isopropamide iodide-7133 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the isopropamide iodide-7133 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACSM3 acyl-CoA synthetase medium-chain family member 3
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ARL15 ADP-ribosylation factor-like 15
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP5SL ATP5S-like
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
AUH AU RNA binding protein/enoyl-CoA hydratase
BTN3A1 butyrophilin, subfamily 3, member A1
C15ORF39 chromosome 15 open reading frame 39
C2ORF68 chromosome 2 open reading frame 68
C4ORF19 chromosome 4 open reading frame 19
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC7 coiled-coil domain containing 7
CCDC85C coiled-coil domain containing 85C
CCS copper chaperone for superoxide dismutase
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDYL chromodomain protein, Y-like
CLCN4 chloride channel, voltage-sensitive 4
CPNE7 copine VII
CREB3L1 cAMP responsive element binding protein 3-like 1
CREBZF CREB/ATF bZIP transcription factor
CXCL3 chemokine (C-X-C motif) ligand 3
CXORF56 chromosome X open reading frame 56
DDN dendrin
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DMTN dematin actin binding protein
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOCK10 dedicator of cytokinesis 10
EMC3 ER membrane protein complex subunit 3
EN2 engrailed homeobox 2
FBXL2 F-box and leucine-rich repeat protein 2
FDX1 ferredoxin 1
GFER growth factor, augmenter of liver regeneration
GSAP gamma-secretase activating protein
HLX H2.0-like homeobox
HOMER3 homer scaffolding protein 3
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IL11RA interleukin 11 receptor, alpha
IL6ST interleukin 6 signal transducer
JAK2 Janus kinase 2
KLHL28 kelch-like family member 28
KRIT1 KRIT1, ankyrin repeat containing
LIMK2 LIM domain kinase 2
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAPK14 mitogen-activated protein kinase 14
MCM3AP minichromosome maintenance complex component 3 associated protein
MVK mevalonate kinase
NCKIPSD NCK interacting protein with SH3 domain
NCOA2 nuclear receptor coactivator 2
NSD1 nuclear receptor binding SET domain protein 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
PARVA parvin, alpha
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLAC1 placenta-specific 1
PLCD1 phospholipase C, delta 1
PLK4 polo-like kinase 4
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRR14L proline rich 14-like
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAB28 RAB28, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAB40B RAB40B, member RAS oncogene family
RANBP3 RAN binding protein 3
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPAIN RPA interacting protein
RUNX1 runt-related transcription factor 1
SETDB1 SET domain, bifurcated 1
SF3B3 splicing factor 3b, subunit 3, 130kDa
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SOGA1 suppressor of glucose, autophagy associated 1
SPEG SPEG complex locus
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STAC SH3 and cysteine rich domain
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SYT1 synaptotagmin I
TCF4 transcription factor 4
TELO2 telomere maintenance 2
TESK2 testis-specific kinase 2
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFIP11 tuftelin interacting protein 11
TGOLN2 trans-golgi network protein 2
THOC5 THO complex 5
TTC38 tetratricopeptide repeat domain 38
TXLNG taxilin gamma
UROD uroporphyrinogen decarboxylase
UTRN utrophin
WDR4 WD repeat domain 4
WSB1 WD repeat and SOCS box containing 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZBTB44 zinc finger and BTB domain containing 44
ZNF137P zinc finger protein 137, pseudogene
ZNF197 zinc finger protein 197
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANAPC2 anaphase promoting complex subunit 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATG9A autophagy related 9A
AUP1 ancient ubiquitous protein 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
C17ORF80 chromosome 17 open reading frame 80
CCNT1 cyclin T1
CCRL2 chemokine (C-C motif) receptor-like 2
CHML choroideremia-like (Rab escort protein 2)
CHST10 carbohydrate sulfotransferase 10
CLK1 CDC-like kinase 1
COCH cochlin
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDIT4 DNA-damage-inducible transcript 4
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DPY19L2P2 DPY19L2 pseudogene 2
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EGLN2 egl-9 family hypoxia-inducible factor 2
EPHB6 EPH receptor B6
ETV4 ets variant 4
FADS2 fatty acid desaturase 2
FAM102A family with sequence similarity 102, member A
FAM114A2 family with sequence similarity 114, member A2
FBXW4 F-box and WD repeat domain containing 4
GAA glucosidase, alpha; acid
HIRA histone cell cycle regulator
HYAL3 hyaluronoglucosaminidase 3
ICE2 interactor of little elongation complex ELL subunit 2
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KIAA1549L KIAA1549-like
KLC2 kinesin light chain 2
KRT75 keratin 75, type II
LMNB1 lamin B1
LRP5 low density lipoprotein receptor-related protein 5
MAPK3 mitogen-activated protein kinase 3
MFSD12 major facilitator superfamily domain containing 12
MITF microphthalmia-associated transcription factor
MMP13 matrix metallopeptidase 13
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
NCS1 neuronal calcium sensor 1
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NHEJ1 nonhomologous end-joining factor 1
NOL6 nucleolar protein 6 (RNA-associated)
OCLN occludin
PAQR4 progestin and adipoQ receptor family member IV
PCF11 PCF11 cleavage and polyadenylation factor subunit
PHKG2 phosphorylase kinase, gamma 2 (testis)
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLD2 phospholipase D2
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLH polymerase (DNA directed), eta
PPL periplakin
PPP1R26 protein phosphatase 1, regulatory subunit 26
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB4B RAB4B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RHOBTB1 Rho-related BTB domain containing 1
RNF146 ring finger protein 146
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF25 ring finger protein 25
RPGR retinitis pigmentosa GTPase regulator
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SDC3 syndecan 3
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SIX1 SIX homeobox 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX12 SRY (sex determining region Y)-box 12
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STX18 syntaxin 18
TBC1D10B TBC1 domain family, member 10B
TENM4 teneurin transmembrane protein 4
TGS1 trimethylguanosine synthase 1
THAP1 THAP domain containing, apoptosis associated protein 1
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM57 transmembrane protein 57
TMOD3 tropomodulin 3 (ubiquitous)
TTBK2 tau tubulin kinase 2
TTC23 tetratricopeptide repeat domain 23
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
UBL4A ubiquitin-like 4A
UNKL unkempt family zinc finger-like
WASF2 WAS protein family, member 2
XYLT2 xylosyltransferase II
YIPF3 Yip1 domain family, member 3
ZBED1 zinc finger, BED-type containing 1
ZBTB3 zinc finger and BTB domain containing 3
ZNF177 zinc finger protein 177
ZNF408 zinc finger protein 408