iopanoic acid-6348 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the iopanoic acid-6348 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
AKAP7 A kinase (PRKA) anchor protein 7
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARID1A AT rich interactive domain 1A (SWI-like)
ARNT aryl hydrocarbon receptor nuclear translocator
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BMP1 bone morphogenetic protein 1
BMP7 bone morphogenetic protein 7
CA1 carbonic anhydrase I
CCDC132 coiled-coil domain containing 132
CCR7 chemokine (C-C motif) receptor 7
CD300A CD300a molecule
CDC14A cell division cycle 14A
CENPJ centromere protein J
CEP68 centrosomal protein 68kDa
CXCL12 chemokine (C-X-C motif) ligand 12
CYBA cytochrome b-245, alpha polypeptide
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DCAF11 DDB1 and CUL4 associated factor 11
DNAAF1 dynein, axonemal, assembly factor 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DUSP9 dual specificity phosphatase 9
DVL2 dishevelled segment polarity protein 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EDIL3 EGF-like repeats and discoidin I-like domains 3
EMP1 epithelial membrane protein 1
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ERAP1 endoplasmic reticulum aminopeptidase 1
FNDC3A fibronectin type III domain containing 3A
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GBP1 guanylate binding protein 1, interferon-inducible
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GGT1 gamma-glutamyltransferase 1
GIMAP5 GTPase, IMAP family member 5
HFE hemochromatosis
HOXC10 homeobox C10
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL17RB interleukin 17 receptor B
INO80B INO80 complex subunit B
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCTD13 potassium channel tetramerization domain containing 13
KIF5A kinesin family member 5A
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KRT9 keratin 9, type I
MINK1 misshapen-like kinase 1
MRC2 mannose receptor, C type 2
MTUS1 microtubule associated tumor suppressor 1
MZF1 myeloid zinc finger 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NELL2 NEL-like 2 (chicken)
NF1 neurofibromin 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAIP2B poly(A) binding protein interacting protein 2B
PAPPA2 pappalysin 2
PCDHGC3 protocadherin gamma subfamily C, 3
PCM1 pericentriolar material 1
PDCD2 programmed cell death 2
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLD2 phospholipase D2
PLK3 polo-like kinase 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PTCRA pre T-cell antigen receptor alpha
R3HCC1L R3H domain and coiled-coil containing 1-like
R3HDM1 R3H domain containing 1
RNF122 ring finger protein 122
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
RPS3A ribosomal protein S3A
RUNX1 runt-related transcription factor 1
SAPCD1 suppressor APC domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SIDT2 SID1 transmembrane family, member 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
STBD1 starch binding domain 1
STMN4 stathmin-like 4
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THOC5 THO complex 5
TLN2 talin 2
TRIO trio Rho guanine nucleotide exchange factor
TSC22D2 TSC22 domain family, member 2
UNC13A unc-13 homolog A (C. elegans)
USB1 U6 snRNA biogenesis 1
VCL vinculin
VN1R1 vomeronasal 1 receptor 1
WRAP53 WD repeat containing, antisense to TP53

decreased expression

Symbol Name
ANKZF1 ankyrin repeat and zinc finger domain containing 1
BPGM 2,3-bisphosphoglycerate mutase
C11ORF63 chromosome 11 open reading frame 63
CAPG capping protein (actin filament), gelsolin-like
CCNJ cyclin J
CHN1 chimerin 1
CLDN4 claudin 4
CLSPN claspin
COPG1 coatomer protein complex, subunit gamma 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTNNBL1 catenin, beta like 1
CUL9 cullin 9
CXORF56 chromosome X open reading frame 56
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
ECM1 extracellular matrix protein 1
EGF epidermal growth factor
EMD emerin
EPHA4 EPH receptor A4
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
F3 coagulation factor III (thromboplastin, tissue factor)
FXN frataxin
FXR2 fragile X mental retardation, autosomal homolog 2
GAREM GRB2 associated, regulator of MAPK1
GPR137B G protein-coupled receptor 137B
H2AFY2 H2A histone family, member Y2
HHLA3 HERV-H LTR-associating 3
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HLX H2.0-like homeobox
IL13RA2 interleukin 13 receptor, alpha 2
ISG20 interferon stimulated exonuclease gene 20kDa
JMJD4 jumonji domain containing 4
JUNB jun B proto-oncogene
JUP junction plakoglobin
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KDM4D lysine (K)-specific demethylase 4D
KIFAP3 kinesin-associated protein 3
KRT75 keratin 75, type II
L2HGDH L-2-hydroxyglutarate dehydrogenase
LMBR1L limb development membrane protein 1-like
LNPEP leucyl/cystinyl aminopeptidase
LUC7L LUC7-like (S. cerevisiae)
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MCOLN1 mucolipin 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MOGS mannosyl-oligosaccharide glucosidase
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MUM1 melanoma associated antigen (mutated) 1
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NRTN neurturin
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PALMD palmdelphin
PECR peroxisomal trans-2-enoyl-CoA reductase
PEX26 peroxisomal biogenesis factor 26
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POMT2 protein-O-mannosyltransferase 2
PTDSS2 phosphatidylserine synthase 2
QTRT1 queuine tRNA-ribosyltransferase 1
RIBC2 RIB43A domain with coiled-coils 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF141 ring finger protein 141
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SH3BGR SH3 domain binding glutamate-rich protein
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC22A18 solute carrier family 22, member 18
SLC46A3 solute carrier family 46, member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
SYNPO synaptopodin
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBX19 T-box 19
TDRD7 tudor domain containing 7
TLN1 talin 1
TMEM121 transmembrane protein 121
TMEM209 transmembrane protein 209
TMEM62 transmembrane protein 62
TMEM8A transmembrane protein 8A
TNNI3 troponin I type 3 (cardiac)
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRAPPC11 trafficking protein particle complex 11
TRAPPC13 trafficking protein particle complex 13
TROAP trophinin associated protein
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
WDR91 WD repeat domain 91
ZBTB44 zinc finger and BTB domain containing 44
ZC3H12A zinc finger CCCH-type containing 12A
ZNF175 zinc finger protein 175
ZNF324 zinc finger protein 324
ZNF415 zinc finger protein 415
ZNF767P zinc finger family member 767, pseudogene