan 2 0.205254
HCK HCK proto-oncogene, Src family tyrosine kinase 0.201308
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 0.200006
IFNLR1 interferon, lambda receptor 1 0.199356
CSF3 colony stimulating factor 3 (granulocyte) 0.198386
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.197099
FGFR2 fibroblast growth factor receptor 2 0.196779
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.19582
CNGB1 cyclic nucleotide gated channel beta 1 0.195183
RRM1 ribonucleotide reductase M1 0.192344
CDK7 cyclin-dependent kinase 7 0.191719
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.191097
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.190786
EPHB2 EPH receptor B2 0.190168
AKR1D1 aldo-keto reductase family 1, member D1 0.188326
EPHB4 EPH receptor B4 0.188326
EIF4E eukaryotic translation initiation factor 4E 0.187719
SCARB2 scavenger receptor class B, member 2 0.187415
CXCR1 chemokine (C-X-C motif) receptor 1 0.186811
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.185612
NELFCD negative elongation factor complex member C/D 0.183835
TGFB1 transforming growth factor, beta 1 0.183248
STAT2 signal transducer and activator of transcription 2, 113kDa 0.182086
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.180652
CDK4 cyclin-dependent kinase 4 0.177851
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.177576
THBS1 thrombospondin 1 0.177029
FGF6 fibroblast growth factor 6 0.176485
CD36 CD36 molecule (thrombospondin receptor) 0.175411
ANGPTL4 angiopoietin-like 4 0.174881
CIB1 calcium and integrin binding 1 (calmyrin) 0.174093
BRD3 bromodomain containing 3 0.171535
HES6 hes family bHLH transcription factor 6 0.171286
CD38 CD38 molecule 0.169571
NRN1 neuritin 1 0.16933
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 0.169091
PGF placental growth factor 0.166319
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.163523
LAMP1 lysosomal-associated membrane protein 1 0.162109
MIR98 microRNA 98 0.160203
NCR1 natural cytotoxicity triggering receptor 1 0.160203
SELL selectin L 0.159302
TLR3 toll-like receptor 3 0.159124
MMP9 matrix metallopeptidase 9 0.158951
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.158778
XCL1 chemokine (C motif) ligand 1 0.158266