ischemia Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION. (Experimental Factor Ontology, EFO_0000556)
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Genes

74 proteins co-occuring with the biological term ischemia in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
AKT1 v-akt murine thymoma viral oncogene homolog 1
ASIC1 acid sensing (proton gated) ion channel 1
ATF2 activating transcription factor 2
BAD BCL2-associated agonist of cell death
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAV1 caveolin 1, caveolae protein, 22kDa
CREB1 cAMP responsive element binding protein 1
CRTC1 CREB regulated transcription coactivator 1
CRYAB crystallin, alpha B
DAPK1 death-associated protein kinase 1
DAXX death-domain associated protein
DLG4 discs, large homolog 4 (Drosophila)
DPYSL2 dihydropyrimidinase-like 2
DUSP1 dual specificity phosphatase 1
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GFAP glial fibrillary acidic protein
GJA1 gap junction protein, alpha 1, 43kDa
GOLGA3 golgin A3
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HSPA1A heat shock 70kDa protein 1A
IRS1 insulin receptor substrate 1
JUN jun proto-oncogene
KDR kinase insert domain receptor
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MDM4 MDM4, p53 regulator
MYBPC3 myosin binding protein C, cardiac
MYL9 myosin, light chain 9, regulatory
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDIA3 protein disulfide isomerase family A, member 3
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFN1 profilin 1
PKN1 protein kinase N1
PLN phospholamban
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCD protein kinase C, delta
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RYR2 ryanodine receptor 2 (cardiac)
SCN5A sodium channel, voltage gated, type V alpha subunit
SIK2 salt-inducible kinase 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SYN1 synapsin I
TNNI3 troponin I type 3 (cardiac)
TTN titin