isoxicam-7268 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the isoxicam-7268 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADK adenosine kinase
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKMY1 ankyrin repeat and MYND domain containing 1
ARMC9 armadillo repeat containing 9
ARRB2 arrestin, beta 2
ASIC1 acid sensing (proton gated) ion channel 1
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
BAX BCL2-associated X protein
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BTD biotinidase
BTN3A1 butyrophilin, subfamily 3, member A1
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CCNF cyclin F
CCNT2 cyclin T2
CEP112 centrosomal protein 112kDa
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COL6A1 collagen, type VI, alpha 1
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CSPP1 centrosome and spindle pole associated protein 1
CTNND2 catenin (cadherin-associated protein), delta 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DESI2 desumoylating isopeptidase 2
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
ERMAP erythroblast membrane-associated protein (Scianna blood group)
F11R F11 receptor
FRS3 fibroblast growth factor receptor substrate 3
FXR2 fragile X mental retardation, autosomal homolog 2
FZD7 frizzled class receptor 7
GLG1 golgi glycoprotein 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GOLGA1 golgin A1
GOLGA8A golgin A8 family, member A
GPER1 G protein-coupled estrogen receptor 1
HAUS6 HAUS augmin-like complex, subunit 6
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HN1L hematological and neurological expressed 1-like
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
IL1RAP interleukin 1 receptor accessory protein
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INTS6 integrator complex subunit 6
IRF2BP1 interferon regulatory factor 2 binding protein 1
JUNB jun B proto-oncogene
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0319L KIAA0319-like
KIAA1107 KIAA1107
KIDINS220 kinase D-interacting substrate, 220kDa
LOC644450 uncharacterized LOC644450
MAN1B1 mannosidase, alpha, class 1B, member 1
MAPK7 mitogen-activated protein kinase 7
MYO9B myosin IXB
NF2 neurofibromin 2 (merlin)
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PCF11 PCF11 cleavage and polyadenylation factor subunit
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PER3 period circadian clock 3
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLSCR4 phospholipid scramblase 4
POMT2 protein-O-mannosyltransferase 2
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PTK7 protein tyrosine kinase 7 (inactive)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RARA retinoic acid receptor, alpha
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF19B ring finger protein 19B
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPAIN RPA interacting protein
SCAMP1 secretory carrier membrane protein 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SH3BP2 SH3-domain binding protein 2
STBD1 starch binding domain 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAZ tafazzin
TDRKH tudor and KH domain containing
THOC5 THO complex 5
TMED7 transmembrane emp24 protein transport domain containing 7
TPK1 thiamin pyrophosphokinase 1
TRIM25 tripartite motif containing 25
TUBD1 tubulin, delta 1
TUBGCP2 tubulin, gamma complex associated protein 2
USP34 ubiquitin specific peptidase 34
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB10 zinc finger and BTB domain containing 10
ZHX3 zinc fingers and homeoboxes 3
ZNF280D zinc finger protein 280D
ZNF358 zinc finger protein 358
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ACADSB acyl-CoA dehydrogenase, short/branched chain
AFAP1 actin filament associated protein 1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ASB7 ankyrin repeat and SOCS box containing 7
AXIN1 axin 1
C11ORF80 chromosome 11 open reading frame 80
C16ORF59 chromosome 16 open reading frame 59
C1ORF115 chromosome 1 open reading frame 115
C4ORF19 chromosome 4 open reading frame 19
C8ORF60 chromosome 8 open reading frame 60
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC176 coiled-coil domain containing 176
CCNO cyclin O
CCNT1 cyclin T1
CDC45 cell division cycle 45
CDH3 cadherin 3, type 1, P-cadherin (placental)
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHKB choline kinase beta
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLSPN claspin
CNGB3 cyclic nucleotide gated channel beta 3
CTSF cathepsin F
DCLRE1A DNA cross-link repair 1A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DSPP dentin sialophosphoprotein
DTWD1 DTW domain containing 1
E4F1 E4F transcription factor 1
EDC3 enhancer of mRNA decapping 3
EHD3 EH-domain containing 3
EN1 engrailed homeobox 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERMP1 endoplasmic reticulum metallopeptidase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM114A2 family with sequence similarity 114, member A2
FAM53B family with sequence similarity 53, member B
FAM86C1 family with sequence similarity 86, member C1
FBXL2 F-box and leucine-rich repeat protein 2
FBXO46 F-box protein 46
GALNS galactosamine (N-acetyl)-6-sulfatase
GDAP1 ganglioside induced differentiation associated protein 1
GPATCH3 G patch domain containing 3
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC5 histone deacetylase 5
HLX H2.0-like homeobox
HOXA4 homeobox A4
HOXC8 homeobox C8
IFT81 intraflagellar transport 81
IGFLR1 IGF-like family receptor 1
INF2 inverted formin, FH2 and WH2 domain containing
KIAA1462 KIAA1462
KIRREL kin of IRRE like (Drosophila)
KISS1 KiSS-1 metastasis-suppressor
KLK5 kallikrein-related peptidase 5
LSR lipolysis stimulated lipoprotein receptor
MACROD1 MACRO domain containing 1
MBL1P mannose-binding lectin (protein A) 1, pseudogene
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MED15 mediator complex subunit 15
MED22 mediator complex subunit 22
MMP1 matrix metallopeptidase 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTMR12 myotubularin related protein 12
MTRF1 mitochondrial translational release factor 1
MXRA8 matrix-remodelling associated 8
NEIL3 nei endonuclease VIII-like 3 (E. coli)
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PARD6A par-6 family cell polarity regulator alpha
PDE8B phosphodiesterase 8B
PLD3 phospholipase D family, member 3
RAB20 RAB20, member RAS oncogene family
REPS2 RALBP1 associated Eps domain containing 2
RNF25 ring finger protein 25
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A40 solute carrier family 25, member 40
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D17 TBC1 domain family, member 17
TMCC2 transmembrane and coiled-coil domain family 2
TMEM121 transmembrane protein 121
TMEM183A transmembrane protein 183A
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNS2 tensin 2
TRABD TraB domain containing
TRIM21 tripartite motif containing 21
TUBA3D tubulin, alpha 3d
USP27X ubiquitin specific peptidase 27, X-linked
ZNF16 zinc finger protein 16
ZNF222 zinc finger protein 222
ZNF415 zinc finger protein 415
ZNF574 zinc finger protein 574
ZNF813 zinc finger protein 813