iopanoic acid-2965 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the iopanoic acid-2965 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACOT11 acyl-CoA thioesterase 11
ANGPTL4 angiopoietin-like 4
APOM apolipoprotein M
ARID5A AT rich interactive domain 5A (MRF1-like)
ARMCX4 armadillo repeat containing, X-linked 4
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BAIAP3 BAI1-associated protein 3
BMP15 bone morphogenetic protein 15
BMP7 bone morphogenetic protein 7
C17ORF53 chromosome 17 open reading frame 53
C3ORF18 chromosome 3 open reading frame 18
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCDC9 coiled-coil domain containing 9
CCL22 chemokine (C-C motif) ligand 22
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNOT4 CCR4-NOT transcription complex, subunit 4
COL7A1 collagen, type VII, alpha 1
CRTC1 CREB regulated transcription coactivator 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DBT dihydrolipoamide branched chain transacylase E2
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOCK6 dedicator of cytokinesis 6
DOHH deoxyhypusine hydroxylase/monooxygenase
EGR2 early growth response 2
EXD3 exonuclease 3'-5' domain containing 3
FADS3 fatty acid desaturase 3
FER1L4 fer-1-like family member 4, pseudogene (functional)
FLRT1 fibronectin leucine rich transmembrane protein 1
GAS7 growth arrest-specific 7
GLRX3 glutaredoxin 3
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRM6 glutamate receptor, metabotropic 6
GSTM5 glutathione S-transferase mu 5
HLA-DMB major histocompatibility complex, class II, DM beta
HOMER3 homer scaffolding protein 3
IGLV1-44 immunoglobulin lambda variable 1-44
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LMNA lamin A/C
MAN1B1 mannosidase, alpha, class 1B, member 1
MAP4 microtubule-associated protein 4
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MIR22HG MIR22 host gene
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTUS1 microtubule associated tumor suppressor 1
MXD4 MAX dimerization protein 4
NEURL1 neuralized E3 ubiquitin protein ligase 1
NMT2 N-myristoyltransferase 2
NRCAM neuronal cell adhesion molecule
OBSL1 obscurin-like 1
PAPPA2 pappalysin 2
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHGA8 protocadherin gamma subfamily A, 8
PDLIM2 PDZ and LIM domain 2 (mystique)
PLD3 phospholipase D family, member 3
POU6F1 POU class 6 homeobox 1
PRAMEF11 PRAME family member 11
PRB1 proline-rich protein BstNI subfamily 1
RCN3 reticulocalbin 3, EF-hand calcium binding domain
REC8 REC8 meiotic recombination protein
RHOD ras homolog family member D
RNF39 ring finger protein 39
RPL13P5 ribosomal protein L13 pseudogene 5
RPS3A ribosomal protein S3A
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC25A44 solute carrier family 25, member 44
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SOX12 SRY (sex determining region Y)-box 12
SPTAN1 spectrin, alpha, non-erythrocytic 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAPBP TAP binding protein (tapasin)
TBXA2R thromboxane A2 receptor
TCP11L1 t-complex 11, testis-specific-like 1
TEK TEK tyrosine kinase, endothelial
TICAM1 toll-like receptor adaptor molecule 1
TLE3 transducin-like enhancer of split 3
TNS1 tensin 1
TRIP11 thyroid hormone receptor interactor 11
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSNAXIP1 translin-associated factor X interacting protein 1
TTC22 tetratricopeptide repeat domain 22
VASP vasodilator-stimulated phosphoprotein
VIPR2 vasoactive intestinal peptide receptor 2
WDTC1 WD and tetratricopeptide repeats 1
ZBTB22 zinc finger and BTB domain containing 22
ZFP36L2 ZFP36 ring finger protein-like 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF234 zinc finger protein 234
ZNF337 zinc finger protein 337
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AKTIP AKT interacting protein
ALG3 ALG3, alpha-1,3- mannosyltransferase
AMPD2 adenosine monophosphate deaminase 2
ANKRD36 ankyrin repeat domain 36
ARID4A AT rich interactive domain 4A (RBP1-like)
ARMC7 armadillo repeat containing 7
BYSL bystin-like
C12ORF43 chromosome 12 open reading frame 43
CAAP1 caspase activity and apoptosis inhibitor 1
CBR1 carbonyl reductase 1
CCNT1 cyclin T1
CDK6 cyclin-dependent kinase 6
COA7 cytochrome c oxidase assembly factor 7 (putative)
COQ4 coenzyme Q4
CRYZ crystallin, zeta (quinone reductase)
CTPS2 CTP synthase 2
CTSG cathepsin G
CUEDC2 CUE domain containing 2
DBR1 debranching RNA lariats 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEPDC1 DEP domain containing 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNAL4 dynein, axonemal, light chain 4
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EBNA1BP2 EBNA1 binding protein 2
ECI1 enoyl-CoA delta isomerase 1
EXOC2 exocyst complex component 2
FAM118A family with sequence similarity 118, member A
FAM188A family with sequence similarity 188, member A
FAR2 fatty acyl CoA reductase 2
FZD2 frizzled class receptor 2
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GRAMD1B GRAM domain containing 1B
GRB2 growth factor receptor-bound protein 2
GRWD1 glutamate-rich WD repeat containing 1
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HMGB3 high mobility group box 3
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IMPACT impact RWD domain protein
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCTD20 potassium channel tetramerization domain containing 20
LINC00115 long intergenic non-protein coding RNA 115
LY75 lymphocyte antigen 75
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MOCS3 molybdenum cofactor synthesis 3
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative)
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
NHEJ1 nonhomologous end-joining factor 1
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NOL6 nucleolar protein 6 (RNA-associated)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OR7E37P olfactory receptor, family 7, subfamily E, member 37 pseudogene
PGGT1B protein geranylgeranyltransferase type I, beta subunit
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
PRMT1 protein arginine methyltransferase 1
PSAT1 phosphoserine aminotransferase 1
QTRT1 queuine tRNA-ribosyltransferase 1
RCL1 RNA terminal phosphate cyclase-like 1
RPIA ribose 5-phosphate isomerase A
RPL23AP7 ribosomal protein L23a pseudogene 7
RWDD2B RWD domain containing 2B
SAMHD1 SAM domain and HD domain 1
SCRIB scribbled planar cell polarity protein
SETD6 SET domain containing 6
SFT2D2 SFT2 domain containing 2
SGMS1 sphingomyelin synthase 1
SPIDR scaffolding protein involved in DNA repair
SRSF8 serine/arginine-rich splicing factor 8
STX17 syntaxin 17
TASP1 taspase, threonine aspartase, 1
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM230 transmembrane protein 230
TMEM38B transmembrane protein 38B
TMEM80 transmembrane protein 80
TTC13 tetratricopeptide repeat domain 13
TTC27 tetratricopeptide repeat domain 27
TTF2 transcription termination factor, RNA polymerase II
TWISTNB TWIST neighbor
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
URGCP upregulator of cell proliferation
USP36 ubiquitin specific peptidase 36
USPL1 ubiquitin specific peptidase like 1
WDR3 WD repeat domain 3
YIPF1 Yip1 domain family, member 1
YY2 YY2 transcription factor
ZFP30 ZFP30 zinc finger protein
ZMPSTE24 zinc metallopeptidase STE24
ZMYM1 zinc finger, MYM-type 1
ZNF304 zinc finger protein 304
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF551 zinc finger protein 551