ioversol-3365 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the ioversol-3365 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADORA1 adenosine A1 receptor
AKAP8L A kinase (PRKA) anchor protein 8-like
AKT2 v-akt murine thymoma viral oncogene homolog 2
APAF1 apoptotic peptidase activating factor 1
APOM apolipoprotein M
ARMCX4 armadillo repeat containing, X-linked 4
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BCAN brevican
C19ORF66 chromosome 19 open reading frame 66
C1QTNF1 C1q and tumor necrosis factor related protein 1
C21ORF2 chromosome 21 open reading frame 2
C5ORF42 chromosome 5 open reading frame 42
CAMK1G calcium/calmodulin-dependent protein kinase IG
CCL13 chemokine (C-C motif) ligand 13
CD22 CD22 molecule
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CDO1 cysteine dioxygenase type 1
CFAP45 cilia and flagella associated protein 45
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLDN17 claudin 17
CLIC5 chloride intracellular channel 5
COL5A2 collagen, type V, alpha 2
COL6A1 collagen, type VI, alpha 1
COMMD4 COMM domain containing 4
CPB1 carboxypeptidase B1 (tissue)
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCBLD2 discoidin, CUB and LCCL domain containing 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EGFR epidermal growth factor receptor
FRMD1 FERM domain containing 1
FRMD8 FERM domain containing 8
FRS3 fibroblast growth factor receptor substrate 3
FSHB follicle stimulating hormone, beta polypeptide
GSPT2 G1 to S phase transition 2
HIST1H3E histone cluster 1, H3e
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IGFBP5 insulin-like growth factor binding protein 5
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
ITGA8 integrin, alpha 8
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIF5A kinesin family member 5A
KLHL25 kelch-like family member 25
LAT2 linker for activation of T cells family, member 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LINC00216 long intergenic non-protein coding RNA 216
MALL mal, T-cell differentiation protein-like
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEF2C myocyte enhancer factor 2C
MEF2D myocyte enhancer factor 2D
METTL16 methyltransferase like 16
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MMP3 matrix metallopeptidase 3
MOGAT2 monoacylglycerol O-acyltransferase 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NDRG2 NDRG family member 2
NOVA2 neuro-oncological ventral antigen 2
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PADI3 peptidyl arginine deiminase, type III
PAX8 paired box 8
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PEX3 peroxisomal biogenesis factor 3
PLXNA2 plexin A2
POLRMT polymerase (RNA) mitochondrial (DNA directed)
PPP5C protein phosphatase 5, catalytic subunit
PRTN3 proteinase 3
PTCH1 patched 1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTK2B protein tyrosine kinase 2 beta
PURA purine-rich element binding protein A
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RUNX1 runt-related transcription factor 1
S100A1 S100 calcium binding protein A1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIRT5 sirtuin 5
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SMCP sperm mitochondria-associated cysteine-rich protein
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYN2 synapsin II
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNK2 tyrosine kinase, non-receptor, 2
TRIM29 tripartite motif containing 29
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TTLL4 tubulin tyrosine ligase-like family member 4
UBR2 ubiquitin protein ligase E3 component n-recognin 2
USP22 ubiquitin specific peptidase 22
XYLB xylulokinase homolog (H. influenzae)
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
AMH anti-Mullerian hormone
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMCX2 armadillo repeat containing, X-linked 2
BHLHE41 basic helix-loop-helix family, member e41
BMP15 bone morphogenetic protein 15
CA5BP1 carbonic anhydrase VB pseudogene 1
CD34 CD34 molecule
CDK18 cyclin-dependent kinase 18
CDR2L cerebellar degeneration-related protein 2-like
CENPO centromere protein O
CGA glycoprotein hormones, alpha polypeptide
CIDEC cell death-inducing DFFA-like effector c
CUEDC1 CUE domain containing 1
CUZD1 CUB and zona pellucida-like domains 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DIXDC1 DIX domain containing 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAL4 dynein, axonemal, light chain 4
DNALI1 dynein, axonemal, light intermediate chain 1
EMID1 EMI domain containing 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM131A family with sequence similarity 131, member A
FAM198B family with sequence similarity 198, member B
FAM204A family with sequence similarity 204, member A
FOSL1 FOS-like antigen 1
GCHFR GTP cyclohydrolase I feedback regulator
GID4 GID complex subunit 4
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR143 G protein-coupled receptor 143
GUSBP3 glucuronidase, beta pseudogene 3
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HOXA4 homeobox A4
HOXC10 homeobox C10
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFT81 intraflagellar transport 81
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAMP3 lysosomal-associated membrane protein 3
LIF leukemia inhibitory factor
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MBTD1 mbt domain containing 1
MMRN2 multimerin 2
NYNRIN NYN domain and retroviral integrase containing
OCLM oculomedin
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDIA3 protein disulfide isomerase family A, member 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHF14 PHD finger protein 14
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
POLM polymerase (DNA directed), mu
POM121 POM121 transmembrane nucleoporin
PPP1R9A protein phosphatase 1, regulatory subunit 9A
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RCAN3 RCAN family member 3
RFPL1S RFPL1 antisense RNA 1
RGS20 regulator of G-protein signaling 20
RIN1 Ras and Rab interactor 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUNDC3B RUN domain containing 3B
SAYSD1 SAYSVFN motif domain containing 1
SCAI suppressor of cancer cell invasion
SCARA3 scavenger receptor class A, member 3
SECTM1 secreted and transmembrane 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SGK1 serum/glucocorticoid regulated kinase 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLPI secretory leukocyte peptidase inhibitor
SNTA1 syntrophin, alpha 1
SPEG SPEG complex locus
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SYBU syntabulin (syntaxin-interacting)
TBC1D2 TBC1 domain family, member 2
TEX40 testis expressed 40
TMEM254 transmembrane protein 254
TMPRSS4 transmembrane protease, serine 4
TRIM36 tripartite motif containing 36
TSC22D4 TSC22 domain family, member 4
UNC93B1 unc-93 homolog B1 (C. elegans)
WDR76 WD repeat domain 76
WDR78 WD repeat domain 78
ZNF230 zinc finger protein 230
ZNF37BP zinc finger protein 37B, pseudogene
ZNF552 zinc finger protein 552
ZNF573 zinc finger protein 573
ZNF816 zinc finger protein 816