iris disease Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:240
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Genes

108 genes associated with the disease iris disease in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 4.17572
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 3.88225
OCA2 oculocutaneous albinism II 3.70587
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 3.01904
AFG3L1P AFG3-like AAA ATPase 1, pseudogene 2.61779
ZNF276 zinc finger protein 276 2.42027
DPEP1 dipeptidase 1 (renal) 2.40324
SPATA33 spermatogenesis associated 33 2.38712
SPIRE2 spire-type actin nucleation factor 2 2.27777
CDK10 cyclin-dependent kinase 10 2.19377
FANCA Fanconi anemia, complementation group A 2.1728
CHMP1A charged multivesicular body protein 1A 2.07674
PRDM7 PR domain containing 7 2.01742
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 1.98555
ANKRD11 ankyrin repeat domain 11 1.90969
TYR tyrosinase 1.83309
IRF4 interferon regulatory factor 4 1.82268
SPATA2L spermatogenesis associated 2-like 1.75142
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 1.74243
CPNE7 copine VII 1.73597
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 1.71093
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1 1.68078
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.5865
TTC3 tetratricopeptide repeat domain 3 1.55738
GAS8 growth arrest-specific 8 1.52677
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 1.46556
ZNF778 zinc finger protein 778 1.45937
CENPBD1 CENPB DNA-binding domains containing 1 1.40981
VASH2 vasohibin 2 1.33186
FBXL17 F-box and leucine-rich repeat protein 17 1.19386
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 1.19386
MTG2 mitochondrial ribosome-associated GTPase 2 0.958374
FLNB filamin B, beta 0.838141
KDM7A lysine (K)-specific demethylase 7A 0.831584
AKAP12 A kinase (PRKA) anchor protein 12 0.830304
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 0.794247
PFKL phosphofructokinase, liver 0.769887
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 0.764084
TMEM45A transmembrane protein 45A 0.738669
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.716372
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 0.716372
DOCK2 dedicator of cytokinesis 2 0.69773
ARMC4 armadillo repeat containing 4 0.668836
KLHL3 kelch-like family member 3 0.644215
MEP1A meprin A, alpha (PABA peptide hydrolase) 0.644215
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.638972
TRIM62 tripartite motif containing 62 0.638972
ZDHHC21 zinc finger, DHHC-type containing 21 0.638972
RUFY3 RUN and FYVE domain containing 3 0.638972
CNOT11 CCR4-NOT transcription complex, subunit 11 0.634147
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.634147
CDK6 cyclin-dependent kinase 6 0.629714
TANGO6 transport and golgi organization 6 homolog (Drosophila) 0.611686
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.605359
IVD isovaleryl-CoA dehydrogenase 0.605359
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 0.60243
GUCA1C guanylate cyclase activator 1C 0.60243
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.60243
COPB1 coatomer protein complex, subunit beta 1 0.59964
ZNF704 zinc finger protein 704 0.596808
DDA1 DET1 and DDB1 associated 1 0.594024
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 0.591358
PARL presenilin associated, rhomboid-like 0.591358
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.591358
ZNF30 zinc finger protein 30 0.586345
SASH1 SAM and SH3 domain containing 1 0.586345
TCN2 transcobalamin II 0.583982
SPTA1 spectrin, alpha, erythrocytic 1 0.583982
ZNF792 zinc finger protein 792 0.581707
USO1 USO1 vesicle transport factor 0.570595
GFRA1 GDNF family receptor alpha 1 0.564921
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 0.564734
HEPHL1 hephaestin-like 1 0.562845
ZC3H4 zinc finger CCCH-type containing 4 0.560918
GRSF1 G-rich RNA sequence binding factor 1 0.559045
ICA1L islet cell autoantigen 1,69kDa-like 0.559045
HSPA8 heat shock 70kDa protein 8 0.557222
ELOVL6 ELOVL fatty acid elongase 6 0.557222
NUP35 nucleoporin 35kDa 0.553891
RLF rearranged L-myc fusion 0.550393
C7ORF50 chromosome 7 open reading frame 50 0.54879
NAGA N-acetylgalactosaminidase, alpha- 0.54879
TBCD tubulin folding cofactor D 0.545697
USP44 ubiquitin specific peptidase 44 0.542589
C8ORF34 chromosome 8 open reading frame 34 0.536671
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.536671
STPG2 sperm-tail PG-rich repeat containing 2 0.532547
ANPEP alanyl (membrane) aminopeptidase 0.529931
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2 0.527413
MATN2 matrilin 2 0.526798
TRAF3IP2-AS1 TRAF3IP2 antisense RNA 1 0.523798
FAM222B family with sequence similarity 222, member B 0.521489
FAM117B family with sequence similarity 117, member B 0.519258
CRX cone-rod homeobox 0.5171
CELA3A chymotrypsin-like elastase family, member 3A 0.5171
BPTF bromodomain PHD finger transcription factor 0.516047
CCDC33 coiled-coil domain containing 33 0.51501
MRPL30 mitochondrial ribosomal protein L30 0.512985
TRAF4 TNF receptor-associated factor 4 0.505894
LIN7B lin-7 homolog B (C. elegans) 0.505194
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 0.505194
ANGEL2 angel homolog 2 (Drosophila) 0.504504
KNSTRN kinetochore-localized astrin/SPAG5 binding protein 0.502485
DBF4 DBF4 zinc finger 0.501829
CEP192 centrosomal protein 192kDa 0.498668
SLC25A40 solute carrier family 25, member 40 0.49686
CNTNAP2 contactin associated protein-like 2 0.426309
COL11A1 collagen, type XI, alpha 1 0.418868