isocorydine-6843 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the isocorydine-6843 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
AJAP1 adherens junctions associated protein 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALOX5 arachidonate 5-lipoxygenase
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APOE apolipoprotein E
APOL6 apolipoprotein L, 6
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARMCX4 armadillo repeat containing, X-linked 4
ASPN asporin
BAZ2A bromodomain adjacent to zinc finger domain, 2A
C14ORF1 chromosome 14 open reading frame 1
C1ORF61 chromosome 1 open reading frame 61
C2ORF27A chromosome 2 open reading frame 27A
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCDC88A coiled-coil domain containing 88A
CCL27 chemokine (C-C motif) ligand 27
CD8A CD8a molecule
CHD5 chromodomain helicase DNA binding protein 5
CLCN7 chloride channel, voltage-sensitive 7
CLSTN2 calsyntenin 2
CNGB3 cyclic nucleotide gated channel beta 3
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DICER1 dicer 1, ribonuclease type III
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EHBP1L1 EH domain binding protein 1-like 1
ESRRA estrogen-related receptor alpha
FAM63B family with sequence similarity 63, member B
FGF18 fibroblast growth factor 18
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIP2 glutamate receptor interacting protein 2
GRM1 glutamate receptor, metabotropic 1
HCRTR2 hypocretin (orexin) receptor 2
HFE hemochromatosis
HLA-DOA major histocompatibility complex, class II, DO alpha
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP3 insulin-like growth factor binding protein 3
ITPK1 inositol-tetrakisphosphate 1-kinase
IVL involucrin
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LPAR1 lysophosphatidic acid receptor 1
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MED16 mediator complex subunit 16
MOB3B MOB kinase activator 3B
MYL10 myosin, light chain 10, regulatory
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO9B myosin IXB
NFIB nuclear factor I/B
NLRX1 NLR family member X1
NOD2 nucleotide-binding oligomerization domain containing 2
NT5M 5',3'-nucleotidase, mitochondrial
NUPR1 nuclear protein, transcriptional regulator, 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PALMD palmdelphin
PHLDA1 pleckstrin homology-like domain, family A, member 1
PICK1 protein interacting with PRKCA 1
PLEK pleckstrin
PLK3 polo-like kinase 3
PLSCR1 phospholipid scramblase 1
POU3F4 POU class 3 homeobox 4
PPARD peroxisome proliferator-activated receptor delta
PRKCA protein kinase C, alpha
PRKG2 protein kinase, cGMP-dependent, type II
PVT1 Pvt1 oncogene (non-protein coding)
RAB3B RAB3B, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RANBP1 RAN binding protein 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RYR1 ryanodine receptor 1 (skeletal)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SIPA1 signal-induced proliferation-associated 1
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYNGR1 synaptogyrin 1
TAOK2 TAO kinase 2
TCP11L1 t-complex 11, testis-specific-like 1
TPSG1 tryptase gamma 1
TSC2 tuberous sclerosis 2
TUBB2B tubulin, beta 2B class IIb
UGT8 UDP glycosyltransferase 8
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF532 zinc finger protein 532
ZNF589 zinc finger protein 589
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ALPK1 alpha-kinase 1
ANKRD40 ankyrin repeat domain 40
APOD apolipoprotein D
B9D2 B9 protein domain 2
BBC3 BCL2 binding component 3
BCL2L2 BCL2-like 2
BEX4 brain expressed, X-linked 4
C19ORF73 chromosome 19 open reading frame 73
C1ORF105 chromosome 1 open reading frame 105
C7ORF43 chromosome 7 open reading frame 43
CAMK1D calcium/calmodulin-dependent protein kinase ID
CENPO centromere protein O
CHKB choline kinase beta
CLIP4 CAP-GLY domain containing linker protein family, member 4
CORT cortistatin
CSF1R colony stimulating factor 1 receptor
CXADR coxsackie virus and adenovirus receptor
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAL4 dynein, axonemal, light chain 4
EGFL7 EGF-like-domain, multiple 7
ERN1 endoplasmic reticulum to nucleus signaling 1
EXD3 exonuclease 3'-5' domain containing 3
F2R coagulation factor II (thrombin) receptor
FAM46C family with sequence similarity 46, member C
FOXN2 forkhead box N2
FRK fyn-related Src family tyrosine kinase
GAMT guanidinoacetate N-methyltransferase
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPX2 glutathione peroxidase 2
HDAC11 histone deacetylase 11
HIST1H2AJ histone cluster 1, H2aj
HYI hydroxypyruvate isomerase (putative)
KIAA0895 KIAA0895
KPTN kaptin (actin binding protein)
LHX6 LIM homeobox 6
LOC730101 uncharacterized LOC730101
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRRC61 leucine rich repeat containing 61
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP1S microtubule-associated protein 1S
MAST3 microtubule associated serine/threonine kinase 3
MED24 mediator complex subunit 24
METTL16 methyltransferase like 16
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MXD3 MAX dimerization protein 3
NCAM2 neural cell adhesion molecule 2
NDE1 nudE neurodevelopment protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NRSN2 neurensin 2
NUP62CL nucleoporin 62kDa C-terminal like
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PECR peroxisomal trans-2-enoyl-CoA reductase
PEX26 peroxisomal biogenesis factor 26
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLD2 phospholipase D2
PLEKHO2 pleckstrin homology domain containing, family O member 2
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRF1 perforin 1 (pore forming protein)
PRODH proline dehydrogenase (oxidase) 1
PROS1 protein S (alpha)
RAB3A RAB3A, member RAS oncogene family
RFTN1 raftlin, lipid raft linker 1
RHOBTB2 Rho-related BTB domain containing 2
ROM1 retinal outer segment membrane protein 1
RPAP2 RNA polymerase II associated protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
S100A9 S100 calcium binding protein A9
SAYSD1 SAYSVFN motif domain containing 1
SCRN3 secernin 3
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMIM14 small integral membrane protein 14
STK16 serine/threonine kinase 16
STRA6 stimulated by retinoic acid 6
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAOK1 TAO kinase 1
TRAIP TRAF interacting protein
TTBK2 tau tubulin kinase 2
VASH2 vasohibin 2
WRN Werner syndrome, RecQ helicase-like
ZNF34 zinc finger protein 34
ZNF365 zinc finger protein 365
ZSCAN26 zinc finger and SCAN domain containing 26