iopanoic acid-3527 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the iopanoic acid-3527 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
AIF1 allograft inflammatory factor 1
AMACR alpha-methylacyl-CoA racemase
ANKMY1 ankyrin repeat and MYND domain containing 1
APLP1 amyloid beta (A4) precursor-like protein 1
APOE apolipoprotein E
ASAP1-IT1 ASAP1 intronic transcript 1
ATF6B activating transcription factor 6 beta
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
AUTS2 autism susceptibility candidate 2
BMP6 bone morphogenetic protein 6
C3 complement component 3
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAPN9 calpain 9
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC25C cell division cycle 25C
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIB2 calcium and integrin binding family member 2
CRLF2 cytokine receptor-like factor 2
CTRL chymotrypsin-like
CUL7 cullin 7
DGCR8 DGCR8 microprocessor complex subunit
DGKE diacylglycerol kinase, epsilon 64kDa
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DUSP9 dual specificity phosphatase 9
ECE1 endothelin converting enzyme 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FGFR1 fibroblast growth factor receptor 1
FKBP15 FK506 binding protein 15, 133kDa
FOXG1 forkhead box G1
GLIPR1 GLI pathogenesis-related 1
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPATCH4 G patch domain containing 4
GPR137 G protein-coupled receptor 137
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HLA-C major histocompatibility complex, class I, C
HMGN5 high mobility group nucleosome binding domain 5
HOXA4 homeobox A4
HPS1 Hermansky-Pudlak syndrome 1
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
ICAM1 intercellular adhesion molecule 1
KAZN kazrin, periplakin interacting protein
LARP7 La ribonucleoprotein domain family, member 7
LCMT2 leucine carboxyl methyltransferase 2
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MALT1 MALT1 paracaspase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL16 methyltransferase like 16
MLANA melan-A
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MSMB microseminoprotein, beta-
MUC1 mucin 1, cell surface associated
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NUP188 nucleoporin 188kDa
NUP88 nucleoporin 88kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PAWR PRKC, apoptosis, WT1, regulator
PCDHB6 protocadherin beta 6
PGAP3 post-GPI attachment to proteins 3
PHF14 PHD finger protein 14
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLAGL1 pleiomorphic adenoma gene-like 1
PLAUR plasminogen activator, urokinase receptor
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PXDC1 PX domain containing 1
RTEL1 regulator of telomere elongation helicase 1
SCAPER S-phase cyclin A-associated protein in the ER
SCUBE3 signal peptide, CUB domain, EGF-like 3
SKAP1 src kinase associated phosphoprotein 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SNX13 sorting nexin 13
SOS2 son of sevenless homolog 2 (Drosophila)
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STK17B serine/threonine kinase 17b
SUMO1 small ubiquitin-like modifier 1
SYCP2 synaptonemal complex protein 2
SYT5 synaptotagmin V
TCP11L1 t-complex 11, testis-specific-like 1
TIGD6 tigger transposable element derived 6
TM4SF4 transmembrane 4 L six family member 4
UROD uroporphyrinogen decarboxylase
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
WDR1 WD repeat domain 1
WDR55 WD repeat domain 55
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF287 zinc finger protein 287
ZNF329 zinc finger protein 329
ZNF419 zinc finger protein 419
ZNF500 zinc finger protein 500
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ADAP2 ArfGAP with dual PH domains 2
ADGRG2 adhesion G protein-coupled receptor G2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARRB1 arrestin, beta 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B9D2 B9 protein domain 2
BAHCC1 BAH domain and coiled-coil containing 1
BMP4 bone morphogenetic protein 4
C10ORF95 chromosome 10 open reading frame 95
C5 complement component 5
C7ORF43 chromosome 7 open reading frame 43
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC186 coiled-coil domain containing 186
CCDC85C coiled-coil domain containing 85C
CCNO cyclin O
CENPO centromere protein O
CEP170B centrosomal protein 170B
CGA glycoprotein hormones, alpha polypeptide
CHPF chondroitin polymerizing factor
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCF1 cardiotrophin-like cytokine factor 1
CORT cortistatin
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPTP ceramide-1-phosphate transfer protein
CRELD1 cysteine-rich with EGF-like domains 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DVL1 dishevelled segment polarity protein 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EN2 engrailed homeobox 2
FAM160B2 family with sequence similarity 160, member B2
FBRS fibrosin
FLNC filamin C, gamma
FRMD1 FERM domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
GALK1 galactokinase 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRTP1 growth hormone regulated TBC protein 1
HOXC8 homeobox C8
INO80D INO80 complex subunit D
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA0319L KIAA0319-like
KLF2 Kruppel-like factor 2
KLF3 Kruppel-like factor 3 (basic)
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT24 keratin 24, type I
LINS lines homolog (Drosophila)
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MAGEA6 melanoma antigen family A6
MCOLN1 mucolipin 1
MED15 mediator complex subunit 15
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVD mevalonate (diphospho) decarboxylase
NAV2 neuron navigator 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
PC pyruvate carboxylase
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLXNA3 plexin A3
POM121 POM121 transmembrane nucleoporin
PRODH proline dehydrogenase (oxidase) 1
PSKH1 protein serine kinase H1
RANGRF RAN guanine nucleotide release factor
RASAL1 RAS protein activator like 1 (GAP1 like)
RPGRIP1L RPGRIP1-like
RPL10L ribosomal protein L10-like
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
STRN4 striatin, calmodulin binding protein 4
SUGP1 SURP and G patch domain containing 1
TBX19 T-box 19
TCP10 t-complex 10
TGFB3 transforming growth factor, beta 3
THRAP3 thyroid hormone receptor associated protein 3
TMEM104 transmembrane protein 104
TMEM120B transmembrane protein 120B
TOM1 target of myb1 (chicken)
TRAIP TRAF interacting protein
TSGA10 testis specific, 10
TUBA3D tubulin, alpha 3d
TYK2 tyrosine kinase 2
UNC119 unc-119 homolog (C. elegans)
UPP1 uridine phosphorylase 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
XK X-linked Kx blood group
XYLT2 xylosyltransferase II
ZNF282 zinc finger protein 282
ZNF350 zinc finger protein 350
ZNF639 zinc finger protein 639