ischemic Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

471 genes co-occuring with the biological term ischemic in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACAT1 acetyl-CoA acetyltransferase 1
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACTA2 actin, alpha 2, smooth muscle, aorta
ADA adenosine deaminase
ADAM17 ADAM metallopeptidase domain 17
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADD1 adducin 1 (alpha)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADORA1 adenosine A1 receptor
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRA2C adrenoceptor alpha 2C
ADRB2 adrenoceptor beta 2, surface
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AHSG alpha-2-HS-glycoprotein
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALCAM activated leukocyte cell adhesion molecule
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX15 arachidonate 15-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMBP alpha-1-microglobulin/bikunin precursor
AMPD1 adenosine monophosphate deaminase 1
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANGPTL4 angiopoietin-like 4
ANXA5 annexin A5
AOC3 amine oxidase, copper containing 3
APIP APAF1 interacting protein
APOA1 apolipoprotein A-I
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
APOM apolipoprotein M
AQP1 aquaporin 1 (Colton blood group)
AQP4 aquaporin 4
ARID1B AT rich interactive domain 1B (SWI1-like)
ATF3 activating transcription factor 3
ATP13A2 ATPase type 13A2
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
ATXN1 ataxin 1
BCL2 B-cell CLL/lymphoma 2
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
BMP7 bone morphogenetic protein 7
BRAP BRCA1 associated protein
C3 complement component 3
C4B complement component 4B (Chido blood group)
C5 complement component 5
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CARD8 caspase recruitment domain family, member 8
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBR1 carbonyl reductase 1
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCR2 chemokine (C-C motif) receptor 2
CD28 CD28 molecule
CD34 CD34 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDC42 cell division cycle 42
CDKN2B-AS1 CDKN2B antisense RNA 1
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CETP cholesteryl ester transfer protein, plasma
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CKM creatine kinase, muscle
CLEC16A C-type lectin domain family 16, member A
CNR1 cannabinoid receptor 1 (brain)
CNSN Carnosinemia (carnosinase)
COL4A1 collagen, type IV, alpha 1
COL5A2 collagen, type V, alpha 2
CP ceruloplasmin (ferroxidase)
CPB2 carboxypeptidase B2 (plasma)
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSF3R colony stimulating factor 3 receptor (granulocyte)
CST3 cystatin C
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSL cathepsin L
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
CYSLTR1 cysteinyl leukotriene receptor 1
DAXX death-domain associated protein
DCN decorin
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DEFB4A defensin, beta 4A
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLL4 delta-like 4 (Drosophila)
DSP desmoplakin
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EFNB2 ephrin-B2
EGLN2 egl-9 family hypoxia-inducible factor 2
EGR1 early growth response 1
ELAVL1 ELAV like RNA binding protein 1
ENO2 enolase 2 (gamma, neuronal)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHX2 epoxide hydrolase 2, cytoplasmic
EPO erythropoietin
EPOR erythropoietin receptor
ESR1 estrogen receptor 1
F11 coagulation factor XI
F12 coagulation factor XII (Hageman factor)
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
FABP3 fatty acid binding protein 3, muscle and heart
FABP4 fatty acid binding protein 4, adipocyte
FABP7 fatty acid binding protein 7, brain
FAS Fas cell surface death receptor
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGF2 fibroblast growth factor 2 (basic)
FGFR4 fibroblast growth factor receptor 4
FGG fibrinogen gamma chain
FOXO1 forkhead box O1
FOXO4 forkhead box O4
FRMD4B FERM domain containing 4B
FSTL1 follistatin-like 1
GCH1 GTP cyclohydrolase 1
GCK glucokinase (hexokinase 4)
GCKR glucokinase (hexokinase 4) regulator
GDNF glial cell derived neurotrophic factor
GFAP glial fibrillary acidic protein
GGT1 gamma-glutamyltransferase 1
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GJA4 gap junction protein, alpha 4, 37kDa
GJA5 gap junction protein, alpha 5, 40kDa
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP6 glycoprotein VI (platelet)
GP9 glycoprotein IX (platelet)
GPX1 glutathione peroxidase 1
GPX3 glutathione peroxidase 3
GSK3B glycogen synthase kinase 3 beta
GSTA4 glutathione S-transferase alpha 4
GSTM1 glutathione S-transferase mu 1
GSTO1 glutathione S-transferase omega 1
GSTT1 glutathione S-transferase theta 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HABP2 hyaluronan binding protein 2
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HBA1 hemoglobin, alpha 1
HDLCQ1 high density lipoprotein cholesterol level QTL 1
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HP haptoglobin
HRH3 histamine receptor H3
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSF1 heat shock transcription factor 1
HSPA1A heat shock 70kDa protein 1A
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HVCN1 hydrogen voltage gated channel 1
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IFN1@ interferon, type 1, cluster
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL10RB interleukin 10 receptor, beta
IL11 interleukin 11
IL16 interleukin 16
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL20 interleukin 20
IL21 interleukin 21
IL27 interleukin 27
IL33 interleukin 33
IL4 interleukin 4
IL5RA interleukin 5 receptor, alpha
IL6 interleukin 6
ILK integrin-linked kinase
INHBA inhibin, beta A
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IRF1 interferon regulatory factor 1
IRF2BP2 interferon regulatory factor 2 binding protein 2
IRX4 iroquois homeobox 4
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA7 integrin, alpha 7
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITLN1 intelectin 1 (galactofuranose binding)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JAK2 Janus kinase 2
KALRN kalirin, RhoGEF kinase
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK17 potassium channel, two pore domain subfamily K, member 17
KDR kinase insert domain receptor
KIF6 kinesin family member 6
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLK1 kallikrein 1
KLKB1 kallikrein B, plasma (Fletcher factor) 1
LCN2 lipocalin 2
LEP leptin
LEPQTL1 Leptin, serum levels of
LGALS13 lectin, galactoside-binding, soluble, 13
LIPC lipase, hepatic
LMO4 LIM domain only 4
LOX lysyl oxidase
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
LTA lymphotoxin alpha
LTA4H leukotriene A4 hydrolase
LTB4R leukotriene B4 receptor
LTB4R2 leukotriene B4 receptor 2
LTC4S leukotriene C4 synthase
LTF lactotransferrin
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MEFV Mediterranean fever
MEPE matrix extracellular phosphoglycoprotein
MET MET proto-oncogene, receptor tyrosine kinase
MGP matrix Gla protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR124-1 microRNA 124-1
MIR124-2 microRNA 124-2
MIR124-3 microRNA 124-3
MIR126 microRNA 126
MIR144 microRNA 144
MIR145 microRNA 145
MIR146A microRNA 146a
MIR149 microRNA 149
MIR16-1 microRNA 16-1
MIR17HG miR-17-92 cluster host gene
MIR196A2 microRNA 196a-2
MIR210 microRNA 210
MIR223 microRNA 223
MIR24-1 microRNA 24-1
MIR24-2 microRNA 24-2
MIR30A microRNA 30a
MIR34A microRNA 34a
MIR499A microRNA 499a
MIRLET7B microRNA let-7b
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTAP methylthioadenosine phosphorylase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MTTP microsomal triglyceride transfer protein
MX1 MX dynamin-like GTPase 1
MYD88 myeloid differentiation primary response 88
NAMPT nicotinamide phosphoribosyltransferase
NCAM1 neural cell adhesion molecule 1
ND1
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NGB neuroglobin
NINJ2 ninjurin 2
NLGN1 neuroligin 1
NLRP3 NLR family, pyrin domain containing 3
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH3 notch 3
NOX4 NADPH oxidase 4
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPR1 natriuretic peptide receptor 1
NPR3 natriuretic peptide receptor 3
NPY neuropeptide Y
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRG1 neuregulin 1
NTF3 neurotrophin 3
NTNG1 netrin G1
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OXT oxytocin/neurophysin I prepropeptide
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP1 poly (ADP-ribose) polymerase 1
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFD platelet derived growth factor D
PECAM1 platelet/endothelial cell adhesion molecule 1
PEPD peptidase D
PEX2 peroxisomal biogenesis factor 2
PHB prohibitin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLA2G15 phospholipase A2, group XV
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
PLSCR1 phospholipid scramblase 1
PLXND1 plexin D1
PNOC prepronociceptin
PON1 paraoxonase 1
PON2 paraoxonase 2
POU5F1 POU class 5 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PRDX2 peroxiredoxin 2
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCH protein kinase C, eta
PRL prolactin
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROM1 prominin 1
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTMA prothymosin, alpha
PTX3 pentraxin 3, long
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RETN resistin
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RNF213 ring finger protein 213
RNLS renalase, FAD-dependent amine oxidase
ROPN1 rhophilin associated tail protein 1
S100B S100 calcium binding protein B
SAA1 serum amyloid A1
SCN5A sodium channel, voltage gated, type V alpha subunit
SCUBE1 signal peptide, CUB domain, EGF-like 1
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SHH sonic hedgehog
SIRT1 sirtuin 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SPP1 secreted phosphoprotein 1
SPTBN5 spectrin, beta, non-erythrocytic 5
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
SRSF3 serine/arginine-rich splicing factor 3
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STIP1 stress-induced phosphoprotein 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TCN2 transcobalamin II
TF transferrin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
THBD thrombomodulin
THBS1 thrombospondin 1
THPO thrombopoietin
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TJP1 tight junction protein 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNNI3 troponin I type 3 (cardiac)
TNNI3K TNNI3 interacting kinase
TNNT2 troponin T type 2 (cardiac)
TP53 tumor protein p53
TRIB1 tribbles pseudokinase 1
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TTN titin
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VASP vasodilator-stimulated phosphoprotein
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C
VIMP VCP-interacting membrane selenoprotein
VKORC1 vitamin K epoxide reductase complex, subunit 1
VNN1 vanin 1
VWF von Willebrand factor
WARS tryptophanyl-tRNA synthetase
WDR83 WD repeat domain 83
XBP1 X-box binding protein 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZC3H12A zinc finger CCCH-type containing 12A
ZNF202 zinc finger protein 202