iopromide-4504 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the iopromide-4504 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AHSP alpha hemoglobin stabilizing protein
AKAP11 A kinase (PRKA) anchor protein 11
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARL3 ADP-ribosylation factor-like 3
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF7IP activating transcription factor 7 interacting protein
BLZF1 basic leucine zipper nuclear factor 1
BMPR1B bone morphogenetic protein receptor, type IB
C16ORF58 chromosome 16 open reading frame 58
C9ORF116 chromosome 9 open reading frame 116
CCDC93 coiled-coil domain containing 93
CD79B CD79b molecule, immunoglobulin-associated beta
CHAT choline O-acetyltransferase
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLCN5 chloride channel, voltage-sensitive 5
CNGA1 cyclic nucleotide gated channel alpha 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL2A1 collagen, type II, alpha 1
CPZ carboxypeptidase Z
CTNS cystinosin, lysosomal cystine transporter
CUZD1 CUB and zona pellucida-like domains 1
DCTN1 dynactin 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
ECE1 endothelin converting enzyme 1
EDNRB endothelin receptor type B
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FBXO11 F-box protein 11
FBXO21 F-box protein 21
FLT1 fms-related tyrosine kinase 1
GADD45B growth arrest and DNA-damage-inducible, beta
GLB1L2 galactosidase, beta 1-like 2
H2AFX H2A histone family, member X
HDAC7 histone deacetylase 7
HOMER3 homer scaffolding protein 3
HR hair growth associated
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
ITGB4 integrin, beta 4
JAK2 Janus kinase 2
KCTD14 potassium channel tetramerization domain containing 14
KIAA0319L KIAA0319-like
KIAA1467 KIAA1467
KLF12 Kruppel-like factor 12
KLHL22 kelch-like family member 22
LRRC15 leucine rich repeat containing 15
LTB4R leukotriene B4 receptor
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MLXIP MLX interacting protein
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MT1M metallothionein 1M
NCOR2 nuclear receptor corepressor 2
NIPAL2 NIPA-like domain containing 2
NOX1 NADPH oxidase 1
NPR2 natriuretic peptide receptor 2
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NRF1 nuclear respiratory factor 1
OGFR opioid growth factor receptor
OLFM1 olfactomedin 1
PADI2 peptidyl arginine deiminase, type II
PDE4DIP phosphodiesterase 4D interacting protein
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXDC1 plexin domain containing 1
PPARD peroxisome proliferator-activated receptor delta
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PTPRU protein tyrosine phosphatase, receptor type, U
RAD51B RAD51 paralog B
RASA3 RAS p21 protein activator 3
RBMS2 RNA binding motif, single stranded interacting protein 2
RGS12 regulator of G-protein signaling 12
RND1 Rho family GTPase 1
SFXN3 sideroflexin 3
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMG6 SMG6 nonsense mediated mRNA decay factor
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SPPL2B signal peptide peptidase like 2B
ST7L suppression of tumorigenicity 7 like
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAS2R10 taste receptor, type 2, member 10
TLK1 tousled-like kinase 1
TMC6 transmembrane channel-like 6
TP73-AS1 TP73 antisense RNA 1
TPM3 tropomyosin 3
TSNAXIP1 translin-associated factor X interacting protein 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WNT16 wingless-type MMTV integration site family, member 16
WSB1 WD repeat and SOCS box containing 1
WT1 Wilms tumor 1
YPEL1 yippee-like 1 (Drosophila)
ZNF44 zinc finger protein 44

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
AGMAT agmatine ureohydrolase (agmatinase)
AK5 adenylate kinase 5
ALPK1 alpha-kinase 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMCX4 armadillo repeat containing, X-linked 4
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BMP4 bone morphogenetic protein 4
C22ORF29 chromosome 22 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
CCDC106 coiled-coil domain containing 106
CCL27 chemokine (C-C motif) ligand 27
CCNO cyclin O
CDHR2 cadherin-related family member 2
CDK6 cyclin-dependent kinase 6
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CIDEB cell death-inducing DFFA-like effector b
CLCN6 chloride channel, voltage-sensitive 6
CNTN1 contactin 1
CRYGC crystallin, gamma C
CSF1R colony stimulating factor 1 receptor
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DPF3 D4, zinc and double PHD fingers, family 3
EXOC6B exocyst complex component 6B
FAM120C family with sequence similarity 120C
FAM46C family with sequence similarity 46, member C
FBXL7 F-box and leucine-rich repeat protein 7
FLJ10038 uncharacterized protein FLJ10038
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR27 G protein-coupled receptor 27
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1D histone cluster 1, H1d
HIST1H2BM histone cluster 1, H2bm
HIST1H3A histone cluster 1, H3a
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HMOX1 heme oxygenase 1
HOXA7 homeobox A7
HOXC5 homeobox C5
HPN hepsin
IL12A interleukin 12A
IL36A interleukin 36, alpha
KIRREL kin of IRRE like (Drosophila)
KLF3 Kruppel-like factor 3 (basic)
KRT86 keratin 86, type II
LIMD2 LIM domain containing 2
LOC729164 hCG1732469
LPPR1 lipid phosphate phosphatase-related protein type 1
LTC4S leukotriene C4 synthase
LY86 lymphocyte antigen 86
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
NNAT neuronatin
NPFFR1 neuropeptide FF receptor 1
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPIPB15 nuclear pore complex interacting protein family, member B15
NT5M 5',3'-nucleotidase, mitochondrial
OVGP1 oviductal glycoprotein 1, 120kDa
PICK1 protein interacting with PRKCA 1
PID1 phosphotyrosine interaction domain containing 1
PODNL1 podocan-like 1
PPP1R17 protein phosphatase 1, regulatory subunit 17
PRR14L proline rich 14-like
RIBC2 RIB43A domain with coiled-coils 2
RNF122 ring finger protein 122
RNF43 ring finger protein 43
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAYSD1 SAYSVFN motif domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC22A14 solute carrier family 22, member 14
SLN sarcolipin
SND1-IT1 SND1 intronic transcript 1
SNPH syntaphilin
SOSTDC1 sclerostin domain containing 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNGR3 synaptogyrin 3
TAOK1 TAO kinase 1
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TESPA1 thymocyte expressed, positive selection associated 1
TMEM206 transmembrane protein 206
TMEM8B transmembrane protein 8B
VEZT vezatin, adherens junctions transmembrane protein
XDH xanthine dehydrogenase
ZFHX2 zinc finger homeobox 2
ZNF639 zinc finger protein 639
ZNF671 zinc finger protein 671
ZNF76 zinc finger protein 76
ZNF778 zinc finger protein 778