iopromide-3481 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the iopromide-3481 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
AGRN agrin
ALMS1 Alstrom syndrome protein 1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARL4C ADP-ribosylation factor-like 4C
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BPGM 2,3-bisphosphoglycerate mutase
C3ORF18 chromosome 3 open reading frame 18
CASP2 caspase 2, apoptosis-related cysteine peptidase
CFLAR CASP8 and FADD-like apoptosis regulator
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF13 DDB1 and CUL4 associated factor 13
DCAF15 DDB1 and CUL4 associated factor 15
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DPYS dihydropyrimidinase
ECE1 endothelin converting enzyme 1
EGFR epidermal growth factor receptor
ERAP1 endoplasmic reticulum aminopeptidase 1
EVPL envoplakin
FGD1 FYVE, RhoGEF and PH domain containing 1
FILIP1L filamin A interacting protein 1-like
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPATCH4 G patch domain containing 4
GPR157 G protein-coupled receptor 157
GREB1 growth regulation by estrogen in breast cancer 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HFE hemochromatosis
HIST1H4F histone cluster 1, H4f
HMGN5 high mobility group nucleosome binding domain 5
HMOX1 heme oxygenase 1
HOXA10 homeobox A10
IL17RA interleukin 17 receptor A
IL6ST interleukin 6 signal transducer
ITGA10 integrin, alpha 10
JAK2 Janus kinase 2
KLHL22 kelch-like family member 22
KRT17 keratin 17, type I
MAP4 microtubule-associated protein 4
MED18 mediator complex subunit 18
METTL7A methyltransferase like 7A
MVP major vault protein
MYL10 myosin, light chain 10, regulatory
NGLY1 N-glycanase 1
NMT2 N-myristoyltransferase 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PCM1 pericentriolar material 1
PDLIM5 PDZ and LIM domain 5
PER1 period circadian clock 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLK3 polo-like kinase 3
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PXN paxillin
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REPS1 RALBP1 associated Eps domain containing 1
RETN resistin
RFPL3 ret finger protein-like 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF2 ring finger protein 2
RNFT1 ring finger protein, transmembrane 1
SERGEF secretion regulating guanine nucleotide exchange factor
SMAD5 SMAD family member 5
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STARD3 StAR-related lipid transfer (START) domain containing 3
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAZ tafazzin
TBKBP1 TBK1 binding protein 1
TBX10 T-box 10
TBXA2R thromboxane A2 receptor
TGFB2 transforming growth factor, beta 2
TLK1 tousled-like kinase 1
TM6SF1 transmembrane 6 superfamily member 1
TMEM63A transmembrane protein 63A
TMLHE trimethyllysine hydroxylase, epsilon
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF2 TNF receptor-associated factor 2
UHRF1BP1L UHRF1 binding protein 1-like
USB1 U6 snRNA biogenesis 1
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
WDR76 WD repeat domain 76
WIZ widely interspaced zinc finger motifs
YIPF2 Yip1 domain family, member 2
ZNF428 zinc finger protein 428
ZNF440 zinc finger protein 440
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ADGRE5 adhesion G protein-coupled receptor E5
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMPD1 adenosine monophosphate deaminase 1
ANKRD36 ankyrin repeat domain 36
ANXA2P3 annexin A2 pseudogene 3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ASAP1-IT1 ASAP1 intronic transcript 1
ASB9 ankyrin repeat and SOCS box containing 9
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BFSP1 beaded filament structural protein 1, filensin
BGLAP bone gamma-carboxyglutamate (gla) protein
CAPN15 calpain 15
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC121 coiled-coil domain containing 121
CCDC85C coiled-coil domain containing 85C
CHRM3 cholinergic receptor, muscarinic 3
CLDN9 claudin 9
CRELD1 cysteine-rich with EGF-like domains 1
CRY2 cryptochrome circadian clock 2
CTC1 CTS telomere maintenance complex component 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DEAF1 DEAF1 transcription factor
DSCAM Down syndrome cell adhesion molecule
EFHD2 EF-hand domain family, member D2
EPHX2 epoxide hydrolase 2, cytoplasmic
EPPK1 epiplakin 1
FAM131A family with sequence similarity 131, member A
FGF23 fibroblast growth factor 23
FMOD fibromodulin
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR143 G protein-coupled receptor 143
GTPBP2 GTP binding protein 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H3B histone cluster 1, H3b
HS1BP3 HCLS1 binding protein 3
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
INPP5J inositol polyphosphate-5-phosphatase J
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIF13B kinesin family member 13B
KRT13 keratin 13, type I
LIME1 Lck interacting transmembrane adaptor 1
LINC00115 long intergenic non-protein coding RNA 115
LOC390998 ribosomal protein L10 pseudogene
LPAR4 lysophosphatidic acid receptor 4
LRP3 low density lipoprotein receptor-related protein 3
LRRC37A2 leucine rich repeat containing 37, member A2
MAST3 microtubule associated serine/threonine kinase 3
MATK megakaryocyte-associated tyrosine kinase
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MRPL52 mitochondrial ribosomal protein L52
NPM3 nucleophosmin/nucleoplasmin 3
NPY1R neuropeptide Y receptor Y1
NT5E 5'-nucleotidase, ecto (CD73)
NXPH4 neurexophilin 4
P3H1 prolyl 3-hydroxylase 1
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLD2 phospholipase D2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPP1R26 protein phosphatase 1, regulatory subunit 26
PRPH peripherin
PTPRE protein tyrosine phosphatase, receptor type, E
RAB4B RAB4B, member RAS oncogene family
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF121 ring finger protein 121
RPAP1 RNA polymerase II associated protein 1
RPH3AL rabphilin 3A-like (without C2 domains)
SAMHD1 SAM domain and HD domain 1
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SH2B3 SH2B adaptor protein 3
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A8 solute carrier family 12, member 8
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SND1-IT1 SND1 intronic transcript 1
STAG3 stromal antigen 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TBC1D19 TBC1 domain family, member 19
TESK1 testis-specific kinase 1
TMC5 transmembrane channel-like 5
TMEM104 transmembrane protein 104
TMPRSS3 transmembrane protease, serine 3
TOM1 target of myb1 (chicken)
TRABD TraB domain containing
TRAIP TRAF interacting protein
TUBA3C tubulin, alpha 3c
TUBGCP5 tubulin, gamma complex associated protein 5
VAX2 ventral anterior homeobox 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VGF VGF nerve growth factor inducible
ZNF250 zinc finger protein 250
ZNF35 zinc finger protein 35
ZNF586 zinc finger protein 586
ZNF747 zinc finger protein 747