isocorydine-4505 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the isocorydine-4505 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
AIRE autoimmune regulator
AKAP6 A kinase (PRKA) anchor protein 6
ANGPTL4 angiopoietin-like 4
APAF1 apoptotic peptidase activating factor 1
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARSD arylsulfatase D
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
C11ORF16 chromosome 11 open reading frame 16
C5AR2 complement component 5a receptor 2
CA5B carbonic anhydrase VB, mitochondrial
CALCR calcitonin receptor
CD68 CD68 molecule
CDK13 cyclin-dependent kinase 13
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CELA2A chymotrypsin-like elastase family, member 2A
COL3A1 collagen, type III, alpha 1
COL9A3 collagen, type IX, alpha 3
CPB2 carboxypeptidase B2 (plasma)
CRHR2 corticotropin releasing hormone receptor 2
DMRT1 doublesex and mab-3 related transcription factor 1
DNAI2 dynein, axonemal, intermediate chain 2
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
ECE1 endothelin converting enzyme 1
EPHB1 EPH receptor B1
EPN1 epsin 1
FAIM2 Fas apoptotic inhibitory molecule 2
FGF22 fibroblast growth factor 22
FGFR4 fibroblast growth factor receptor 4
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
HDAC6 histone deacetylase 6
HEG1 heart development protein with EGF-like domains 1
HEMK1 HemK methyltransferase family member 1
HIC2 hypermethylated in cancer 2
HIST1H3I histone cluster 1, H3i
HPX hemopexin
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IGLL1 immunoglobulin lambda-like polypeptide 1
IL1RN interleukin 1 receptor antagonist
IQCC IQ motif containing C
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIAA1467 KIAA1467
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLHL25 kelch-like family member 25
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LINC00302 long intergenic non-protein coding RNA 302
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MRPS18C mitochondrial ribosomal protein S18C
MUSK muscle, skeletal, receptor tyrosine kinase
MVD mevalonate (diphospho) decarboxylase
NOVA2 neuro-oncological ventral antigen 2
NRIP3 nuclear receptor interacting protein 3
NSUN6 NOP2/Sun domain family, member 6
OSBP2 oxysterol binding protein 2
OSBPL7 oxysterol binding protein-like 7
PARP8 poly (ADP-ribose) polymerase family, member 8
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP4 peptidoglycan recognition protein 4
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PRDX2 peroxiredoxin 2
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTCRA pre T-cell antigen receptor alpha
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS14 regulator of G-protein signaling 14
RGS3 regulator of G-protein signaling 3
RHO rhodopsin
RUNX1 runt-related transcription factor 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SMAD1 SMAD family member 1
SPEF1 sperm flagellar 1
SPHK2 sphingosine kinase 2
SPRR3 small proline-rich protein 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STOML1 stomatin (EPB72)-like 1
STRA6 stimulated by retinoic acid 6
SUGP1 SURP and G patch domain containing 1
TAPT1 transmembrane anterior posterior transformation 1
TIMELESS timeless circadian clock
TMEM74B transmembrane protein 74B
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRIM15 tripartite motif containing 15
UNC93B1 unc-93 homolog B1 (C. elegans)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WDR78 WD repeat domain 78
ZFP64 ZFP64 zinc finger protein
ZHX3 zinc fingers and homeoboxes 3

decreased expression

Symbol Name
AADAC arylacetamide deacetylase
ABHD8 abhydrolase domain containing 8
ACPP acid phosphatase, prostate
AFF4 AF4/FMR2 family, member 4
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AURKC aurora kinase C
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BEX1 brain expressed, X-linked 1
BICC1 BicC family RNA binding protein 1
BTBD18 BTB (POZ) domain containing 18
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF79 chromosome 14 open reading frame 79
C14ORF93 chromosome 14 open reading frame 93
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CBX8 chromobox homolog 8
CD82 CD82 molecule
CDHR2 cadherin-related family member 2
CENPJ centromere protein J
CGREF1 cell growth regulator with EF-hand domain 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CISH cytokine inducible SH2-containing protein
CNGB3 cyclic nucleotide gated channel beta 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNTLN centlein, centrosomal protein
COBL cordon-bleu WH2 repeat protein
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CSRNP3 cysteine-serine-rich nuclear protein 3
CYB5R2 cytochrome b5 reductase 2
DGKE diacylglycerol kinase, epsilon 64kDa
ELMO3 engulfment and cell motility 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM120C family with sequence similarity 120C
FAM155A family with sequence similarity 155, member A
FAM204A family with sequence similarity 204, member A
FGL1 fibrinogen-like 1
GAREM GRB2 associated, regulator of MAPK1
GAS2 growth arrest-specific 2
GMPR guanosine monophosphate reductase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BM histone cluster 1, H2bm
HIST1H4C histone cluster 1, H4c
HIST2H2AA3 histone cluster 2, H2aa3
HOXB2 homeobox B2
HOXC5 homeobox C5
IL33 interleukin 33
IQSEC2 IQ motif and Sec7 domain 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1551 KIAA1551
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LDHC lactate dehydrogenase C
LOC257152 uncharacterized LOC257152
LPPR1 lipid phosphate phosphatase-related protein type 1
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRK1 leucine-rich repeat kinase 1
MANBA mannosidase, beta A, lysosomal
MDM4 MDM4, p53 regulator
MON1B MON1 secretory trafficking family member B
MYL5 myosin, light chain 5, regulatory
MYOZ3 myozenin 3
NDP Norrie disease (pseudoglioma)
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NPIPB15 nuclear pore complex interacting protein family, member B15
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5M 5',3'-nucleotidase, mitochondrial
PARM1 prostate androgen-regulated mucin-like protein 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PODXL2 podocalyxin-like 2
POU3F2 POU class 3 homeobox 2
PRB3 proline-rich protein BstNI subfamily 3
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
RNF43 ring finger protein 43
SECISBP2 SECIS binding protein 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYNGR3 synaptogyrin 3
TMEM206 transmembrane protein 206
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRAIP TRAF interacting protein
TRDMT1 tRNA aspartic acid methyltransferase 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP36 ubiquitin specific peptidase 36
WFDC2 WAP four-disulfide core domain 2
ZNF197 zinc finger protein 197
ZNF214 zinc finger protein 214
ZNF286A zinc finger protein 286A
ZNF667 zinc finger protein 667
ZNF84 zinc finger protein 84
ZNF862 zinc finger protein 862