isoetarine-2711 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the isoetarine-2711 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ANXA2P2 annexin A2 pseudogene 2
AOAH acyloxyacyl hydrolase (neutrophil)
ARL4C ADP-ribosylation factor-like 4C
AXL AXL receptor tyrosine kinase
BCL6 B-cell CLL/lymphoma 6
BFSP2 beaded filament structural protein 2, phakinin
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CCL20 chemokine (C-C motif) ligand 20
CD1A CD1a molecule
CD38 CD38 molecule
CD86 CD86 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDO1 cysteine dioxygenase type 1
CEP41 centrosomal protein 41kDa
CHN2 chimerin 2
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CIB2 calcium and integrin binding family member 2
CLEC2D C-type lectin domain family 2, member D
COL9A3 collagen, type IX, alpha 3
CREM cAMP responsive element modulator
CSRP2 cysteine and glycine-rich protein 2
CTSF cathepsin F
CTSL cathepsin L
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYTH1 cytohesin 1
DNAH17 dynein, axonemal, heavy chain 17
DNASE2 deoxyribonuclease II, lysosomal
DOCK4 dedicator of cytokinesis 4
DPY19L1 dpy-19-like 1 (C. elegans)
DUSP4 dual specificity phosphatase 4
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHB3 EPH receptor B3
ERN1 endoplasmic reticulum to nucleus signaling 1
EXTL3 exostosin-like glycosyltransferase 3
FADS3 fatty acid desaturase 3
FAM13A family with sequence similarity 13, member A
FBXL7 F-box and leucine-rich repeat protein 7
FNTB farnesyltransferase, CAAX box, beta
FOSL2 FOS-like antigen 2
FOXC1 forkhead box C1
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GLI3 GLI family zinc finger 3
GNLY granulysin
GPR161 G protein-coupled receptor 161
GPR183 G protein-coupled receptor 183
GRK5 G protein-coupled receptor kinase 5
HIST1H3G histone cluster 1, H3g
HLA-DRA major histocompatibility complex, class II, DR alpha
HOXC10 homeobox C10
IFT27 intraflagellar transport 27
IL1R1 interleukin 1 receptor, type I
ISG20 interferon stimulated exonuclease gene 20kDa
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIDINS220 kinase D-interacting substrate, 220kDa
KIF24 kinesin family member 24
KIFC3 kinesin family member C3
KYNU kynureninase
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
MEF2C myocyte enhancer factor 2C
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NPAS2 neuronal PAS domain protein 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
PBX2 pre-B-cell leukemia homeobox 2
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCD1 phospholipase C, delta 1
PLSCR1 phospholipid scramblase 1
PNOC prepronociceptin
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRB4 proline-rich protein BstNI subfamily 4
RANBP3 RAN binding protein 3
RASAL1 RAS protein activator like 1 (GAP1 like)
RASAL2 RAS protein activator like 2
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAND2P SCAN domain containing 2 pseudogene
SDC2 syndecan 2
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SNPH syntaphilin
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST7L suppression of tumorigenicity 7 like
STAT2 signal transducer and activator of transcription 2, 113kDa
TAC3 tachykinin 3
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THBS1 thrombospondin 1
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM2 transmembrane protein 2
TMEM51 transmembrane protein 51
TNC tenascin C
TRIM62 tripartite motif containing 62
VPS9D1 VPS9 domain containing 1
ZNF205 zinc finger protein 205

decreased expression

Symbol Name
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKRD40 ankyrin repeat domain 40
ARID5A AT rich interactive domain 5A (MRF1-like)
ARMCX4 armadillo repeat containing, X-linked 4
BAHCC1 BAH domain and coiled-coil containing 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
BBC3 BCL2 binding component 3
BPHL biphenyl hydrolase-like (serine hydrolase)
CARD9 caspase recruitment domain family, member 9
CCDC132 coiled-coil domain containing 132
CCDC86 coiled-coil domain containing 86
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CORT cortistatin
CRYGC crystallin, gamma C
DEFB1 defensin, beta 1
DOC2A double C2-like domains, alpha
DSPP dentin sialophosphoprotein
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
EIF5A2 eukaryotic translation initiation factor 5A2
ELP6 elongator acetyltransferase complex subunit 6
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRS3 fibroblast growth factor receptor substrate 3
GIPC1 GIPC PDZ domain containing family, member 1
GPC3 glypican 3
GRIP2 glutamate receptor interacting protein 2
HCAR3 hydroxycarboxylic acid receptor 3
HDAC9 histone deacetylase 9
HIST1H2AI histone cluster 1, H2ai
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
ISOC2 isochorismatase domain containing 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JMJD4 jumonji domain containing 4
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KLF1 Kruppel-like factor 1 (erythroid)
LAMP5 lysosomal-associated membrane protein family, member 5
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP3 low density lipoprotein receptor-related protein 3
LRP5 low density lipoprotein receptor-related protein 5
LTBP3 latent transforming growth factor beta binding protein 3
LY6E lymphocyte antigen 6 complex, locus E
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
METTL16 methyltransferase like 16
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYBBP1A MYB binding protein (P160) 1a
NBEA neurobeachin
NCALD neurocalcin delta
NDE1 nudE neurodevelopment protein 1
NEUROD4 neuronal differentiation 4
NIPAL2 NIPA-like domain containing 2
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NTSR1 neurotensin receptor 1 (high affinity)
NUBPL nucleotide binding protein-like
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PDE12 phosphodiesterase 12
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PKD2L2 polycystic kidney disease 2-like 2
POM121 POM121 transmembrane nucleoporin
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RANBP17 RAN binding protein 17
RBM15B RNA binding motif protein 15B
REC8 REC8 meiotic recombination protein
RNF126P1 ring finger protein 126 pseudogene 1
RNF144A ring finger protein 144A
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SCGB2A2 secretoglobin, family 2A, member 2
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMYD5 SMYD family member 5
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STRN4 striatin, calmodulin binding protein 4
STX17 syntaxin 17
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBC1D30 TBC1 domain family, member 30
TERT telomerase reverse transcriptase
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM104 transmembrane protein 104
TSC22D4 TSC22 domain family, member 4
TTC27 tetratricopeptide repeat domain 27
UBIAD1 UbiA prenyltransferase domain containing 1
USB1 U6 snRNA biogenesis 1
USP36 ubiquitin specific peptidase 36
USP6NL USP6 N-terminal like
VASH2 vasohibin 2
ZNF276 zinc finger protein 276
ZNF76 zinc finger protein 76