isopropamide iodide-6781 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the isopropamide iodide-6781 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
AKR1C1 aldo-keto reductase family 1, member C1
ANGEL2 angel homolog 2 (Drosophila)
ARHGAP35 Rho GTPase activating protein 35
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
CAV2 caveolin 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEP250 centrosomal protein 250kDa
CFAP45 cilia and flagella associated protein 45
CHKB choline kinase beta
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLCN7 chloride channel, voltage-sensitive 7
CRTC1 CREB regulated transcription coactivator 1
DBF4B DBF4 zinc finger B
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ELP6 elongator acetyltransferase complex subunit 6
ENO2 enolase 2 (gamma, neuronal)
ERCC6 excision repair cross-complementation group 6
ETV7 ets variant 7
EWSR1 EWS RNA-binding protein 1
FAM214B family with sequence similarity 214, member B
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FHL1 four and a half LIM domains 1
GNRHR gonadotropin-releasing hormone receptor
GPR153 G protein-coupled receptor 153
GRIK5 glutamate receptor, ionotropic, kainate 5
HYI hydroxypyruvate isomerase (putative)
ICA1 islet cell autoantigen 1, 69kDa
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
INPP5J inositol polyphosphate-5-phosphatase J
JADE1 jade family PHD finger 1
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCTD7 potassium channel tetramerization domain containing 7
KDM5A lysine (K)-specific demethylase 5A
KREMEN2 kringle containing transmembrane protein 2
KRT32 keratin 32, type I
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LPCAT3 lysophosphatidylcholine acyltransferase 3
MAN1A2 mannosidase, alpha, class 1A, member 2
MBNL2 muscleblind-like splicing regulator 2
MBNL3 muscleblind-like splicing regulator 3
MDM1 Mdm1 nuclear protein homolog (mouse)
MLX MLX, MAX dimerization protein
MMP19 matrix metallopeptidase 19
MRPS18C mitochondrial ribosomal protein S18C
NEB nebulin
NR0B2 nuclear receptor subfamily 0, group B, member 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PARD6B par-6 family cell polarity regulator beta
PCDHA9 protocadherin alpha 9
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDLIM5 PDZ and LIM domain 5
PEX16 peroxisomal biogenesis factor 16
PGAP1 post-GPI attachment to proteins 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLIN2 perilipin 2
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRB3 proline-rich protein BstNI subfamily 3
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB6A RAB6A, member RAS oncogene family
RASAL2 RAS protein activator like 2
RGS20 regulator of G-protein signaling 20
RND1 Rho family GTPase 1
RNF43 ring finger protein 43
RXRB retinoid X receptor, beta
SCAND2P SCAN domain containing 2 pseudogene
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLN sarcolipin
SPTBN1 spectrin, beta, non-erythrocytic 1
STAT5B signal transducer and activator of transcription 5B
STK24 serine/threonine kinase 24
TAS2R1 taste receptor, type 2, member 1
TESC tescalcin
TK2 thymidine kinase 2, mitochondrial
TOR4A torsin family 4, member A
TSC22D2 TSC22 domain family, member 2
TTC38 tetratricopeptide repeat domain 38
VASH2 vasohibin 2
VIPR1 vasoactive intestinal peptide receptor 1
VPS9D1 VPS9 domain containing 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF202 zinc finger protein 202
ZNF224 zinc finger protein 224
ZNF701 zinc finger protein 701
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANXA2P3 annexin A2 pseudogene 3
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARRB1 arrestin, beta 1
ATP13A2 ATPase type 13A2
AUH AU RNA binding protein/enoyl-CoA hydratase
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BBC3 BCL2 binding component 3
C14ORF93 chromosome 14 open reading frame 93
C19ORF40 chromosome 19 open reading frame 40
C7ORF43 chromosome 7 open reading frame 43
CAPG capping protein (actin filament), gelsolin-like
CCDC85C coiled-coil domain containing 85C
CCDC88C coiled-coil domain containing 88C
CCNO cyclin O
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD79B CD79b molecule, immunoglobulin-associated beta
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLK1 CDC-like kinase 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRABP1 cellular retinoic acid binding protein 1
CRY2 cryptochrome circadian clock 2
CTSF cathepsin F
CUL9 cullin 9
DAGLA diacylglycerol lipase, alpha
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EXD3 exonuclease 3'-5' domain containing 3
F2R coagulation factor II (thrombin) receptor
FMO4 flavin containing monooxygenase 4
FRS2 fibroblast growth factor receptor substrate 2
GATA4 GATA binding protein 4
GNL1 guanine nucleotide binding protein-like 1
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
GSTCD glutathione S-transferase, C-terminal domain containing
GSTM4 glutathione S-transferase mu 4
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HDAC7 histone deacetylase 7
HIST1H4D histone cluster 1, H4d
HPN hepsin
IDI2-AS1 IDI2 antisense RNA 1
IL17RA interleukin 17 receptor A
KIAA0319L KIAA0319-like
LIF leukemia inhibitory factor
LIME1 Lck interacting transmembrane adaptor 1
LINC00115 long intergenic non-protein coding RNA 115
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MATK megakaryocyte-associated tyrosine kinase
MBTPS2 membrane-bound transcription factor peptidase, site 2
MTERF4 mitochondrial transcription termination factor 4
NBAS neuroblastoma amplified sequence
NNAT neuronatin
NUP62CL nucleoporin 62kDa C-terminal like
OSGIN1 oxidative stress induced growth inhibitor 1
OVGP1 oviductal glycoprotein 1, 120kDa
PCDH12 protocadherin 12
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PRODH proline dehydrogenase (oxidase) 1
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTDSS2 phosphatidylserine synthase 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RGS2 regulator of G-protein signaling 2
RHBDD3 rhomboid domain containing 3
RHBG Rh family, B glycoprotein (gene/pseudogene)
S100A9 S100 calcium binding protein A9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLIT2 slit homolog 2 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SYCP2 synaptonemal complex protein 2
TCHH trichohyalin
TEP1 telomerase-associated protein 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNS2 tensin 2
TPCN1 two pore segment channel 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSC22D4 TSC22 domain family, member 4
TTC33 tetratricopeptide repeat domain 33
TUBA3C tubulin, alpha 3c
USP27X ubiquitin specific peptidase 27, X-linked
YY2 YY2 transcription factor
ZBTB48 zinc finger and BTB domain containing 48
ZFHX3 zinc finger homeobox 3
ZNF141 zinc finger protein 141
ZNF205 zinc finger protein 205
ZNF747 zinc finger protein 747