kanamycin-4625 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the kanamycin-4625 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ALOXE3 arachidonate lipoxygenase 3
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
AOC2 amine oxidase, copper containing 2 (retina-specific)
ASPN asporin
ASTN2 astrotactin 2
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C21ORF2 chromosome 21 open reading frame 2
C5ORF42 chromosome 5 open reading frame 42
CAPN9 calpain 9
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFAP43 cilia and flagella associated protein 43
CORO2B coronin, actin binding protein, 2B
CPN2 carboxypeptidase N, polypeptide 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
CYSLTR1 cysteinyl leukotriene receptor 1
DRP2 dystrophin related protein 2
DYM dymeclin
EDA ectodysplasin A
EPYC epiphycan
ETV7 ets variant 7
F12 coagulation factor XII (Hageman factor)
FAM198B family with sequence similarity 198, member B
FASN fatty acid synthase
FDPS farnesyl diphosphate synthase
FMO3 flavin containing monooxygenase 3
FOXO4 forkhead box O4
FRMD8 FERM domain containing 8
FSHB follicle stimulating hormone, beta polypeptide
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GAST gastrin
GPM6A glycoprotein M6A
GPR22 G protein-coupled receptor 22
GREM1 gremlin 1, DAN family BMP antagonist
GUCA1B guanylate cyclase activator 1B (retina)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HOXB2 homeobox B2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICA1 islet cell autoantigen 1, 69kDa
IFNA8 interferon, alpha 8
IL37 interleukin 37
JPH3 junctophilin 3
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KYNU kynureninase
LARGE like-glycosyltransferase
LAX1 lymphocyte transmembrane adaptor 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MGC2889 uncharacterized protein MGC2889
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTCP1 mature T-cell proliferation 1
NCOA2 nuclear receptor coactivator 2
NIPAL2 NIPA-like domain containing 2
NR2F6 nuclear receptor subfamily 2, group F, member 6
PAX8 paired box 8
PBX2 pre-B-cell leukemia homeobox 2
PDE11A phosphodiesterase 11A
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PNPLA2 patatin-like phospholipase domain containing 2
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRKG1 protein kinase, cGMP-dependent, type I
PSG11 pregnancy specific beta-1-glycoprotein 11
PSG9 pregnancy specific beta-1-glycoprotein 9
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB11B RAB11B, member RAS oncogene family
RARG retinoic acid receptor, gamma
RPS4Y1 ribosomal protein S4, Y-linked 1
RRAGD Ras-related GTP binding D
SAPCD1 suppressor APC domain containing 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SENP7 SUMO1/sentrin specific peptidase 7
SEPP1 selenoprotein P, plasma, 1
SH2B1 SH2B adaptor protein 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC16A6 solute carrier family 16, member 6
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SND1-IT1 SND1 intronic transcript 1
SPHK2 sphingosine kinase 2
STS steroid sulfatase (microsomal), isozyme S
TAS2R9 taste receptor, type 2, member 9
TBXA2R thromboxane A2 receptor
THSD7A thrombospondin, type I, domain containing 7A
TMEM19 transmembrane protein 19
TRIM2 tripartite motif containing 2
TRIM31 tripartite motif containing 31
WNT2 wingless-type MMTV integration site family member 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF205 zinc finger protein 205
ZNF234 zinc finger protein 234

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABHD17B abhydrolase domain containing 17B
ADGRB2 adhesion G protein-coupled receptor B2
AFAP1 actin filament associated protein 1
AGO4 argonaute RISC catalytic component 4
ALS2CL ALS2 C-terminal like
AMT aminomethyltransferase
AP4M1 adaptor-related protein complex 4, mu 1 subunit
BIRC3 baculoviral IAP repeat containing 3
C11ORF30 chromosome 11 open reading frame 30
C1ORF105 chromosome 1 open reading frame 105
C5ORF45 chromosome 5 open reading frame 45
CAPN15 calpain 15
CARD9 caspase recruitment domain family, member 9
CISH cytokine inducible SH2-containing protein
COG4 component of oligomeric golgi complex 4
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTC1 CTS telomere maintenance complex component 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNM3 dynamin 3
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFCAB2 EF-hand calcium binding domain 2
ERO1LB ERO1-like beta (S. cerevisiae)
FAT4 FAT atypical cadherin 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMPD1 FERM and PDZ domain containing 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GCC1 GRIP and coiled-coil domain containing 1
GLS2 glutaminase 2 (liver, mitochondrial)
GMPR guanosine monophosphate reductase
GPR19 G protein-coupled receptor 19
HDAC7 histone deacetylase 7
HIST1H1T histone cluster 1, H1t
HIST1H2AL histone cluster 1, H2al
HIST1H3I histone cluster 1, H3i
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA1 homeobox A1
ICOS inducible T-cell co-stimulator
IFI6 interferon, alpha-inducible protein 6
IFT140 intraflagellar transport 140
KDM7A lysine (K)-specific demethylase 7A
KDM8 lysine (K)-specific demethylase 8
KIAA0513 KIAA0513
KRT8P12 keratin 8 pseudogene 12
LINC00597 long intergenic non-protein coding RNA 597
LINS lines homolog (Drosophila)
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LY6D lymphocyte antigen 6 complex, locus D
MBTPS2 membrane-bound transcription factor peptidase, site 2
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MMP2 matrix metallopeptidase 2
MOCS3 molybdenum cofactor synthesis 3
MRPL41 mitochondrial ribosomal protein L41
MT1M metallothionein 1M
MX1 MX dynamin-like GTPase 1
NMRK1 nicotinamide riboside kinase 1
ORC1 origin recognition complex, subunit 1
PAIP2B poly(A) binding protein interacting protein 2B
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCDH12 protocadherin 12
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAC8 placenta-specific 8
PLD2 phospholipase D2
PODXL2 podocalyxin-like 2
PRM2 protamine 2
PSORS1C1 psoriasis susceptibility 1 candidate 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB33B RAB33B, member RAS oncogene family
RASA2 RAS p21 protein activator 2
RUSC2 RUN and SH3 domain containing 2
SCAI suppressor of cancer cell invasion
SCG5 secretogranin V
SERTAD3 SERTA domain containing 3
SH2D4A SH2 domain containing 4A
SLC35F6 solute carrier family 35, member F6
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOX30 SRY (sex determining region Y)-box 30
SRD5A3 steroid 5 alpha-reductase 3
STAB2 stabilin 2
SYNGR3 synaptogyrin 3
TGFB3 transforming growth factor, beta 3
TMEM121 transmembrane protein 121
TRAPPC2 trafficking protein particle complex 2
TTLL7 tubulin tyrosine ligase-like family member 7
USB1 U6 snRNA biogenesis 1
USP19 ubiquitin specific peptidase 19
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
YY2 YY2 transcription factor
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF254 zinc finger protein 254
ZNF711 zinc finger protein 711
ZNF747 zinc finger protein 747
ZSCAN2 zinc finger and SCAN domain containing 2